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NMDAR

NMDAR

Os inibidores do receptor N-Metil-D-Aspartato (NMDAR) são compostos que bloqueiam a atividade dos NMDARs, um subtipo de receptores de glutamato que desempenham um papel crucial na plasticidade sináptica, no aprendizado e na memória. A superativação dos NMDARs está implicada na excitotoxicidade, que pode levar a danos neuronais e está associada a condições como AVC, lesão cerebral traumática e doenças neurodegenerativas. Os inibidores de NMDAR são ferramentas essenciais para estudar a excitotoxicidade e desenvolver terapias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de NMDAR para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.

Foram encontrados 15 produtos para "NMDAR".

  • SDZ 220-040 ammonium
    Targetmol
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    SDZ 220-040 ammonium

    SDZ 220-040 ammonium is a competitive glutamate ionotropic receptor NMDA antagonist used in the study of neurological disorders.
    Fórmula:C16H19Cl2N2O6P
    Pureza:99.93%
    Cor e Forma:White Solid
    Peso molecular:437.21

    Ref: TM-T23344L

  • FP802 2HCl
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    FP802 2HCl

    CAS:
    FP802 2HCl is an orally active TwinF interface inhibitor, neuroprotective, disrupts the toxicity of the NMDAR/TRPM4 death complex.
    Fórmula:C11H19Cl3N2
    Pureza:98%
    Peso molecular:285.64

    Ref: TM-TYD-02816

  • NT 13 acetate
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    NT 13 acetate

    NT 13 acetate is a partial agonist of NMDA receptor and can be used for research on depression, anxiety, and other related diseases.
    Fórmula:C20H34N4O9
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:474.51

    Ref: TM-TP1023L

  • S1R agonist 2
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    S1R agonist 2

    CAS:
    S1R agonist 2 is a selective S1R agonist with a Ki of 88 nM for S2R and 1.1 nM for S1R and is protective against ROS and NMDA-induced neurotoxicity.
    Fórmula:C21H27NO
    Pureza:99.66%
    Cor e Forma:Solid
    Peso molecular:309.4452

    Ref: TM-T72059

  • EVT-101 free base
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    EVT-101 free base

    CAS:
    EVT-101 free base (ENS-101) NR2B NMDA receptor antagonist for neuropharmacology, depression research, glutamatergic signaling and CNS pathway studies.
    Fórmula:C16H13F3N4
    Cor e Forma:Solid
    Peso molecular:318.30

    Ref: TM-T68973

  • SDZ 220-581 hydrochloride
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    SDZ 220-581 hydrochloride

    CAS:
    SDZ 220-581 hydrochloride is a potent competitive NMDA receptor antagonist (pKᵢ = 7.7) with good oral bioavailability.
    Fórmula:C16H18Cl2NO5P
    Pureza:98%
    Cor e Forma:White Solid
    Peso molecular:406.20

    Ref: TM-T12889L

  • Flupirtine maleate
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    Flupirtine maleate

    CAS:
    Flupirtine maleate (Katadolon maleate), a centrally acting non-opioid analgesia, is the salt form of Flupirtine. Flupirtine is an NMDA receptor antagonist.
    Fórmula:C15H17FN4O2·C4H4O4
    Pureza:99.5% - 99.9%
    Cor e Forma:Yellow Solid
    Peso molecular:420.39

    Ref: TM-T6504

  • CNS-5161
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    CNS-5161

    CAS:
    CNS-5161 is a selective, non-competitive NMDA receptor antagonist that primarily targets the GluN2B subunit.
    Fórmula:C16H18ClN3S2
    Pureza:99.61%
    Cor e Forma:Solid
    Peso molecular:351.92

    Ref: TM-T27055

  • TCN 201
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    TCN 201

    CAS:
    TCN 201 is a selective antagonist of NMDA receptors containing the NR2A subunit.
    Fórmula:C21H17ClFN3O4S
    Pureza:98.5%
    Cor e Forma:Solid
    Peso molecular:461.894

    Ref: TM-T7870

  • Glypromate acetate
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    Glypromate acetate

    Glypromate acetate is a neuroprotective agent, is a weak NMDA receptor agonist.
    Fórmula:C14H23N3O8
    Pureza:99.94%
    Cor e Forma:Solid
    Peso molecular:361.35

    Ref: TM-T7778L

  • Perzinfotel
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    Perzinfotel

    CAS:
    Perzinfotel is a selective NMDA antagonist; IC50=34 nM; neuroprotective agent; used for stroke and pain research.
    Fórmula:C9H13N2O5P
    Pureza:98.35%
    Cor e Forma:Yellow Solid
    Peso molecular:260.18

    Ref: TM-T16473

  • Pregnanolone sulfate (pyridinium)
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    Pregnanolone sulfate (pyridinium)

    CAS:
    Pregnanolone sulfate pyridinium, an endogenous neurosteroid, inhibits NMDA receptors and exhibits neuroprotective properties [1].
    Fórmula:C26H39NO5S
    Pureza:98%
    Cor e Forma:White Solid
    Peso molecular:477.657

    Ref: TM-T81409

  • R-(+)-EU-1180-453
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    R-(+)-EU-1180-453

    CAS:
    R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.
    Fórmula:C22H21FN2O3
    Pureza:99.88%
    Cor e Forma:Solid
    Peso molecular:380.41

    Ref: TM-T69611

  • BMS-986163
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    BMS-986163

    CAS:
    BMS-986163, GluN2B negative allosteric modulator prodrug, converts to BMS-986169 (Ki=4 nM), antidepressant-like activity.
    Fórmula:C23H28FN2O5P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:462.45

    Ref: TM-T14686

  • Blixeprodil
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    Blixeprodil

    CAS:
    Blixeprodil (GM-1020) is an oral NMDA antagonist (Ki=3.25 µM, IC₅₀=1.192 µM) that crosses the BBB and shows antidepressant effects.
    Fórmula:C13H16FNO
    Pureza:>99.99%
    Cor e Forma:Solid
    Peso molecular:221.27

    Ref: TM-T206599