AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 619 produtos de "AChR"
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Pyrantel
CAS:Pyrantel: Nicotinic agonist; causes spastic paralysis in nematodes by depolarizing block.Fórmula:C11H14N2SPureza:98%Cor e Forma:Crystals From Methanol Yellowish Crystalline PowderPeso molecular:206.31Flavoxate
CAS:<p>Flavoxate is an anticholinergic with antimuscarinic effects.</p>Fórmula:C24H25NO4Cor e Forma:SolidPeso molecular:391.46Atropine hydrobromide
CAS:Atropine hydrobromide is a biochemical.Fórmula:C17H24BrNO3Cor e Forma:SolidPeso molecular:370.28Anatabine dicitrate
Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier.Fórmula:C22H28N2O14Pureza:98%Cor e Forma:SolidPeso molecular:544.46(±)-Atropine-d3 (N-methyl-d3)
CAS:(±)-Atropine-d3 (N-methyl-d3) is a deuterated compound of (±)-Atropine. (±)-Atropine has a CAS number of 51-55-8. Atropine Sulfate is the sulfate salt of atropine, a naturally-occurring alkaloid isolated from the plant Atropa belladonna. Atropine functions as a sympathetic, competitive antagonist of muscarinic cholinergic receptors, thereby abolishing the effects of parasympathetic stimulation.Fórmula:C17H20D3NO3Peso molecular:292.39AN317
CAS:AN317 is a selective agonist for the nicotinic acetylcholine receptor (nAChR) containing α6β2, with dissociation constants (Ki) of 6.2 nM and 4.1 nM for the α6/α3β2β3 and α4β2 receptor subtypes, respectively. It induces dopamine release in rat striatal synaptosomes, enhances the activity of dopaminergic neurons in the substantia nigra, and exhibits protective effects against the dopaminergic neurotoxin MPP+ in rat neurons. AN317 also demonstrates favorable pharmacokinetic properties in rats and permeability across the blood-brain barrier (BB).Fórmula:C13H19N3Cor e Forma:SolidPeso molecular:217.31Phenglutarimide hydrochloride
CAS:Phenglutarimide hydrochloride is an anticholinergic. It is used as an antiparkinsonian agent.Fórmula:C17H25ClN2O2Cor e Forma:SolidPeso molecular:324.85Diphenidol
CAS:<p>Diphenidol, a muscarinic antagonist, is employed as an antivertigo and antiemetic agent.</p>Fórmula:C21H27NOCor e Forma:Needles From Petroleum Ether SolidPeso molecular:309.45Oxantel
CAS:<p>Oxantel is a fumarate reductase inhibitor with anthelmintic activity.</p>Fórmula:C13H16N2OPureza:98%Cor e Forma:SolidPeso molecular:216.28Catestatin
CAS:Non-competitive inhibitor of nicotinic receptors; blocks cationic signalling and catecholamine release; stimulates histamine release. IC50 ~200-250nM.Fórmula:C107H173N37O26SPureza:98%Cor e Forma:SolidPeso molecular:2425.84Azacyclonol hydrochloride
CAS:Azacyclonol hydrochloride can be used in the treatment of chronic schizophrenia.Fórmula:C18H22ClNOCor e Forma:Off White Crystalline PowderPeso molecular:303.83Aprofene
CAS:Aprofene blocks acetylcholine receptors, used for peptic ulcers, endarteritis, cholecystitis, and colitis.Fórmula:C21H27NO2Cor e Forma:SolidPeso molecular:325.44VU0029767
CAS:<p>VU0029767 is an allosteric enhancer of the M1 muscarinic receptor, capable of modulating the receptor's activity. This compound enhances M1 receptor activity by increasing agonist affinity. However, VU0029767 demonstrates distinct characteristics from other compounds, particularly under varying experimental conditions such as its interaction with mutated M1 receptors and its effects on downstream signaling pathways.</p>Fórmula:C21H21N3O3Cor e Forma:SolidPeso molecular:363.41Dianicline dihydrochloride
CAS:Dianicline dihydrochloride is a partial agonist of α4β2 nicotinic acetylcholine receptor. It increases cessation rates in a dose-dependent manner.Fórmula:C13H16N2OPureza:98%Cor e Forma:SolidPeso molecular:216.28Biperiden lactate
CAS:<p>Biperiden lactate is a biochemical.</p>Fórmula:C24H35NO4Cor e Forma:SolidPeso molecular:401.54N-Biotinyl p-aminophenyl arsenic acid
CAS:N-Biotinyl p-aminophenyl arsenic acid is a bifunctional reagent that binds to streptavidin and disulfide compounds. It diminishes the binding sites of rbungarotoxin on reduced nicotinic receptors with an IC50 ranging from 10-300 nM, thus shielding the receptors from irreversible alkylation by bromoacetylcholine.Fórmula:C16H22AsN3O4SCor e Forma:SolidPeso molecular:427.35Sulindac sulfide
CAS:Sulindac sulfide: NSAID targeting COX-1, inhibits Ras-Raf-1 and gamma-secretase (IC50: 20.2 μM), active sulinic acid metabolite.Fórmula:C20H17FO2SPureza:99.35%Cor e Forma:SolidPeso molecular:340.41Asoxime dichloride
CAS:Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.Fórmula:C14H16Cl2N4O3Pureza:99.75% - 99.86%Cor e Forma:SolidPeso molecular:359.21Revatropate
CAS:Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug.Fórmula:C19H27NO4SCor e Forma:SolidPeso molecular:365.49Camylofine
CAS:Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.Fórmula:C19H32N2O2·2HClPureza:98%Cor e Forma:SolidPeso molecular:393.4
