AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 575 produtos de "AChR"
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Milameline
CAS:<p>Milameline is a muscarinic receptor agonist that improves cognition.</p>Fórmula:C8H14N2OCor e Forma:SolidPeso molecular:154.21Biricodar dicitrate
CAS:<p>Biricodar dicitrate (VX-710) is a potent MDR inhibitor with no anticancer activity and can be used to study prostate cancer.</p>Fórmula:C46H57N3O21Pureza:97.78% - 99.78%Cor e Forma:SolidPeso molecular:987.95Sofiniclin
CAS:<p>Sofiniclin (ABT 894) is an agonist of nicotinic acetylcholine receptor (nAChR). It is used for the research for attention-deficit/hyperactivity disorder (ADHD).</p>Fórmula:C10H11Cl2N3Pureza:98%Cor e Forma:SolidPeso molecular:244.12Bibn 99
CAS:<p>Bibn 99, a lipophilic and selective muscarinic M2 receptor antagonist, has applications in cognitive performance and Alzheimer's Disease.</p>Fórmula:C31H42ClN5O3Cor e Forma:SolidPeso molecular:568.15VU 6008667
CAS:VU 6008667 is a selective negative allosteric M5 NAM modulator (IC50s: 1.2 μM and 1.6 μM for human M5 and rat M5, respectively).Fórmula:C24H17ClF2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:438.85Rivanicline
CAS:<p>Rivanicline is a selective α4β2 nicotinic receptor agonist (Ki=26 nM), with >1,000x less affinity for α7 receptors.</p>Fórmula:C10H14N2Pureza:98%Cor e Forma:SolidPeso molecular:162.23Rapacuronium bromide
CAS:Rapacuronium bromide is an allosteric muscarinic acetylcholine receptor (mAChR) modulator.Fórmula:C37H61BrN2O4Pureza:98%Cor e Forma:SolidPeso molecular:677.8ML375
CAS:<p>ML375 is a potent, selective and CNS penetrant M5 negative allosteric modulator (NAM).</p>Fórmula:C23H15ClF2N2O2Cor e Forma:SolidPeso molecular:424.83CP-601927
CAS:<p>CP-601927 is a nicotinic acetylcholine receptor (NACHR) agonist with permeability, high affinity, and selectivity.</p>Fórmula:C12H12F3NCor e Forma:SolidPeso molecular:227.23Arecaidine propargyl ester tosylate
CAS:<p>Arecaidine propargyl ester tosylate is a muscarinic receptor agonist.</p>Fórmula:C17H21NO5SPureza:98%Cor e Forma:SolidPeso molecular:351.42VMY-2-95
CAS:<p>VMY-2-95 is an α4β2 nicotinic acetylcholine receptors (nAChRs) selective desensitizer.</p>Fórmula:C17H16N2OCor e Forma:SolidPeso molecular:264.32RJR 2429 dihydrochloride
CAS:<p>nAChR agonist that displays selectivity for α4β2</p>Fórmula:C12H18Cl2N2Pureza:98%Cor e Forma:SolidPeso molecular:261.19J 104129 fumarate
CAS:<p>M3 muscarinic receptor antagonist</p>Fórmula:C24H36N2O2Pureza:98%Cor e Forma:SolidPeso molecular:384.55Alvameline maleate
CAS:<p>Alvameline maleate is used as a Partial M1 Agonist and M2/M3 Antagonist.</p>Fórmula:C13H19N5O4Cor e Forma:SolidPeso molecular:309.32Vinconate
CAS:<p>Vinconate is an indolonaphthyridine derivative and can stimulate the muscarinic acetylcholine receptor.</p>Fórmula:C18H20N2O2Pureza:98%Cor e Forma:SolidPeso molecular:296.36AT-1001
CAS:<p>AT-1001 is an α3β4 nAChR partial agonist reducing nicotine relapse and withdrawal with negligible impact on food response and dopamine release.</p>Fórmula:C15H21BrN2Cor e Forma:SolidPeso molecular:309.24Rivanicline oxalate
CAS:<p>Rivanicline oxalate is an agonist of neuronal nicotinic receptor, showing high selectivity for the α4β2 subtype (Ki=26 nM).</p>Fórmula:C12H16N2O4Pureza:98%Cor e Forma:SolidPeso molecular:252.27Bradanicline HCl
CAS:<p>Bradanicline(TC-5619) is the agonist of Alpha-7 Nicotinic Receptor.</p>Fórmula:C22H24ClN3O2Cor e Forma:SolidPeso molecular:397.9DREADD agonist 21 dihydrochloride
CAS:<p>DREADD agonist 21 dihydrochloride is a potent human muscarinic acetylcholine M3 receptors ( hM3Dq ) agonist with EC 50 of 1.7 nM [1].</p>Fórmula:C17H20Cl2N4Pureza:98%Cor e Forma:SolidPeso molecular:351.27BPIPP
CAS:<p>guanylyl cyclase (GC) and adenylyl cyclase (AC) inhibitor</p>Fórmula:C22H16BrN3O3Pureza:98%Cor e Forma:SolidPeso molecular:450.28Procyclidine
