Acetil- CoA Carboxilase
Os inibidores da Acetil-CoA Carboxilase (ACC) são compostos que inibem a atividade da ACC, uma enzima que desempenha um papel crucial na biossíntese de ácidos graxos, convertendo acetil-CoA em malonil-CoA. A inibição da ACC pode reduzir a síntese de lipídios, tornando esses inibidores valiosos na pesquisa de distúrbios metabólicos, obesidade e câncer. Na CymitQuimica, oferecemos uma gama de inibidores da ACC para apoiar sua pesquisa em vias metabólicas, metabolismo de lipídios e desenvolvimento terapêutico.
Foram encontrados 41 produtos para "Acetil- CoA Carboxilase".
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CMS-121
CAS:CMS-121, a quinolone derivative, is an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor.Fórmula:C20H19NO3Pureza:98.71%Cor e Forma:SolidPeso molecular:321.37Fluazifop-P-butyl
CAS:Fluazifop-P-butyl is an arylophenoxypropionate group graminicide that functions as an inhibitor of acetyl-CoA carboxylase (ACCase)[1].Fórmula:C19H20F3NO4Cor e Forma:SolidPeso molecular:383.36MK-4074
CAS:MK-4074 is a liver-specific acetyl-CoA carboxylase ACC1 and ACC2 inhibitor(IC50 of 3 nM).Fórmula:C33H31N3O6Cor e Forma:SolidPeso molecular:565.62Sethoxydim
CAS:Sethoxydim is an effective herbicide.Fórmula:C17H29NO3SCor e Forma:SolidPeso molecular:327.48Spiromesifen
CAS:Spiromesifen is a useful miticide and insecticide in plant breeding. It is particuarly useful against spider mites and whiteflies in vitro.Fórmula:C23H30O4Pureza:98%Cor e Forma:SolidPeso molecular:370.48Cycloxydim
CAS:Cycloxydim is a cyclohexene oxime herbicide that is used for the control of grass weeds of many agricultural and horticultural broad-leaved crops.Fórmula:C17H27NO3SCor e Forma:SolidPeso molecular:325.47(Rac)-Spirotetramat-enol
CAS:(Rac)-Spirotetramat-enol (Compound 8) serves as a ligand for target proteins, utilized in the synthesis of PROTAC ACC degrader.Fórmula:C18H23NO3Cor e Forma:SolidPeso molecular:301.38CP-610431
CAS:CP-610431 inhibits ACC1/ACC2 (nonselective) with ~50 nM IC50, potentially aiding metabolic syndrome research.Fórmula:C30H37N3O2Cor e Forma:SolidPeso molecular:471.645Lipid Metabolism Compound Library
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
Cor e Forma:Odour SolidPROTAC ACC degrader-1
PROTAC ACC degrader-1 (Compound 9b), an Acetyl-CoA Carboxylase degrader, demonstrates remarkable effectiveness, with a potent activity characterized by an IC 50 of 107.8 μg/mL against Aphis craccivora.Fórmula:C37H42N4O8Cor e Forma:SolidPeso molecular:670.75Clodinafop-propargyl
CAS:Clodinafop-propargyl is used to control grass weeds in cereals postemergence, targeting species like Avena and Lolium.Fórmula:C17H13ClFNO4Pureza:98.85%Cor e Forma:SolidPeso molecular:349.74Cyhalofop-butyl
CAS:Cyhalofop-butyl is an ACCase (acetyl-coenzyme A carboxylase) inhibitor and herbicide that suppresses plant lipid synthesis at the meristematic level.Fórmula:C20H20FNO4Pureza:99.83%Cor e Forma:White SolidPeso molecular:357.38Quizalofop-p-ethyl
