GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Foram encontrados 263 produtos para "GluR".
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CFMTI
CAS:CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.Fórmula:C19H16FN5OPureza:97.88%Cor e Forma:White SolidPeso molecular:349.36Ref: TM-T3482
1mg57,00€2mg82,00€5mg120,00€1mL*10mM (DMSO)133,00€10mg170,00€25mg304,00€50mg432,00€100mg602,00€DNQX
CAS:DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)Fórmula:C8H4N4O6Pureza:97.27% - 99.1%Cor e Forma:White SolidPeso molecular:252.14VU0155041
CAS:VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).Fórmula:C14H15Cl2NO3Pureza:99.52% - 99.56%Cor e Forma:SolidPeso molecular:316.18Ref: TM-T3565
2mg38,00€5mg55,00€1mL*10mM (DMSO)60,00€10mg80,00€25mg138,00€50mg178,00€100mg285,00€200mg413,00€Ro0711401
CAS:Ro0711401 is an agonist of mGlu1 receptor.Fórmula:C18H11F3N2O3Pureza:97.57%Cor e Forma:SolidPeso molecular:360.29ADX-47273
CAS:ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).Fórmula:C20H17F2N3O2Pureza:97% - 99.22%Cor e Forma:White SolidPeso molecular:369.36FTIDC
CAS:FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.Fórmula:C18H23FN6OPureza:95.39%Cor e Forma:SolidPeso molecular:358.41Ref: TM-T3483
1mg100,00€2mg145,00€5mg215,00€1mL*10mM (DMSO)236,00€10mg340,00€25mg565,00€50mg797,00€100mg1.071,00€CX717
CAS:CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.Fórmula:C11H11N3O3Pureza:99.81%Cor e Forma:White SolidPeso molecular:233.23(S)-4CPG
CAS:(S)-4CPG ((S)-4-Carboxyphenylglycine) is a competitive mGlu1 receptor antagonist that attenuates nociceptive hypersensitivity and nociceptive abnormalities associated with sciatic nerve constriction injuries in rats, and may be used in the study of neurological disorders.Fórmula:C9H9NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:195.17Raseglurant
CAS:Raseglurant (ADX-10059) is a negative allosteric modulator of the mGlu5 receptor that demonstrates efficacy against migraine and significantly reduces haloperidol-induced catalepsy in mice, Raseglurant is widely used in neuropharmacology research to study glutamatergic modulation, motor side effects of antipsychotics, and migraine-related signaling pathways.Fórmula:C15H13FN2Pureza:99.80%Cor e Forma:White SolidPeso molecular:240.28VU0477886
CAS:VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.Fórmula:C20H13ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:392.80IEM 1754 2HBr
CAS:IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.Fórmula:C16H30N2·2HBrPureza:99.04% - 99.72%Cor e Forma:SolidPeso molecular:412.25MAP4
CAS:metabotropic glutamate receptor modulatorFórmula:C5H12NO5PPureza:98%Cor e Forma:SolidPeso molecular:197.13mGlu4 receptor agonist 1
CAS:Compound 62, an mGlu4 agonist, has a 308 nM EC50 with anxiolytic and antipsychotic effects.Fórmula:C21H15ClN4O2Cor e Forma:SolidPeso molecular:390.82ADX71743
CAS:ADX71743 is a selective, non-competitive mGlu7 negative allosteric modulator (NAM) that crosses the blood-brain barrier and exhibits anti-anxiety activity.Fórmula:C17H19NO2Pureza:99.27%Cor e Forma:SolidPeso molecular:269.34VU 0360223
CAS:VU 0360223 is a negative allosteric modulator of mGlu5.Fórmula:C15H9FN2SPureza:98%Cor e Forma:SolidPeso molecular:268.31NS 1209
CAS:NS 1209 (SPD 502) is a AMPA receptor antagonist.Fórmula:C24H27N4NaO7SPureza:98%Cor e Forma:SolidPeso molecular:538.55RO5488608
CAS:RO5488608 is a new type of high-efficiency mGlu2/3 NAM.Fórmula:C23H17F3N2O4SCor e Forma:SolidPeso molecular:474.45A 841720
CAS:Potent, selective mGlu1 antagonist A-841720; IC50: 10 nM; 34x selectivity vs mGlu5; analgesic potential.Fórmula:C17H21N5OSCor e Forma:SolidPeso molecular:343.45L-AP4 monohydrate
CAS:L-AP4 (L-APB) is a group III mGluR agonist with EC50s: 0.13μM (mGlu4), 0.29μM (mGlu8), 1.0μM (mGlu6), 249μM (mGlu7).Fórmula:C4H12NO6PCor e Forma:SolidPeso molecular:201.115NPEC-caged-LY379268
CAS:NPEC-caged-LY379268 is a type II mGluR agonist [1].Fórmula:C16H16N2O9Cor e Forma:SolidPeso molecular:380.31