CAS:<p>Procyclidine is an anticholinergic, muscarinic and NMDA antagonist used in Parkinson's and psychiatric disorder studies.</p>Fórmula:C19H29NOCor e Forma:SolidPeso molecular:287.44Oxybutynin R-isomer HCl
CAS:<p>Aroxybutynin, R-isomer of oxybutynin, is a muscarinic antagonist with antispasmodic effects on bladder muscle, weaker than atropine.</p>Fórmula:C22H32ClNO3Cor e Forma:SolidPeso molecular:393.95VU0455691
CAS:<p>VU0455691 is a selective M1 Muscarinic Receptor Allosteric Modulators.</p>Fórmula:C24H25N5O3SPureza:98%Cor e Forma:SolidPeso molecular:463.55Ambutonium bromide
CAS:<p>Ambutonium bromide is an antagonist of acetylcholine.</p>Fórmula:C20H27BrN2OPureza:98%Cor e Forma:SolidPeso molecular:391.35(±)-Muscarine chloride
CAS:<p>(±)-Muscarine chloride is the racemate of Muscarine chloride. Muscarine is a prototypical agonist for the muscarinic acetylcholine receptor [1] [2].</p>Fórmula:C9H20ClNO2Cor e Forma:SolidPeso molecular:209.71Methapyrilene
CAS:<p>Methapyrilene is a histamine H1 antagonist with sedative action.</p>Fórmula:C14H19N3SCor e Forma:Liquid Physical Description Clear Colorless Liquid (Ntp 1992)Peso molecular:261.39Milameline hydrochloride
CAS:<p>Milameline hydrochloride is a Muscarinic receptor agonist.</p>Fórmula:C8H15ClN2OPureza:98%Cor e Forma:SolidPeso molecular:190.67Cycrimine
CAS:Cycrimine: oral M1 mAChR blocker, lowers acetylcholine, antispasmodic, for Parkinson's and mental disorder studies.Fórmula:C19H29NOCor e Forma:SolidPeso molecular:287.44Parapenzolate bromide
CAS:<p>Parapenzolate bromide is an orally active mAChR antagonist. parapenzolate bromide is an anticholinergic and antitussive agent.</p>Fórmula:C21H26BrNO3Cor e Forma:SolidPeso molecular:420.347DPNB-ABT594
<p>DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates α4β2 over α7 nAChRs; used to study Ca²⁺ signaling in MHb.</p>Fórmula:C31H46ClN3O11Cor e Forma:SolidPeso molecular:672.16AFDX384
CAS:<p>AFDX384 is potent M2/M4 selective antagonist.</p>Fórmula:C28H42N6O5SCor e Forma:SolidPeso molecular:574.74(S)-VQW-765
<p>(S)-VQW-765, oral α7 nAChR partial agonist, may improve cognition in Alzheimer's and schizophrenia.</p>Fórmula:C19H22N2OCor e Forma:SolidPeso molecular:294.39Mazaticol
CAS:<p>Mazaticol: an anticholinergic, blocks muscarinic receptors, inhibits dopamine uptake, used in Parkinson's research.</p>Fórmula:C21H27NO3S2Cor e Forma:SolidPeso molecular:405.57J-104129 fumarate
CAS:<p>J-104129 fumarate is a potent M3 muscarinic receptor antagonist.</p>Fórmula:C28H40N2O6Cor e Forma:SolidPeso molecular:500.63BMS-902483
CAS:<p>BMS-902483: potent α7 partial agonist; enhances rodent cognition; α7 EC50=9.3nM; 5-HT3A IC50=480nM.</p>Fórmula:C18H20N4OPureza:98%Cor e Forma:SolidPeso molecular:308.38RLH 033
CAS:<p>RLH 033 is a selective ligand for the sigma 1 recognition site.</p>Fórmula:C25H31ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:458.98Talsaclidine
CAS:<p>Talsaclidine: full M1 agonist, partial M2/M3 agonist with neuron-stimulating effects.</p>Fórmula:C10H15NOPureza:98%Cor e Forma:SolidPeso molecular:165.23A-85380 HCl
CAS:<p>A-85380 is an agonist of nicotinic acetylcholine receptor.</p>Fórmula:C9H14Cl2N2OCor e Forma:SolidPeso molecular:237.13Phenglutarimid
CAS:<p>Phenglutarimid is an anticholinergic. It is used as an antiparkinsonian agent.</p>Fórmula:C17H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:288.38Pirenzepine
CAS:<p>Pirenzepine targets M1 mAChR, curbs acid secretion, eases spasms, and has anti-cancer properties.</p>Fórmula:C19H21N5O2Cor e Forma:SolidPeso molecular:351.4ENS-163 phosphate
CAS:<p>Ens-163 phosphate is a muscarinic M1 receptor agonist. It is selective.</p>Fórmula:C11H19N2O5PSPureza:98%Cor e Forma:SolidPeso molecular:322.32TMPH hydrochloride
CAS:<p>neuronal nicotinic ACh receptors (nAChRs) antagonist</p>Fórmula:C16H32ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:305.889-CP-Ade Mesylate
