PAI-1
O Plasminogen Activator Inhibitor-1 (PAI-1) é um inibidor de serina protease que regula a fibrinólise ao inibir o ativador de plasminogênio tecidual (tPA) e a uroquinase (uPA). Níveis elevados de PAI-1 estão associados a um aumento do risco de trombose, doenças cardiovasculares e síndrome metabólica. Inibidores de PAI-1 estão sendo investigados por seu potencial no tratamento dessas condições. Na CymitQuimica, oferecemos inibidores de PAI-1 para apoiar sua pesquisa em hematologia, saúde cardiovascular e doenças metabólicas.
Foram encontrados 27 produtos para "PAI-1".
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Upamostat
CAS:Upamostat is an inhibitor of a serine protease and is a urokinase plasminogen activator (uPA) inhibitor.Fórmula:C32H47N5O6SPureza:99.41%Cor e Forma:White SolidPeso molecular:629.81Ref: TM-T13257
1mg60,00€2mg89,00€5mg138,00€1mL*10mM (DMSO)155,00€10mg215,00€25mg359,00€50mg510,00€100mg692,00€Angstrom6
CAS:Angstrom6 (A-6 peptide) is an 8 amino acid peptide derived from single chain urokinase fibrinogen activator (scuPA) that interferes with the uPA/uPAR cascadeFórmula:C39H62N10O15Pureza:99.97%Cor e Forma:SolidPeso molecular:910.97CT140
CT140 is a human IgG4 monoclonal antibody (mAb) that specifically targets PAI-1. The suggested isotype control for this compound is Human IgG4 kappa, Isotype Control.Cor e Forma:Odour LiquidGGACK hydrochloride
GGACK (H-Glu-Gly-Arg-CMK) hydrochloride is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).Fórmula:C14H26Cl2N6O5Cor e Forma:SolidPeso molecular:428.13417Nattokinase
CAS:Nattokinase is a serine protease derived from nattō, oral， fibrinolytic/anticoagulant properties. It degrades fibrin, fibrinolytic substrates, and PAI-1.Cor e Forma:Yellow SolidUK140
UK140 is an inhibitor of the urokinase-type plasminogen activator (uPA), with Ki values of 0.20 µM for human uPA (huPA) and 2.79 µM for mouse uPA (muPA). UK140 is applicable in studies related to tumor metastasis.Fórmula:C72H105N19O25S3Cor e Forma:SolidPeso molecular:1732.91Bicyclic UK18
CAS:Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.Fórmula:C77H118N26O25S3Cor e Forma:SolidPeso molecular:1904.116-Aminocaproic acid (Standard)
CAS:6-Aminocaproic acid (Standard) is the standard substance of 6-Aminocaproic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 6-Aminocaproic acid (EACA) is an antifibrinolytic agent that acts by inhibiting plasminogen activators which have fibrinolytic properties.Fórmula:C6H13NO2Cor e Forma:SolidPeso molecular:131.17CDE-096
CAS:CDE-096 is a potent inhibitor of plasminogen activator inhibitor-1 that prevents PAI-1–mediated inactivation of tissue plasminogen activator and urokinase plasminogen activator with nanomolar potency, while maintaining activity against glycosylated and multispecies PAI-1, enabling translational research in fibrinolysis and thrombosis regulation.Fórmula:C25H20F3NO12Pureza:99.08%Cor e Forma:Yellow SolidPeso molecular:583.42Ref: TM-T25217
1mg57,00€5mg123,00€1mL*10mM (DMSO)158,00€10mg200,00€25mg423,00€50mg677,00€100mg1.063,00€Tiplaxtinin
CAS:Tiplaxtinin (Tiplasinin)(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 uM.Fórmula:C24H16F3NO4Pureza:99.16% - 99.93%Cor e Forma:SolidPeso molecular:439.38Ref: TM-T2030
2mg42,00€5mg62,00€1mL*10mM (DMSO)69,00€10mg90,00€25mg145,00€50mg245,00€100mg485,00€500mg1.035,00€TM5441
CAS:TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.Cost-effective and quality-assured.Cost-effective and quality-assured.Fórmula:C21H17ClN2O6Pureza:97.62% - 99.09%Cor e Forma:White SolidPeso molecular:428.82UK-371804
CAS:UK-371804: potent uPA blocker; candidate for chronic skin ulcer preclinical studies.Fórmula:C14H16ClN5O4SPureza:95.81% - 99.77%Cor e Forma:SolidPeso molecular:385.83Ref: TM-T3442
