AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 575 produtos de "AChR"
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VU0357017 hydrochloride
CAS:<p>VU0357017 hydrochloride (ML071 hydrochloride) is highly selective M1 agonists act at an allosteric site to activate the receptor (EC50: 477 ± 172 nM; Pec50: 6.</p>Fórmula:C18H28ClN3O3Pureza:99% - 99.97%Cor e Forma:SolidPeso molecular:369.89Piperidolate hydrochloride
CAS:<p>Piperidolate hydrochloride, an antimuscarinic, reduces acetylcholine-induced intestinal spasms in rats and dogs.</p>Fórmula:C21H26ClNO2Pureza:99.5%Cor e Forma:SolidPeso molecular:359.89KH7
CAS:<p>KH7 is a soluble inhibitor of adenylyl cyclase (sAC)-specific.</p>Fórmula:C17H15BrN4O2SPureza:98.43%Cor e Forma:SolidPeso molecular:419.3Batefenterol
CAS:<p>Batefenterol (GSK961081) is a muscarinic antagonist and β2-agonist with high affinity (Ki: 1.4/1.3/3.7 nM).</p>Fórmula:C40H42ClN5O7Pureza:97.94% - 98.4%Cor e Forma:SolidPeso molecular:740.24Dicyclomine
CAS:<p>Dicyclomine: oral muscarinic antagonist, eases GI muscle spasms, high affinity for M1/M2 receptors, Ki of 5.1 nM/54.6 nM.</p>Fórmula:C19H35NO2Cor e Forma:SolidPeso molecular:309.49Tebanicline hydrochloride
CAS:<p>Tebanicline hydrochloride (Ebanicline hydrochloride) , is an effective synthetic nicotinic (non-opioid) analgesic drug.</p>Fórmula:C9H12Cl2N2OPureza:91.74% - 98.71%Cor e Forma:SolidPeso molecular:235.11TBPB
CAS:<p>TBPB is an allosteric M1 mAChR agonist.</p>Fórmula:C25H32N4OPureza:97.87% - 99.9%Cor e Forma:SolidPeso molecular:404.559-Ethyladenine
CAS:<p>9-Ethyladenine (6-Amino-9-ethylpurine) is a partially potent APRT (adenine phosphoribosyltransferase) inhibitor [1].</p>Fórmula:C7H9N5Pureza:99.35% - 99.41%Cor e Forma:SolidPeso molecular:163.18suvn-911
CAS:<p>suvn-911 is a potent and selective antagonist of neuronal nicotinic acetylcholine α4β2 receptor (Ki = 1.5 nM) with antidepressant activity.</p>Fórmula:C11H14Cl2N2OPureza:98.88%Cor e Forma:SolidPeso molecular:261.15Atracurium besylate
CAS:<p>Atracurium besylate (51W89) is a short-acting, non-depolarizing muscle relaxant, not affecting the heart or reliant on kidneys.</p>Fórmula:C65H82N2O18S2Pureza:98.94% - 99.71%Cor e Forma:SolidPeso molecular:1243.49A 582941 HCl (848591-90-2(free base))
<p>A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties</p>Fórmula:C17H21ClN4Pureza:99.83%Cor e Forma:SolidPeso molecular:316.834BP-TQS
CAS:<p>4BP-TQS is an allosteric agonist of α7 nAChRs.</p>Fórmula:C18H17BrN2O2SPureza:99.96%Cor e Forma:SolidPeso molecular:405.31Imidafenacin
CAS:<p>Imidafenacin (KRP-197)(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM.</p>Fórmula:C20H21N3OPureza:99.17%Cor e Forma:SolidPeso molecular:319.4Brompheniramine
CAS:<p>Brompheniramine, an alkylamine antihistamine, targets H1 receptors (Kd=6.06nM) and has anticholinergic/depressant qualities. Blocks Ca/Na/hERG channels.</p>Fórmula:C16H19BrN2Cor e Forma:SolidPeso molecular:319.24Varenicline dihydrochloride
CAS:<p>Varenicline dihydrochloride is a Selective α4β2 nicotinic acetylcholine receptor partial agonist.</p>Fórmula:C13H15Cl2N3Pureza:99.88% - 99.97%Cor e Forma:SolidPeso molecular:284.18SEN12333
CAS:<p>SEN12333 is an α7 nicotinic acetylcholine receptor (nAChR) agonist</p>Fórmula:C20H25N3O2Pureza:99.02%Cor e Forma:SolidPeso molecular:339.43Ilmetropium iodide