CAS:<p>9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.</p>Fórmula:C11H17N5O3SPureza:99.81%Cor e Forma:SolidPeso molecular:299.35Arecaidine but-2-ynyl ester tosylate
CAS:mAChR M2 agonistFórmula:C18H23NO5SPureza:98%Cor e Forma:SolidPeso molecular:365.44GSK575594A
CAS:<p>GSK575594A is a selective agonist of GPR55.</p>Fórmula:C24H23F2N3O3SCor e Forma:SolidPeso molecular:471.52(R)-Oxybutynin
CAS:<p>(R)-Oxybutynin: oral muscarinic blocker with antispasmodic effects, used in neurogenic bladder research.</p>Fórmula:C22H31NO3Cor e Forma:SolidPeso molecular:357.49AC-42
CAS:<p>AC-42 is an allosteric agonist of M1 muscarinic receptor.</p>Fórmula:C20H31NOCor e Forma:SolidPeso molecular:301.47α7 nAchR-JAK2-STAT3 agonist 1
CAS:<p>α7 nAchR-JAK2-STAT3 agonist 1 is a potent inhibitor of the α7 nAchR-JAK2-STAT3 pathway that acts on nitric oxide (NO) (IC50: 0.32 μM).</p>Fórmula:C25H30O6Cor e Forma:SolidPeso molecular:426.5Ethybenztropine
CAS:<p>Ethybenztropine is an anticholinergic used as an antiparkinsonian agent and may also act as a dopamine reuptake inhibitor.</p>Fórmula:C22H27NOPureza:98%Cor e Forma:SolidPeso molecular:321.46Anabasine hydrochloride
CAS:<p>neuronal nicotinic ACh receptor partial agonist</p>Fórmula:C10H15ClN2Pureza:98%Cor e Forma:White To Off-White SolidPeso molecular:198.693Flupyrimin
CAS:<p>Flupyrimin is the insect nicotinic acetylcholine receptor (nAChR) antagonist [1].</p>Fórmula:C13H9ClF3N3OCor e Forma:SolidPeso molecular:315.68Adenylyl cyclase type 2 agonist-1
CAS:<p>Potent AC2 agonist with an EC50 of 90 nM, potential for respiratory disease treatment.</p>Fórmula:C27H17BrClNO5Cor e Forma:SolidPeso molecular:550.78RJR-2403 oxalate
CAS:<p>RJR-2403 oxalate is a highly selective agonist of α4β2 subtype nicotinic receptor.</p>Fórmula:C14H18N2O4Pureza:98%Cor e Forma:SolidPeso molecular:278.308Bibn 140
CAS:<p>Bibn 140 is a highly selective M2 antagonist, it is used to treat Alzheimer's disease and other cognitive disorders.</p>Fórmula:C32H44N4O3Pureza:98%Cor e Forma:SolidPeso molecular:532.72AZD 0328
CAS:<p>AZD 0328 is a nicotinic receptor agonist for α7 neurons.</p>Fórmula:C13H16N2OCor e Forma:SolidPeso molecular:216.28Nelonicline citrate
CAS:<p>Nelonicline citrate (ABT-126) is a selective α7 nAChR agonist with a Ki of 12.3 nM, studied for schizophrenia and Alzheimer's.</p>Fórmula:C23H27N3O8SCor e Forma:SolidPeso molecular:505.54Bradanicline
CAS:<p>Bradanicline: potent α7 nAChR agonist, EC50=17 nM, Ki=1.4 nM, used in cognitive disorder research.</p>Fórmula:C22H23N3O2Cor e Forma:SolidPeso molecular:361.44Asoxime dichloride
CAS:<p>Asoxime dichloride (HI-6) blocks AChRs, including α7 nAChR, and boosts vaccination in the nervous system.</p>Fórmula:C14H16Cl2N4O3Pureza:99.86%Cor e Forma:SolidPeso molecular:359.21Camylofine
CAS:<p>Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle.</p>Fórmula:C19H32N2O2·2HClPureza:98%Cor e Forma:SolidPeso molecular:393.4(Rac)-VU 6008667
CAS:<p>(Rac)-VU 6008667 is a selective M5 NAM with IC50 of 1.8 μM, high CNS penetration.</p>Fórmula:C24H17ClF2N2O2Pureza:99.82%Cor e Forma:SolidPeso molecular:438.85Pentolinium Tartrate
CAS:<p>Pentolinium Tartrate (Pendine) is a nicotinic antagonist that has been used as a ganglionic blocking agent in hypertension.</p>Fórmula:C15H32N2·2C4H5O6Pureza:98%Cor e Forma:SolidPeso molecular:538.6AF-DX 384 free base
CAS:<p>AF-DX 384 free base is an M2 mAChR and M4 mAChR antagonist, useful in research on neurodivisions and diseases such as Parkinson's.</p>Fórmula:C27H38N6O2Pureza:98%Cor e Forma:SolidPeso molecular:478.63Pozanicline
CAS:<p>Pozanicline, a selective α4β2 nAChR partial agonist (Ki=16 nM), may treat nicotine addiction by reversing cognitive deficits.</p>Fórmula:C11H16N2OPureza:98%Cor e Forma:SolidPeso molecular:192.26CB-6673567
CAS:<p>CB-6673567 is a selective inhibitor of adenylyl cyclase.</p>Fórmula:C19H14N4O3Cor e Forma:SolidPeso molecular:346.34NGX-267
