AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 575 produtos de "AChR"
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ABT-418 hydrochloride
CAS:<p>ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.</p>Fórmula:C9H15ClN2OCor e Forma:SolidPeso molecular:202.68Muscarine tosylate
CAS:<p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>Fórmula:C16H27NO5SCor e Forma:SolidPeso molecular:345.45AR420626
CAS:<p>AR420626: selective FA3R agonist, guards against SALS, effects blocked by BHB, a FA3R antagonist.</p>Fórmula:C21H18Cl2N2O3Pureza:98.62%Cor e Forma:SolidPeso molecular:417.29mAChR antagonist 1
CAS:<p>Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,</p>Fórmula:C19H22N2O2Cor e Forma:SolidPeso molecular:310.39Homatropine hydrochloride
CAS:<p>Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussive</p>Fórmula:C16H22ClNO3Cor e Forma:SolidPeso molecular:311.83-Bromocytisine
CAS:<p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>Fórmula:C11H13BrN2OPureza:99.974%Cor e Forma:SolidPeso molecular:269.14UFP-512
CAS:<p>UFP-512 is a selective delta-opioid (DOP) receptor agonist.</p>Fórmula:C31H33N5O5Pureza:98%Cor e Forma:SolidPeso molecular:555.62A-424274
CAS:<p>A-424274 is a positive allosteric modulator of α4β2 neuronal nicotinic receptor.</p>Fórmula:C14H15N3Pureza:98%Cor e Forma:SolidPeso molecular:225.29L 687306
CAS:<p>L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.</p>Fórmula:C11H15N3OCor e Forma:SolidPeso molecular:205.26BMS-933043
CAS:<p>BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).</p>Fórmula:C16H19N7OPureza:98%Cor e Forma:SolidPeso molecular:325.37Tematropium
CAS:<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Fórmula:C21H31NO8SPureza:99.89%Cor e Forma:SolidPeso molecular:457.54(-)-Cevimeline hydrochloride hemihydrate
<p>(-)-Cevimeline HCl hemihydrate, a muscarinic agonist, treats Sjogren's xerostomia. Quick absorption, species-dependent metabolism.</p>Fórmula:C10H19ClNO1·5SPureza:98%Cor e Forma:SolidPeso molecular:244.78Lu 26-046
CAS:<p>Lu 26-046 is a muscarinic receptor agonist.</p>Fórmula:C10H12N2OSCor e Forma:SolidPeso molecular:208.28(+)-Sparteine sulfate pentahydrate
<p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>Fórmula:C15H38N2O9SCor e Forma:SolidPeso molecular:422.54(+)-Cevimeline hydrochloride hemihydrate
<p>(+)-Cevimeline HCl hemihydrate is a muscarinic agonist for dry mouth in Sjogren's with rapid absorption, differing metabolism in species.</p>Fórmula:C10H19ClNO1·5SPureza:98%Cor e Forma:SolidPeso molecular:244.78Dihydro-β-erythroidine hydrobromide
CAS:<p>Dihydro-β-erythroidine hydrobromide(DHβE) is a potent, oral active and competitive antagonist of neuronal nicotinic acetylcholine receptors (nAChRs).</p>Fórmula:C16H22BrNO3Pureza:98%Cor e Forma:White SolidPeso molecular:356.26WIN 62577
CAS:<p>WIN 62577 is a species-selective tachykinin NK1 receptor antagonist and also serves as an allosteric enhancer with micromolar potency at M3 receptors. Additionally, WIN 62577 demonstrates potent antiviral activity against SARS-CoV-2.</p>Fórmula:C29H31N3OCor e Forma:SolidPeso molecular:437.576Metoquizine
CAS:<p>Metoquizine is an anticholinergic compound. It is a muscarinic acetylcholine receptor antagonist that has been used to treat ulcers.</p>Fórmula:C22H27N5OPureza:98%Cor e Forma:SolidPeso molecular:377.48(S)-Albuterol
CAS:<p>(S)-Albuterol functions as a muscarinic receptor and phospholipase C activator, enhancing the intracellular free calcium concentration in airway smooth muscle cells.</p>Fórmula:C13H21NO3Cor e Forma:SolidPeso molecular:239.311nAChR antagonist 1
CAS:<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Fórmula:C19H22N4O2Cor e Forma:SolidPeso molecular:338.4