CAS:<p>Ilmetropium iodide is a bronchodilator.</p>Fórmula:C20H30INO3Pureza:98.45%Cor e Forma:SolidPeso molecular:459.36Ursulcholic acid
CAS:<p>Ursulcholic acid (Ursulcholic) is a water-soluble anticholinergic compound.</p>Fórmula:C24H40O10S2Pureza:98%Cor e Forma:SolidPeso molecular:552.7Pirmenol
CAS:<p>Pirmenol is a new antiarrhythmic drug</p>Fórmula:C22H30N2OPureza:97.24%Cor e Forma:SolidPeso molecular:338.49Darifenacin
CAS:<p>Darifenacin (UK-88525) is a muscarinic receptor M3 antagonist with anticonvulsant activity and can be used to study urinary incontinence and overactive bladder.</p>Fórmula:C28H30N2O2Pureza:99.78%Cor e Forma:SolidPeso molecular:426.55LY2119620
CAS:<p>LY2119620 is a specific, and allosteric agonist of human M2 and M4 muscarinic acetylcholine receptors.</p>Fórmula:C19H24ClN5O3SPureza:99.7%Cor e Forma:SolidPeso molecular:437.94Benzetimide hydrochloride
CAS:<p>Benzetimide hydrochloride (R4929) is an antagonist of muscarinic acetylcholine receptor.treatment neuroleptic-induced parkinsonism.</p>Fórmula:C23H27ClN2O2Pureza:99.32%Cor e Forma:Off-White PowderPeso molecular:398.93Oxyphencyclimine
CAS:<p>Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers.</p>Fórmula:C20H28N2O3Cor e Forma:SolidPeso molecular:344.45Aclidinium bromide
CAS:<p>Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis.</p>Fórmula:C26H30NO4S2·BrPureza:99.53% - 99.69%Cor e Forma:SolidPeso molecular:564.55Coluracetam
CAS:<p>Coluracetam (MKC-231)(MKC-231) is a Choline Uptake Enhancer.</p>Fórmula:C19H23N3O3Pureza:99.96%Cor e Forma:SolidPeso molecular:341.4Mecamylamine hydrochloride
CAS:<p>Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.</p>Fórmula:C11H22ClNPureza:99.76% - >99.99%Cor e Forma:White SolidPeso molecular:203.75Rivanicline hemioxalate
<p>Rivanicline hemioxalate is a selective α4β2 nicotinic receptor agonist (K i =26 nM), over 1,000x preference to α7 (K i =3.6 μM), with limited side effects.</p>Fórmula:C12H16N2O4Pureza:98%Cor e Forma:SolidPeso molecular:207.23BQCA
CAS:<p>BQCA (benzylquinolone carboxylic acid) a highly selective allosteric M1 mAChR modulator.</p>Fórmula:C18H15NO4Pureza:97.22%Cor e Forma:SolidPeso molecular:309.32Oxyphencyclimine Hydrochloride
CAS:<p>Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities.</p>Fórmula:C20H29ClN2O3Pureza:99.55%Cor e Forma:SolidPeso molecular:380.91Propantheline
CAS:<p>Propantheline: oral muscarinic receptor blocker for smooth muscle issues, hyperhidrosis, and bladder control.</p>Fórmula:C23H30NO3Cor e Forma:SolidPeso molecular:368.49Encenicline
CAS:<p>Encenicline (EVP-6124), a selective α7 nAChRs agonist, targets cognitive impairment in schizophrenia and Alzheimer's.</p>Fórmula:C16H17ClN2OSPureza:99.20%Cor e Forma:SolidPeso molecular:320.84Propiverine
CAS:<p>Propiverine reduces muscle spasms by limiting calcium influx, targeting bladder smooth muscles, aiding OAB research.</p>Fórmula:C23H29NO3Cor e Forma:SolidPeso molecular:367.48JHU37160
CAS:JHU37160 is a DREADD agonist with Ki of 1.9 nM for hM3Dq, 3.6 nM for hM4Di, and EC50 of 18.5 nM (hM3Dq), 0.2 nM (hM4Di) in HEK-293 cell assays.Fórmula:C19H20ClFN4Pureza:99.87%Cor e Forma:SolidPeso molecular:358.84OXOMEMAZINE