CAS:<p>NGX-267, a muscarinic M1 agonist, is used potentially for the treatment of Xerostomia, Alzheimer's disease and cognitive.</p>Fórmula:C10H18N2OSCor e Forma:SolidPeso molecular:214.33Dac 5945
CAS:<p>DAC 5945 is a more effective muscarinic antagonist in the airways than in the heart.</p>Fórmula:C19H30ClN3OPureza:98%Cor e Forma:SolidPeso molecular:351.91Hexocyclium metilsulfate
CAS:<p>Hexocyclium metilsulfate has anti-gastric secretory effects in humans.</p>Fórmula:C21H36N2O5SPureza:98%Cor e Forma:SolidPeso molecular:428.59GS 283
CAS:<p>GS 283 is a Ca(2+) antagonist. GS 283 is also a weak histamine and muscarinic receptor blocker in rat and guinea pig tracheal smooth muscles.</p>Fórmula:C17H17NO3Cor e Forma:SolidPeso molecular:283.32(R)-VU 6008667
CAS:<p>(R)-VU 6008667 is devoid of M5 NAM activity (IC50>10 μM).</p>Fórmula:C24H17ClF2N2O2Cor e Forma:SolidPeso molecular:438.85Anisodine hydrobromide
CAS:<p>Anisodine hydrobromide is an inhibitor of adenosine kinase.</p>Fórmula:C17H22BrNO5Cor e Forma:White Crystals Or Crystalline PowderPeso molecular:400.27Btm 1042
CAS:<p>Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.</p>Fórmula:C21H26ClN3OSCor e Forma:SolidPeso molecular:403.97Hyoscyamine hydrobromide
CAS:<p>Hyoscyamine hydrobromide is an agent of anticholinergic.</p>Fórmula:C17H24BrNO3Pureza:98%Cor e Forma:SolidPeso molecular:370.28Sazetidine A dihydrochloride
CAS:<p>α4β2 nicotinic acetylcholine receptor ligand</p>Fórmula:C15H21ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:296.79FR 121196
CAS:<p>FR 121196, a potential antidementia drug, ameliorates the impaired memory of rat in the Morris water maze.</p>Fórmula:C12H16FN3O3SCor e Forma:SolidPeso molecular:301.34Prifuroline
CAS:<p>Prifuroline is an agent of antiarrhythmic.</p>Fórmula:C14H16N2OPureza:98%Cor e Forma:SolidPeso molecular:228.29Epibatidine 2HCl
CAS:<p>Epibatidine 2HCl is a potent nicotinic agonist.</p>Fórmula:C11H15Cl3N2Pureza:98%Cor e Forma:SolidPeso molecular:281.61Flutropium Bromide
CAS:<p>Flutropium Bromide is a competitive antagonist of acetylcholine. It is used to treat asthma and chronic obstructive pulmonary.</p>Fórmula:C24H29BrFNO3Pureza:98%Cor e Forma:SolidPeso molecular:478.39Vesamicol
CAS:Vesamicol is an experimental drug. It acting presynaptically by inhibiting acetylcholine uptake into synaptic vesicles and reducing its release.Fórmula:C17H25NOPureza:98%Cor e Forma:SolidPeso molecular:259.39Siltenzepine
CAS:<p>Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers.</p>Fórmula:C19H20ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:389.83L 858051
CAS:<p>L 858051 activates adenylate cyclase. It also inhibits glucose transport in rat adipocytes.</p>Fórmula:C29H48N2O7Cor e Forma:SolidPeso molecular:536.7DBO-83
CAS:<p>DBO-83, an agonist of nicotinic acetylcholine receptors (nAChRs), has anti-amnesic and antinociceptive activities.</p>Fórmula:C10H15Cl3N4Pureza:98%Cor e Forma:SolidPeso molecular:297.61ADX-10061
CAS:<p>ADX-10061 is a dopamine D1 receptor antagonist.</p>Fórmula:C19H20N2O4Cor e Forma:SolidPeso molecular:340.37JN403
CAS:<p>JN403 is a selective agonist of nicotinic acetylcholine receptor alpha7.</p>Fórmula:C16H21FN2O2Cor e Forma:SolidPeso molecular:292.35Tebanicline tosylate
CAS:<p>Tebanicline: synthetic, potent, non-opioid analgesic, less toxic than epibatidine; relieves neuropathic pain, acts on α3β4 and α4β2 nicotinic receptors.</p>Fórmula:C16H19ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:370.85Terodiline hydrochloride
CAS:<p>Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),</p>Fórmula:C20H28ClNPureza:98%Cor e Forma:SolidPeso molecular:317.9YM-46303
CAS:<p>YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in</p>Fórmula:C20H23ClN2O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:358.86CHF5407
CAS:<p>CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect on</p>Fórmula:C27H25BrF4N2O3SPureza:>99.99%Cor e Forma:SolidPeso molecular:613.46YM-58790
