AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 575 produtos de "AChR"
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Glycerophosphoinositol choline
CAS:<p>Glycerophosphoinositol choline is the salt of choline and glycerophosphoinositol.</p>Fórmula:C14H32NO12PCor e Forma:SolidPeso molecular:437.38Cevimeline
CAS:<p>Cevimeline: muscarinic agonist, treats dry mouth & Sjögren's, boosts saliva post-cancer radiotherapy.</p>Fórmula:C10H17NOSCor e Forma:Off-White SolidPeso molecular:199.31(±)-Darifenacin
CAS:(±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective antagonist of M3 muscarinic receptor.Fórmula:C28H30N2O2Cor e Forma:SolidPeso molecular:426.55Pirmenol hydrochloride
CAS:<p>Pirmenol hydrochloride functions by inhibiting I_K.ACh through the blockade of muscarinic receptors, demonstrating a potent effect with an IC_50 value of 0.1 μM</p>Fórmula:C22H31ClN2OCor e Forma:SolidPeso molecular:374.95VU0467485
CAS:VU0467485 boosts ACh at M4 receptors (EC50: 26.6 nM rat, 78.8 nM human), selective for M4 over M1/2/3/5.Fórmula:C17H17FN4O2SPureza:98%Cor e Forma:SolidPeso molecular:360.41Clorprenaline
CAS:<p>Clorprenaline is a β-adrenergic receptor agonist that activates adenylate cyclase, relaxation of bronchial smooth muscle cells. anti-inflammatory.</p>Fórmula:C11H16ClNOPureza:98.9%Cor e Forma:SolidPeso molecular:213.7Tebanicline dihydrochloride
CAS:<p>Tebanicline dihydrochloride: oral analgesic, nAChR modulator, Ki=37 pM at α4β2 receptors, inhibits cytisine binding.</p>Fórmula:C9H13Cl3N2OCor e Forma:SolidPeso molecular:271.57(S)-(+)-Dimethindene maleate
CAS:<p>(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1 receptors</p>Fórmula:C24H28N2O4Pureza:99.94%Cor e Forma:SolidPeso molecular:408.49Sabcomeline hydrochloride
CAS:<p>Sabcomeline is a selective M1 receptor partial agonist.</p>Fórmula:C10H16ClN3OCor e Forma:SolidPeso molecular:229.71DL-Cystine
CAS:<p>DL-Cystine is a cysteine derivative that inhibits endothelial cell proliferation by regulating TGFβ1. a GPR inhibitor and nAChR agonist .</p>Fórmula:C6H12N2O4S2Cor e Forma:SolidPeso molecular:240.3NS3861 fumarate
CAS:<p>NS3861 fumarate, a partial α3β4 nAChR agonist, binds α3β2, α4β4, α4β2 with Ki values of 0.62, 25, 7.8, 55 nM.</p>Fórmula:C16H18BrNO4SCor e Forma:SolidPeso molecular:400.29N6-Methyladenosine 5'-monophosphate disodium salt
CAS:N6-Methyladenosine 5'-monophosphate disodium salt is a glycogen phosphorylase b activator and an inhibitor of adenylate kinase II.Fórmula:C11H14N5Na2O7PPureza:99.36% - 99.36%Cor e Forma:SolidPeso molecular:405.21Fesoterodine L-mandelate
CAS:<p>Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB).</p>Fórmula:C34H45NO6Cor e Forma:SolidPeso molecular:563.735Tebanicline hydrochloride
CAS:<p>Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.</p>Fórmula:C9H12Cl2N2OPureza:91.74% - 98.71%Cor e Forma:SolidPeso molecular:235.11VU0119498
CAS:<p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>Fórmula:C15H10BrNO2Pureza:97.56%Cor e Forma:SolidPeso molecular:316.15VU0152100
CAS:<p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>Fórmula:C18H19N3O2SPureza:99.56%Cor e Forma:SolidPeso molecular:341.43Nitrobenzylthioinosine
CAS:<p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>Fórmula:C17H17N5O6SPureza:99.69% - 99.74%Cor e Forma:Off-White SolidPeso molecular:419.41NS9283
CAS:<p>NS9283, a positive allosteric modulator selective for the α4β2 form, reduces ethanol consumption.</p>Fórmula:C14H8N4OPureza:99.12%Cor e Forma:SolidPeso molecular:248.24Ethyl (triphenylphosphoranylidene) acetate
CAS:<p>Ethyl (triphenylphosphoranylidene) acetate ((Carbethoxymethylene)triphenylphosphorane) may act as an cholinesterase inhibitor that inhibits AChE and BChE.</p>Fórmula:C22H21O2PPureza:97.985%Cor e Forma:White Or Slight Yellow PowderPeso molecular:348.37ML380
CAS:<p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>Fórmula:C23H25F3N4O3SPureza:99.69%Cor e Forma:SolidPeso molecular:494.53