CAS:<p>Oxomemazine: a phenothiazine antihistamine H1-blocker with strong antimuscarinic and selective M1 antagonist properties, used in cough research.</p>Fórmula:C18H22N2O2SPureza:99.58%Cor e Forma:SolidPeso molecular:330.44Mecamylamine
CAS:<p>Mecamylamine: oral, noncompetitive nAChR blocker, crosses blood-brain barrier, for neuropsychiatric and hypertension research.</p>Fórmula:C11H21NCor e Forma:SolidPeso molecular:167.29Methylbenactyzium Bromide
CAS:<p>Methylbenactyzium Bromide (Semulgin) is an anticonvulsant that is the active metabolite of trimethadione.</p>Fórmula:C21H28BrNO3Pureza:99.29%Cor e Forma:SolidPeso molecular:422.36Solifenacin hydrochloride
CAS:<p>Solifenacin Hcl is a muscarinic receptor antagonist.</p>Fórmula:C23H27ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:398.93Donepezil Hydrochloride
CAS:<p>Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).</p>Fórmula:C24H29NO3·HClPureza:99.55% - 99.8%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:415.96Isopropamide Iodide
CAS:<p>Isopropamide iodide: long-acting anticholinergic, treats peptic ulcers, GI disorders, Alzheimer's.</p>Fórmula:C23H33IN2OPureza:99.67%Cor e Forma:SolidPeso molecular:480.43SQ22536
CAS:<p>SQ22536, a tetrahydrofuryl adenosine analogue, inhibits adenylate cyclase in catfish and rat hepatocytes non-competitively.</p>Fórmula:C9H11N5OPureza:99.18%Cor e Forma:Off-White SolidPeso molecular:205.22ML380
CAS:<p>ML380 is a highly potent and the first CNS penetrant M5 positive allosteric modulator (PAM).</p>Fórmula:C23H25F3N4O3SPureza:99.69%Cor e Forma:SolidPeso molecular:494.53VU0467154
CAS:<p>VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor.</p>Fórmula:C17H15F3N4O3S2Pureza:98.28% - 99.51%Cor e Forma:SolidPeso molecular:444.45VU0152100
CAS:<p>VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM).</p>Fórmula:C18H19N3O2SPureza:99.56%Cor e Forma:SolidPeso molecular:341.43Ipratropium Bromide
CAS:<p>Ipratropium Bromide (Sch 1000) is an antagonist of muscarinic receptors and is used in COPD and asthma studies.</p>Fórmula:C20H30BrNO3Pureza:99.92%Cor e Forma:SolidPeso molecular:412.37VU0119498
CAS:<p>VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.</p>Fórmula:C15H10BrNO2Pureza:97.56%Cor e Forma:SolidPeso molecular:316.15Succinylcholine Chloride Dihydrate
CAS:<p>Succinylcholine Chloride Dihydrate (Succinyldicholine dichloride) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.</p>Fórmula:C14H30N2O4·2Cl·2H2OPureza:99.87%Cor e Forma:White SolidPeso molecular:397.34VU10010
CAS:<p>VU10010 (VU 10010) is allosteric potentiator of M4 acetylcholine receptors.</p>Fórmula:C17H16ClN3OSPureza:99.36%Cor e Forma:SolidPeso molecular:345.85Procyclidine hydrochloride
CAS:<p>Procyclidine hydrochloride ((±)-Procyclidine hydrochlorid) is a potent anticholinergic agent and also have NMDA antagonist properties.</p>Fórmula:C19H30ClNOPureza:99.24% - 99.88%Cor e Forma:Crystals From Petroleum Ether White PowderPeso molecular:323.9Oxotremorine sesquifumarate
CAS:<p>Oxotremorine sesquifumarate is a muscarinic agonist.</p>Fórmula:C12H18N2OC4H4O4Pureza:97.94%Cor e Forma:SolidPeso molecular:380.39TQS
CAS:<p>TQS (4-Naphthalen-1-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) is a positive allosteric modulator of α7 nACh receptors.</p>Fórmula:C22H20N2O2SPureza:98.56%Cor e Forma:SolidPeso molecular:376.47