CAS:<p>YM-58790 is a potent mAChR blocker with Ki values of 28 nM (M1), 260 nM (M2), 15 nM (M3), and reduces bladder contractions in rats.</p>Fórmula:C27H31N3O2Pureza:98.59%Cor e Forma:SoildPeso molecular:429.55Metixene hydrochloride
CAS:<p>Metixene hydrochloride is an anticholinergic antiparkinsonian agent.</p>Fórmula:C20H24ClNSPureza:98%Cor e Forma:SolidPeso molecular:345.93PQCA
CAS:<p>PQCA is a selective M1 receptor modulator with EC50s of 49 nM (monkey) and 135 nM (human), potential for Alzheimer's treatment.</p>Fórmula:C22H20N4O3Pureza:99.88%Cor e Forma:SolidPeso molecular:388.42Penehyclidine hydrochloride
CAS:<p>Penehyclidine hydrochloride: M1/M3 antagonist, activates NF-κB, anti-inflammatory, anticholinergic.</p>Fórmula:C20H30ClNO2Pureza:99.79%Cor e Forma:SolidPeso molecular:351.91PD-102807
CAS:<p>PD-102807 is a selective and competitive M4 muscarinic receptor antagonist for Parkinson's disease research, inhibit airway smooth muscle (ASM) contraction.</p>Fórmula:C23H24N2O4Pureza:98.90%Cor e Forma:SolidPeso molecular:392.45S 24795
CAS:<p>S 24795 (Catestatin acetate(142211-96-9 free base)) is an α7 nAChR partial agonist.</p>Fórmula:C14H13BrINOPureza:99.934%Cor e Forma:SolidPeso molecular:418.07S16961
CAS:<p>S16961 (S169611) is an agonist of nicotinic receptor.</p>Fórmula:C41H71NO6Pureza:99.69%Cor e Forma:SolidPeso molecular:674.01Afacifenacin
CAS:<p>Afacifenacin (SMP-986) fumarate is an M3-selective antagonist for ischemic heart disease and urinary disorders.</p>Fórmula:C27H26F3N3O2Pureza:99.83%Cor e Forma:SolidPeso molecular:481.51UP202-56
CAS:<p>UP202-56 is an adenosinergic agonist and is an adenosine analog.</p>Fórmula:C33H37N7O4Pureza:98%Cor e Forma:SolidPeso molecular:595.69CB-7921220
CAS:<p>CB-7921220 (6-[2-(4-Aminophenyl)vinyl]-2-pyridinecarboxylic acid) is an inhibitor of adenylate cyclase.</p>Fórmula:C14H12N2O2Pureza:99.59%Cor e Forma:SolidPeso molecular:240.26Cimetropium Bromide
CAS:<p>Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.</p>Fórmula:C21H28BrNO4Cor e Forma:SolidPeso molecular:438.36GP531
CAS:<p>GP531, a second-gen adenosine regulator, is inactive at rest but boosts adenosine in ischemia.</p>Fórmula:C16H21N5O4Cor e Forma:SolidPeso molecular:347.37GAT107
CAS:<p>GAT107, a strong α7 nicotinic receptor modulator, aids inflammation and neuropathic pain in mice.</p>Fórmula:C18H17BrN2O2SPureza:99.33%Cor e Forma:SolidPeso molecular:405.31SCH 57790
CAS:<p>SCH 57790: selective muscarinic M2 blocker, boosts acetylcholine & cognition, may treat Alzheimer's.</p>Fórmula:C25H31N3O2SPureza:99% - 99.12%Cor e Forma:SolidPeso molecular:437.6TC-T 6000
CAS:<p>TC-T 6000 (hENT4-IN-1) is an ENT4 inhibitor with vasodilator activity that inhibits hENT1 and hENT2 for the study of cancer and cardiovascular damage.</p>Fórmula:C26H48N8O2Pureza:98.14%Cor e Forma:SolidPeso molecular:504.71Tarafenacin D-tartrate
CAS:<p>Tarafenacin D-tartrate is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.</p>Fórmula:C25H26F4N2O8Pureza:99.86%Cor e Forma:SolidPeso molecular:558.48SIB-1553A hydrochloride
CAS:<p>SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligand</p>Fórmula:C13H20ClNOSPureza:99.56% - 99.73%Cor e Forma:SolidPeso molecular:273.82JNJ-39393406
CAS:<p>JNJ-39393406 is an α7 nicotinic acetylcholine receptor positive allosteric modulator for the study of tobacco dependence and Alzheimer's disease.</p>Fórmula:C19H18F2N6O3Pureza:98.5%Cor e Forma:SolidPeso molecular:416.38PHA 543613
CAS:<p>PHA 543613 is a specific agonist of α7 nAChR (Ki = 8.8 nM) and can be used in studies about the cognitive deficits of Alzheimer's disease and schizophrenia.</p>Fórmula:C15H17N3O2Pureza:99.43% - 99.96%Cor e Forma:SolidPeso molecular:271.31Thonzylamine hydrochloride
CAS:<p>Thonzylamine hydrochloride (Resistab) is an anticholinergic and antihistamine used as an antipruritic.</p>Fórmula:C16H23ClN4OPureza:99.67%Cor e Forma:White Crystalline PowderPeso molecular:322.83Desformylflustrabromine hydrochloride