1mg49,00€2mg63,00€5mg103,00€1mL*10mM (DMSO)111,00€10mg170,00€25mg306,00€50mg460,00€100mg668,00€500mg1.395,00€Toddalolactone
CAS:Toddalolactone ((+)-Toddalolactone) is an anti-inflammatory and analgesic.Fórmula:C16H20O6Pureza:99.8% - 99.85%Cor e Forma:SolidPeso molecular:308.33Ref: TM-T4S0592
2mg37,00€5mg52,00€1mL*10mM (DMSO)63,00€10mg73,00€25mg105,00€50mg152,00€100mg215,00€200mg320,00€TM5275 sodium
CAS:TM5275 sodium (TM5275 sodium salt) is an inhibitor of plasminogen activator inhibitor 1 (PAI-1).Fórmula:C28H27ClN3NaO5Pureza:98.8% - 99.74%Cor e Forma:SolidPeso molecular:543.98Ref: TM-T4255
2mg39,00€5mg62,00€1mL*10mM (DMSO)67,00€10mg93,00€25mg160,00€50mg231,00€100mg334,00€200mg465,00€Loureirin B
CAS:Loureirin B suppresses fibrosis by modulating MMPs/TIMPs, hindering fibroblast growth, and targeting TGF-β1/Smad2/3 pathway.Fórmula:C18H20O5Pureza:99.33% - 99.86%Cor e Forma:White SolidPeso molecular:316.35TM5007
CAS:TM5007 is a poent inhibitor of plasminogen activator inhibitor-1 (PAI-1; IC50 of 29 uM).Fórmula:C24H20N2O6S4Pureza:96.91%Cor e Forma:SolidPeso molecular:560.69MDI-2268
CAS:MDI-2268, an inhibitor of plasma kallikrein inhibitor 1 (PAI-1), exhibits strong antithrombotic properties. It plays a role in regulating blood coagulation by promoting fibrinolysis and is applicable in research related to deep vein thrombosis.Fórmula:C10H10F3N3O3Cor e Forma:SolidPeso molecular:277.20SK-216
CAS:SK-216,PAI-1 inhibitor. Reduces tumor angiogenesis. Inhibits VEGF-induced endothelial cell migration. Alleviates pulmonary fibrosis.Fórmula:C29H29NNa2O6Pureza:98.29%Cor e Forma:SolidPeso molecular:533.52UK-371804 HCl
CAS:UK-371804 is a potent and selective urokinase-type plasmogen activator (uPA) inhibitor with excellent enzyme potency (Ki=10 nM) and selectivity profile (2700-Fórmula:C14H17Cl2N5O4SPureza:98%Cor e Forma:SolidPeso molecular:422.29Diaplasinin
CAS:Diaplasinin (PAI-749) is a potent inhibitor of plasminogen activator inhibitor-1 (PAI-1) with antithrombotic activity, used in cardiovascular disease research.Fórmula:C32H31N5OPureza:99.02%Cor e Forma:Yellow SolidPeso molecular:501.62Ref: TM-T25915
1mg57,00€5mg120,00€1mL*10mM (DMSO)133,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€p-Aminobenzamidine dihydrochloride
CAS:4-Aminobenzamidine dihydrochloride (p-Aminobenzamidine dihydrochloride) is a strong trypsin inhibitor and a relatively weak inhibitor of urokinase typeFórmula:C7H11Cl2N3Pureza:99.00% - 99.56%Cor e Forma:SolidPeso molecular:208.088Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFórmula:C28H27NO3Pureza:99.21%Cor e Forma:SolidPeso molecular:425.52Ref: TM-T29856
1mg54,00€5mg114,00€1mL*10mM (DMSO)126,00€10mg178,00€25mg409,00€50mg620,00€100mg982,00€200mg1.314,00€AZ3976
CAS:AZ3976 is an inhibitor of PAI-1 with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 displays profibrinolytic activities.Fórmula:C15H19N5O3Pureza:98.14%Cor e Forma:White SolidPeso molecular:317.34ZK824190
CAS:ZK824190: oral uPA inhibitor, IC50 - uPA 237 nM, tPA 1600 nM, Plasmin 1850 nM.Fórmula:C22H20F2N2O4Pureza:98.84%Cor e Forma:White SolidPeso molecular:414.4Ref: TM-T13408
1mg152,00€5mg306,00€1mL*10mM (DMSO)318,00€10mg442,00€25mg675,00€50mg900,00€100mg1.224,00€PPACK
CAS:PPACK: synthetic peptide, irreversibly inhibits thrombin (Ki = 0.24 nM), prevents platelet activation.Fórmula:C21H31ClN6O3Pureza:98%Cor e Forma:SolidPeso molecular:450.96GGACK
CAS:GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).Fórmula:C14H25ClN6O5Cor e Forma:SolidPeso molecular:392.84BT-114143
CAS:BT-114143 is a plasminogen activator inhibitor with an IC50 of 8.42 μM. It is applicable in research related to hemorrhagic diseases caused by excessive fibrinolysis, including traumatic bleeding, severe menorrhagia, postpartum hemorrhage, and complications of hemophilia.Fórmula:C8H11N2O3PCor e Forma:SolidPeso molecular:214.158