CAS:Quizalofop-p-ethyl ((R)-Quizalofop ethyl) is a selective post-emergent herbicide for annual and perennial weeds, acetyl-CoA carboxylase (ACCase) inhibitor.Fórmula:C19H17ClN2O4Pureza:97.87%Cor e Forma:SolidPeso molecular:372.80Firsocostat
CAS:Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM).Fórmula:C28H31N3O8SPureza:98% - 99.39%Cor e Forma:White SolidPeso molecular:569.63Ref: TM-T7184
1mg92,00€2mg120,00€5mg200,00€1mL*10mM (DMSO)251,00€10mg334,00€25mg484,00€50mg622,00€100mg859,00€500mg1.701,00€Olumacostat Glasaretil
CAS:Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC). It has been used in trials studying the treatment of Acne Vulgaris.Fórmula:C26H43NO7Pureza:97.79% - 99.34%Cor e Forma:SolidPeso molecular:481.62ND-646
CAS:ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2,Fórmula:C28H32N4O7SPureza:98.64%Cor e Forma:White SolidPeso molecular:568.64Ref: TM-TQ0243
1mg62,00€5mg177,00€1mL*10mM (DMSO)222,00€10mg289,00€25mg492,00€50mg708,00€100mg954,00€200mg1.288,00€Haloxyfop
CAS:(±)-Haloxyfop (Haloxyfop Acid) is a herbicide.Fórmula:C15H11ClF3NO4Pureza:99.96% - >99.99%Cor e Forma:SolidPeso molecular:361.7CP-640186
CAS:CP-640186 is an isozyme-nonselective ACCase inhibitor. The IC50s of CP-640186 is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.Fórmula:C30H35N3O3Pureza:99.87%Cor e Forma:White SolidPeso molecular:485.62TOFA
CAS:TOFA (MDL14514) is an allosteric inhibitor of acetyl-CoA carboxylase-α (ACCA).Fórmula:C19H32O4Pureza:97.52% - 98.98%Cor e Forma:Yellow SolidPeso molecular:324.45VY-3-135
CAS:VY-3-135 is an orally active, stable and specific acetyl-CoA synthetase 2 (ACSS2) inhibitor.Cost-effective and quality-assured.Fórmula:C26H27N3O3Pureza:98.74% - 99.79%Cor e Forma:White SolidPeso molecular:429.51CP-640186 hydrochloride
CAS:CP-640186 hydrochloride (CP 640186 HCl) is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor, including rat liver ACC1 (IC50: 53 nM) and ratFórmula:C30H36ClN3O3Pureza:98.86%Cor e Forma:SolidPeso molecular:522.08PF-05221304
CAS:PF-05221304 (NSC-170984) is an orally active, liver-targeted inhibitor of acetyl-CoA carboxylase (ACC), a rate-limiting enzymes for fatty acid synthesis.Fórmula:C28H30N4O5Pureza:98.82% - 99.50%Cor e Forma:SolidPeso molecular:502.56Ref: TM-T9209
1mg89,00€5mg164,00€10mg239,00€1mL*10mM (DMSO)241,00€25mg414,00€50mg538,00€100mg783,00€200mg1.054,00€ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His)
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.Cor e Forma:Lyophilized PowderPeso molecular:69.9 kDa (predicted)Ref: TM-TMPH-03432
5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€1mg2.277,00€ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His)
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.Cor e Forma:Lyophilized PowderPeso molecular:67.6 kDa (predicted)Ref: TM-TMPH-03431
5µg120,00€10µg195,00€20µg324,00€50µg489,00€100µg670,00€200µg964,00€500µg1.558,00€1mg2.277,00€Quizalofop-ethyl
CAS:Quizalofop-ethyl is a post-emergence herbicide for grass weeds in broadleaf crops. It works by inhibiting the ACCase enzyme.Fórmula:C19H17ClN2O4Pureza:98.82%Cor e Forma:SolidPeso molecular:372.8PF-05175157
