AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 609 produtos para "AChR".
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SIB-1553A hydrochloride
CAS:SIB-1553A hydrochloride is a nicotinic acetylcholine receptor agonist and a selective neuronal nAChR ligandFórmula:C13H20ClNOSPureza:99.71% - 99.89%Cor e Forma:Yellow SolidPeso molecular:273.82Terodiline hydrochloride
CAS:Terodiline hydrochloride is an antagonist of M1-selective muscarinic receptor (mAChR)(Kbs of 15, 160, 280, and 198 nM in rabbit vas deferens (M1), atria (M2),Fórmula:C20H28ClNPureza:98%Cor e Forma:SolidPeso molecular:317.9YM-46303
CAS:YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia inFórmula:C20H23ClN2O2Pureza:>99.99%Cor e Forma:Yellow SolidPeso molecular:358.86CHF5407
CAS:CHF5407（SVT-47060） is a potent and selective muscarinic M3 receptor antagonist with prolonged action at muscarinic receptors.CHF5407 has an effect onFórmula:C27H25BrF4N2O3SPureza:99.54% - >99.99%Cor e Forma:White SolidPeso molecular:613.46T761-0184
CAS:T761-0184 is a potent antagonist of α7 nicotinic receptor (nAChR) [1].Fórmula:C16H20FN3OCor e Forma:SolidPeso molecular:289.35KL8604166
CAS:KL8604166 (UCB-11056) is a potential puzzle compound.UCB-11056 amplifies the formation of inducible cyclic AMP in rat brain tissue.Fórmula:C12H21N5O2Pureza:99.95%Cor e Forma:White SolidPeso molecular:267.33PF-06767832
CAS:PF-06767832: selective M1 PAM (EC50=60 nM), no M2-M5 activity, good CNS penetration, but has GI and cardiovascular risks.Fórmula:C22H23N3O3SCor e Forma:SolidPeso molecular:409.5Hadacidin
CAS:Hadacidin is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Fórmula:C3H5NO4Cor e Forma:SolidPeso molecular:119.08Glucagon Receptor Antagonist I
CAS:Glucagon antagonist I blocks the GCGR (IC50=181 nM), stops glucagon-induced glycogenolysis, and lowers glucose in glucagon-treated humanized mice.Fórmula:C20H30N2OSCor e Forma:SolidPeso molecular:346.53Telenzepine
CAS:Telenzepine is a potent and selective M1 antimuscarinic.Fórmula:C19H22N4O2SPureza:98%Cor e Forma:SolidPeso molecular:370.47RJR-2429
CAS:RJR-2429 is a potent AChR agonist.Fórmula:C12H16N2Cor e Forma:SolidPeso molecular:188.27Hadacidin sodium
CAS:Hadacidin sodium is an inhibitor of AMP synthesis. Hadacidin and hadacidin analogues have anticancer activity and activity against adenylosuccinate synthetase.Fórmula:C3H4NNaO4Cor e Forma:SolidPeso molecular:141.06Dexetimide HCl
CAS:Dexetimide HCl is a muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.Fórmula:C23H27ClN2O2Cor e Forma:SolidPeso molecular:398.93(E/Z)-VU0029767
CAS:VU0029767 enhances M1 muscarinic receptor function, increasing acetylcholine potency and efficacy.Fórmula:C21H21N3O3Cor e Forma:SolidPeso molecular:363.41Octamylamine sulfamate
CAS:Octamylamine sulfamate is a P450 inhibitor.Fórmula:C13H32N2O3SCor e Forma:SolidPeso molecular:296.47AC260584
CAS:AC260584 is an M1 muscarinic receptor allosteric agonist (pEC50: 7.6).Fórmula:C20H29FN2O2Cor e Forma:SolidPeso molecular:348.45Neramexane Mesylate
CAS:Neramexane: NMDA & nicotinic receptor blocker with neuroprotective, antidepressant, and cognitive-enhancing effects.Fórmula:C12H27NO3SPureza:98%Cor e Forma:SolidPeso molecular:265.41Metanicotine
CAS:Metanicotine is a selective nicotinic agonist with antinociceptive properties.Fórmula:C10H14N2Cor e Forma:SolidPeso molecular:162.23Caramiphen hydrochloride
CAS:Caramiphen hydrochloride: antimuscarinic, anticholinergic, NMDA receptor antagonist salt.Fórmula:C18H28ClNO2Cor e Forma:SolidPeso molecular:325.88Muscarine chloride
CAS:Muscarine chloride is a toxic alkaloid found in Amanita muscaria and other fungi of the Inocybe species.Fórmula:C9H20ClNO2Cor e Forma:SolidPeso molecular:209.71