CAS:<p>Desformylflustrabromine hydrochloride (dFBr hydrochloride) is a selective agonist of nicotinic acetylcholine receptor (nAChR) in α4β2 neurons, with pEC50 of 6.</p>Fórmula:C17H12INO5Pureza:98.12%Cor e Forma:SolidPeso molecular:437.19AQW051
CAS:<p>AQW051 (VQW-765) is an oral α7-nAChR activator for cognitive impairments, used in anxiety disorder studies.</p>Fórmula:C19H22N2OPureza:99.94%Cor e Forma:SolidPeso molecular:294.39PF-03635659
CAS:<p>PF-03635659: potent M3 antagonist, Ki=0.2 nM, long half-life, potential COPD treatment.</p>Fórmula:C28H32N2O3Pureza:98.39% - 99.83%Cor e Forma:SolidPeso molecular:444.57rel-(1R,2R)-Vesamicol Hydrochloride
CAS:<p>Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.</p>Fórmula:C17H26ClNOPureza:99.88%Cor e Forma:SolidPeso molecular:295.85SCH-900271
CAS:<p>SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.</p>Fórmula:C14H16N2O4Pureza:98.82% - 99.93%Cor e Forma:SolidPeso molecular:276.29CP-810123
CAS:<p>CP-810123 is an α7 nAChR agonist used to treat cognitive deficits associated with psychiatric or neurological disorders such as schizophrenia.</p>Fórmula:C14H18N4OPureza:98.63% - 99.60%Cor e Forma:SolidPeso molecular:258.32McN-A 343
CAS:<p>McN-A 343: Selective M1 muscarinic agonist; reduces inflammation in colitis models.</p>Fórmula:C14H18Cl2N2O2Pureza:99.65%Cor e Forma:SolidPeso molecular:317.21Tribendimidine
CAS:<p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>Fórmula:C28H32N6Pureza:≥98%Cor e Forma:SolidPeso molecular:452.59Xanomeline
CAS:<p>Xanomeline: orally active, M1/M4 selective activator for neurological disorders; promising in trials, crosses blood-brain barrier, liver metabolized.</p>Fórmula:C14H23N3OSPureza:99.61%Cor e Forma:SolidPeso molecular:281.42Dimethindene
CAS:<p>Dimethindene (Dimetindeno) is a selective antagonist of H1 receptor and blocks K+ current. Dimethindene exhibits antihistamine and anticholinergic effects.</p>Fórmula:C20H24N2Pureza:98.3% - 98.99%Cor e Forma:SolidPeso molecular:292.42ASM-024
CAS:<p>ASM-024, a synthetic piperazine, activates nicotinic and β2-adrenergic receptors for potential asthma and bronchitis treatment with anti-inflammatory effects.</p>Fórmula:C15H25N2Pureza:99.74%Cor e Forma:SolidPeso molecular:233.37Otenzepad
CAS:<p>Otenzepad (AF-DX 116) is a selective antagonist of M2 mAChR with IC50s of 386 nM and 640 nM for rat heart and rabbit peripheral lung.</p>Fórmula:C24H31N5O2Pureza:99.79%Cor e Forma:SolidPeso molecular:421.54NB001
CAS:<p>NB001 (HTS 09836) is an inhibitor of adenyl cyclase 1 exhibiting effects on neural and non-neural pain.</p>Fórmula:C12H20N6OPureza:99.69%Cor e Forma:Off-White To Pale Pink SolidPeso molecular:264.33Xanomeline oxalate
CAS:<p>Xanomeline oxalate (LY246708), a potent SMRA, boosts phosphoinositide hydrolysis; key for Alzheimer's research.</p>Fórmula:C16H25N3O5SPureza:99.1%Cor e Forma:SolidPeso molecular:371.45NKY80
CAS:<p>NKY80 regulates the adenylyl cyclase catalytic activity in heart and lung tissues.</p>Fórmula:C12H11N3O2Pureza:99.88%Cor e Forma:SolidPeso molecular:229.23Oxotremorine M iodide
CAS:<p>Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.</p>Fórmula:C11H19IN2OPureza:99.57%Cor e Forma:SolidPeso molecular:322.19Iperoxo
CAS:<p>Iperoxo (Iperoxo iodide) is an agonist of Muscarinic AChR and can be used to probe activation-related conformational transitions of muscarinic receptors.</p>Fórmula:C10H17IN2O2Pureza:99.81%Cor e Forma:SolidPeso molecular:324.16Aceclidine
CAS:<p>Aceclidine (1-azabicyclo[2.2.2]octan-3-yl acetate) is a modulator of M3 mAChR and can be used in studies about treating glaucoma by reducing intraocular</p>Fórmula:C9H15NO2Pureza:>99.99%Cor e Forma:SolidPeso molecular:169.22Posatirelin
