AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 619 produtos de "AChR"
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Cynandione A
CAS:Cynandione A is an acetophenone derived from Cynanchum wilfordii with anti-inflammatory activity.Fórmula:C16H14O6Pureza:99.62%Cor e Forma:SolidPeso molecular:302.28Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Fórmula:C17H22BrNOS2Pureza:98%Cor e Forma:SolidPeso molecular:400.4UFP-512
CAS:UFP-512 is a selective delta-opioid (DOP) receptor agonist.Fórmula:C31H33N5O5Pureza:98%Cor e Forma:SolidPeso molecular:555.62BMS-933043
CAS:BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Fórmula:C16H19N7OPureza:98%Cor e Forma:SolidPeso molecular:325.37ABT-418 hydrochloride
CAS:ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.Fórmula:C9H15ClN2OCor e Forma:SolidPeso molecular:202.68Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Fórmula:C31H33NO7Pureza:99.88%Cor e Forma:SolidPeso molecular:531.6AR420626
CAS:AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.Fórmula:C21H18Cl2N2O3Pureza:98.62%Cor e Forma:SolidPeso molecular:417.29VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Cor e Forma:SolidPeso molecular:432.52Tiotropium Bromide hydrate
CAS:Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Cor e Forma:SolidPeso molecular:490.43Homatropine hydrochloride
CAS:Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussiveFórmula:C16H22ClNO3Cor e Forma:SolidPeso molecular:311.8mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Fórmula:C19H22N2O2Cor e Forma:SolidPeso molecular:310.39Tematropium
CAS:Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.Fórmula:C21H31NO8SPureza:99.89%Cor e Forma:SolidPeso molecular:457.54nAChR antagonist 1
CAS:Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.Fórmula:C19H22N4O2Cor e Forma:SolidPeso molecular:338.4UB 165
CAS:Subtype-selective nicotinic agonistFórmula:C13H15ClN2Pureza:98%Cor e Forma:SolidPeso molecular:234.72(+)-Cevimeline hydrochloride hemihydrate
(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.Fórmula:C10H19ClNO1·5SPureza:98%Cor e Forma:SolidPeso molecular:244.781,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Fórmula:C22H34O5Pureza:98%Cor e Forma:SolidPeso molecular:378.5LY593093
CAS:LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.Fórmula:C32H30FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:507.6VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Fórmula:C25H27N5O2Cor e Forma:SolidPeso molecular:429.51TDI-11861
CAS:TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.Fórmula:C22H25ClF2N6O3Cor e Forma:SolidPeso molecular:494.92TAAR1 agonist 2
CAS:TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.Fórmula:C9H11NOCor e Forma:SolidPeso molecular:149.19
