AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 636 produtos de "AChR"
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Oxotremorine M iodide
CAS:Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.Fórmula:C11H19IN2OPureza:99.57%Cor e Forma:SolidPeso molecular:322.19mAChR antagonist 1
CAS:Compound 4a, a mAChR antagonist, exhibits K i values of 255 nM for M1 and M5 subtypes, and lower values of 121 nM and 158 nM for M3 and M4 subtypes,Fórmula:C19H22N2O2Cor e Forma:SolidPeso molecular:310.39Cynandione A
CAS:Cynandione A is an acetophenone derived from Cynanchum wilfordii with anti-inflammatory activity.Fórmula:C16H14O6Pureza:99.62%Cor e Forma:SolidPeso molecular:302.28Tiotropium Bromide hydrate
CAS:Tiotropium Bromide hydrate is a potent, long-lasting anticholinergic bronchodilator for COPD, with high affinity for muscarinic receptors M1, M2, and M3.Fórmula:C19H24BrNO5S2Pureza:98.44% - 99.41%Cor e Forma:SolidPeso molecular:490.43ASP8302
CAS:ASP8302 is an allosteric potentiator of the muscarinic M3 receptor. It enhances urination efficiency and reduces residual urine volume in two rat models of voiding dysfunction. ASP8302 is useful for investigating diseases associated with bladder dysfunction.Fórmula:C26H32ClN7O3S2Cor e Forma:SolidPeso molecular:590.16ICL-CCIC-0019
CAS:ICL-CCIC-0019 inhibits ChoKα, causes G1 arrest, ER stress, and cancer cell apoptosis.Fórmula:C26H44Br2N4Pureza:99.54%Cor e Forma:SolidPeso molecular:572.46Ref: TM-T27579
2mg46,00€5mg73,00€10mg96,00€25mg139,00€50mg212,00€100mg363,00€200mg533,00€1mL*10mM (DMSO)93,00€APS3
CAS:APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].Fórmula:C18H7Cl2F6N5O5S2Cor e Forma:SolidPeso molecular:622.31PTAC oxalate
CAS:muscarinic receptor ligandFórmula:C14H21N3O4S2Pureza:98%Cor e Forma:SolidPeso molecular:359.46Zamifenacin fumarate
CAS:Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor.Fórmula:C31H33NO7Pureza:99.88%Cor e Forma:SolidPeso molecular:531.6Ref: TM-T13385
2mg34,00€5mg50,00€10mg75,00€25mg128,00€50mg200,00€100mg304,00€200mg424,00€1mL*10mM (DMSO)58,00€ABT-418 hydrochloride
CAS:ABT-418 HCl enhances cognition and reduces anxiety as a selective nAChRs agonist, researched for Alzheimer's.Fórmula:C9H15ClN2OCor e Forma:SolidPeso molecular:202.68Adenylyl cyclase-IN-1
CAS:Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].Fórmula:C9H8N2S3Cor e Forma:SolidPeso molecular:240.37LG 50643
CAS:LG 50643 is a muscarinic antagonist.Fórmula:C24H34INO2Pureza:98%Cor e Forma:SolidPeso molecular:495.443-Bromocytisine
CAS:3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).Fórmula:C11H13BrN2OPureza:99.974%Cor e Forma:SolidPeso molecular:269.14Ref: TM-T10108
1mg95,00€5mg202,00€10mg293,00€25mg494,00€50mg710,00€100mg973,00€200mg1.305,00€1mL*10mM (DMSO)178,00€VU 0255035
CAS:VU 0255035 is a highly selective, competitive and brain penetrant muscarinic M1 receptor antagonist with an IC50 of 130 nM.
Fórmula:C18H20N6O3S2Pureza:98.09% - 98.1%Cor e Forma:SolidPeso molecular:432.52Tolterodine Dimer
CAS:Tolterodine Dimer is a derivative of Tolterodine -- a muscarinic receptor antagonist that is used to treat patients with overactive bladder.Fórmula:C35H41NO2Cor e Forma:SolidPeso molecular:507.71BMS-933043
CAS:BMS-933043: α7 nAChR partial agonist, binds rat (Ki=3.3 nM) & human (Ki=8.1 nM), agonist with EC50=23.4 nM (calcium assay), 0.14-0.29 μM (electrophysiology).Fórmula:C16H19N7OPureza:98%Cor e Forma:SolidPeso molecular:325.37Homatropine hydrochloride
CAS:Homatropine hydrochloride is an orally active anticholinergic agent that induces rapid pupil dilation with cycloplegic effects and possesses antitussiveFórmula:C16H22ClNO3Cor e Forma:SolidPeso molecular:311.8L 687306
CAS:L 687306 is a partial agonist of muscarinic M1 receptors. It is also a highly competitive antagonist at cardiac M2 receptors and ileal M3 muscarinic receptors.Fórmula:C11H15N3OCor e Forma:SolidPeso molecular:205.26LY2033298
CAS:LY2033298 enhances oximoline's effect on hamster circadian rhythms, aiding neurosystem disorders.Fórmula:C13H14ClN3O2SPureza:98.78%Cor e Forma:SolidPeso molecular:311.79Timepidium bromide
CAS:Timepidium bromide is an agent of anticholinergic.Fórmula:C17H22BrNOS2Pureza:98%Cor e Forma:SolidPeso molecular:400.4