CAS:<p>Posatirelin, a synthetic peptide, modulates and nourishes brain systems, aiding in vascular dementia research.</p>Fórmula:C17H28N4O4Pureza:98.08% - 98.87%Cor e Forma:SolidPeso molecular:352.43GSK233705
CAS:<p>GSK233705, a muscarinic antagonist, is used to prevent/treat COPD and asthma.</p>Fórmula:C24H29BrN2Pureza:99.87% - 99.98%Cor e Forma:SolidPeso molecular:425.4Temiverine hydrochloride
CAS:<p>Temiverine hydrochloride is a potential calcium channel antagonist with anticholinergic effects that inhibits some of the functions of atropine.</p>Fórmula:C24H36ClNO3Pureza:99.26% - 99.43%Cor e Forma:SolidPeso molecular:422Zamifenacin fumarate
CAS:<p>Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.</p>Fórmula:C31H33NO7Pureza:99.88%Cor e Forma:SolidPeso molecular:531.6LG 50643
CAS:<p>LG 50643 is a muscarinic antagonist.</p>Fórmula:C24H34INO2Pureza:98%Cor e Forma:SolidPeso molecular:495.44LY2033298
CAS:<p>LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.</p>Fórmula:C13H14ClN3O2SPureza:99.06%Cor e Forma:SolidPeso molecular:311.79ICL-CCIC-0019
CAS:<p>ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.</p>Fórmula:C26H44Br2N4Pureza:99.54%Cor e Forma:SolidPeso molecular:572.46PTAC oxalate
CAS:<p>muscarinic receptor ligand</p>Fórmula:C14H21N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:359.46N-Demethyl MK-6884
CAS:<p>N-Demethyl MK-6884 (compound 34) is an M4 mAChR modulator for Alzheimer's and related disease research.</p>Fórmula:C24H23N5OCor e Forma:SolidPeso molecular:397.47Adenylyl cyclase-IN-1
CAS:<p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>Fórmula:C9H8N2S3Cor e Forma:SolidPeso molecular:240.37Tiotropium Bromide hydrate
CAS:<p>Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.</p>Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Cor e Forma:SolidPeso molecular:490.43Timepidium bromide
CAS:<p>Timepidium bromide is an agent of anticholinergic.</p>Fórmula:C17H22BrNOS2Pureza:98%Cor e Forma:SolidPeso molecular:400.4APS3
CAS:<p>APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].</p>Fórmula:C18H7Cl2F6N5O5S2Cor e Forma:SolidPeso molecular:622.31VU0453595
CAS:<p>VU0453595 is a M1 positive allosteric modulator (PAM).</p>Fórmula:C18H15FN4OPureza:99.91%Cor e Forma:SolidPeso molecular:322.34VU 0255035
CAS:<p>VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.</p>Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Cor e Forma:SolidPeso molecular:432.52ABT-418 hydrochloride
CAS:<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Fórmula:C9H15ClN2OCor e Forma:SolidPeso molecular:202.68Muscarine tosylate
CAS:<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Fórmula:C16H27NO5SCor e Forma:SolidPeso molecular:345.45AR420626
CAS:<p>AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.</p>Fórmula:C21H18Cl2N2O3Pureza:98.62%Cor e Forma:SolidPeso molecular:417.29mAChR antagonist 1
CAS:<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Fórmula:C19H22N2O2Cor e Forma:SolidPeso molecular:310.39Homatropine hydrochloride
CAS:<p>Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive</p>Fórmula:C16H22ClNO3Cor e Forma:SolidPeso molecular:311.83-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Fórmula:C11H13BrN2OPureza:99.974%Cor e Forma:SolidPeso molecular:269.14UFP-512
CAS:<p>UFP-512 is a selective delta-opioid (DOP) receptor agonist.</p>Fórmula:C31H33N5O5Pureza:98%Cor e Forma:SolidPeso molecular:555.62A-424274
CAS:<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Fórmula:C14H15N3Pureza:98%Cor e Forma:SolidPeso molecular:225.29L 687306
CAS:<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Fórmula:C11H15N3OCor e Forma:SolidPeso molecular:205.26BMS-933043
CAS:<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Fórmula:C16H19N7OPureza:98%Cor e Forma:SolidPeso molecular:325.37Tematropium
CAS:<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Fórmula:C21H31NO8SPureza:99.89%Cor e Forma:SolidPeso molecular:457.54(-)-Cevimeline hydrochloride hemihydrate
<p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>Fórmula:C10H19ClNO1·5SPureza:98%Cor e Forma:SolidPeso molecular:244.78Lu 26-046
CAS:<p>Lu 26-046 is a muscarinic receptor agonist.</p>Fórmula:C10H12N2OSCor e Forma:SolidPeso molecular:208.28(+)-Sparteine sulfate pentahydrate
<p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>Fórmula:C15H38N2O9SCor e Forma:SolidPeso molecular:422.54(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Fórmula:C10H19ClNO1·5SPureza:98%Cor e Forma:SolidPeso molecular:244.78Dihydro-β-erythroidine hydrobromide
CAS:<p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>Fórmula:C16H22BrNO3Pureza:98%Cor e Forma:White SolidPeso molecular:356.26WIN 62577
CAS:<p>WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.</p>Fórmula:C29H31N3OCor e Forma:SolidPeso molecular:437.576Metoquizine
CAS:<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Fórmula:C22H27N5OPureza:98%Cor e Forma:SolidPeso molecular:377.48(S)-Albuterol
CAS:<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Fórmula:C13H21NO3Cor e Forma:SolidPeso molecular:239.311nAChR antagonist 1
CAS:<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Fórmula:C19H22N4O2Cor e Forma:SolidPeso molecular:338.41,9-Dideoxyforskolin
CAS:<p>The compound is an inactive analog of forskolin(an adenylyl cyclase activator).</p>Fórmula:C22H34O5Pureza:98%Cor e Forma:SolidPeso molecular:378.5LY593093
CAS:<p>LY593093 is a selective partial orthosteric agonist of M1 muscarinic acetylcholine receptor.</p>Fórmula:C32H30FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:507.6CHF-6366
CAS:<p>CHF-6366: M3 antagonist & β2 agonist (pKi 10.4/11.4), mild Ca channel blocker, used in COPD study.</p>Fórmula:C42H48N6O8Cor e Forma:SolidPeso molecular:764.87VU6007496
CAS:<p>VU6007496 is a highly selective and CNS-penetrating M1 positive allosteric modulator (PAM) that exhibits good pharmacokinetics (PK).</p>Fórmula:C25H27N5O2Cor e Forma:SolidPeso molecular:429.51UB 165
CAS:<p>Subtype-selective nicotinic agonist</p>Fórmula:C13H15ClN2Pureza:98%Cor e Forma:SolidPeso molecular:234.72VU6016235
CAS:<p>VU6016235 is a structurally unique, orally available, and highly selective tricyclic M4 muscarinic acetylcholine receptor positive allosteric modulator.</p>Fórmula:C21H22N4OSCor e Forma:SolidPeso molecular:378.49TDI-11861
CAS:<p>TDI-11861 is a second-gen sAC (ADCY10) inhibitor with an IC50 of 5.5 nM and slow dissociation.</p>Fórmula:C22H25ClF2N6O3Cor e Forma:SolidPeso molecular:494.92Dihydro-β-erythroidine
CAS:<p>Dihydro-β-erythroidine, a competitive nicotinic receptor antagonist, effectively blocks the discriminative stimulus properties and inhibits the anxiolytic</p>Fórmula:C16H21NO3Cor e Forma:SolidPeso molecular:275.34TAAR1 agonist 2
CAS:<p>TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.</p>Fórmula:C9H11NOCor e Forma:SolidPeso molecular:149.19VU6005806
CAS:<p>VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.</p>Fórmula:C17H16F3N7O2SPureza:98%Cor e Forma:SolidPeso molecular:439.41AChE/BChE-IN-10
CAS:<p>AChE/BChE-IN-10 inhibits AChE/BChE (IC50: 0.176/0.47 μM), crosses the blood-brain barrier, and prevents Aβ-aggregation.</p>Fórmula:C26H30N2O2Pureza:99.55% - 99.88%Cor e Forma:SoildPeso molecular:402.53MG 624
CAS:<p>neuronal α7 nAChR antagonist</p>Fórmula:C22H30INOCor e Forma:SolidPeso molecular:451.38VU6000918
CAS:<p>VU6000918 is a positive allosteric modulator that targets the muscarinic acetylcholine receptor subtype M4. It exhibits a half maximal effective concentration (EC50) of 19 nM for the human M4 receptor.</p>Fórmula:C18H17F2N5OSCor e Forma:SolidPeso molecular:389.42Lupinine
CAS:<p>Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.</p>Fórmula:C10H19NOPureza:99.95%Cor e Forma:SolidPeso molecular:169.26Oxitropium Bromide
CAS:<p>Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.</p>Fórmula:C19H26BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:412.32