CAS:PF 05175157 is an inhibitor of acetyl-CoA carboxylase 1 (ACC1) and ACC2 (IC50s = 27, 33, 23.5, and 50.4 nM for human ACC1, human ACC2, rat ACC1, and rat ACC2,Fórmula:C23H27N5O2Pureza:98% - 99.92%Cor e Forma:White SolidPeso molecular:405.49Ref: TM-T7163
1mg34,00€2mg44,00€5mg63,00€1mL*10mM (DMSO)70,00€10mg90,00€25mg173,00€50mg295,00€100mg477,00€200mg677,00€Tralkoxydim
CAS:Produto ControladoTralkoxydim (Tralkoxydime) is an alkyl ketone herbicide. Tralkoxydim works as an ACCase inhibitor.Fórmula:C20H27NO3Pureza:97.44%Cor e Forma:White SolidPeso molecular:329.43ACC1/2-IN-2
CAS:PF-3: potent ACC1/2 inhibitor; IC50: 22 nM (ACC1), 48 nM (ACC2); anti-cancer research potential.Fórmula:C24H25N3O3Cor e Forma:SolidPeso molecular:403.47Propaquizafop
CAS:Propaquizafop, a phenoxyisopropionic acid derivative, is used as a herbicide.Fórmula:C22H22ClN3O5Pureza:98%Cor e Forma:SolidPeso molecular:443.88Acetyl-CoA Carboxylase-IN-1
CAS:Acetyl-CoA Carboxylase-IN-1 (ACC-IN-1) is a potent acetyl-CoA carboxylase (ACC) inhibitor with antibacterial activity, used in metabolic disease research.Fórmula:C13H9Br2N5Pureza:98.73%Cor e Forma:SolidPeso molecular:395.05Clethodim
CAS:Clethodim is a selective herbicide inhibiting acetyl-CoA carboxylase, effective on grasses with low environmental persistence and moderate toxicity to wildlife.Fórmula:C17H26ClNO3SPureza:99.99%Cor e Forma:Brown OilPeso molecular:359.91hACC2-IN-1
CAS:hACC2-IN-1 is a potent inhibitor of acetyl coenzyme A carboxylase 2 (ACC2) with an IC50 value of 2.5 μM for hACC2. hACC2-IN-1 has potential for obesity studies.Fórmula:C23H32N2O4SCor e Forma:SolidPeso molecular:432.58A-908292
CAS:A-908292: potent ACC2 inhibitor with 38 nM IC50, useful for studying fatty acid metabolism.Fórmula:C18H20N2O4SCor e Forma:SolidPeso molecular:360.43ACC1/2-IN-1
CAS:ACC1/2-IN-1 is a potent inhibitor of ACC1/2 and acts on ACC1 (IC50: 98.06 nM) and ACC2 (IC50: 29.43 nM). ACC1/2-IN-1 can be used in cancer research.Fórmula:C34H32N4O4Cor e Forma:SolidPeso molecular:560.64S-2E
CAS:S-2E, an oral inhibitor of HMG-CoA reductase/acetyl-CoA carboxylase, treats hyperlipidemia.Fórmula:C22H25NO4Cor e Forma:SolidPeso molecular:367.44Quizalofop
CAS:Quizalofop (Xylafop) is a reagent of biochemical.Fórmula:C17H13ClN2O4Pureza:97.14%Cor e Forma:White SolidPeso molecular:344.75Ref: TM-T19959
5mg52,00€1mL*10mM (DMSO)65,00€10mg73,00€25mg105,00€50mg156,00€100mg224,00€500mg557,00€Quizalofop-P
CAS:Quizalofop-P, a selective herbicide, is absorbed by weed stems and leaves before translocating both upward and downward within the plant, concentrating inFórmula:C17H13ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:344.75AD-5584
CAS:AD-5584, an ACSS2 inhibitor with blood-brain permeability, significantly reduces lipid storage and colony formation while increasing cell death, demonstrating antitumor activity [1].Fórmula:C22H24ClFN4OCor e Forma:SolidPeso molecular:414.9AMPK activator 16
CAS:AMPK activator16 (compound 6) functions as an AMP-activated protein kinase (AMPK) inhibitor. It interacts effectively with crucial AMPK residues, significantly activating the enzyme. In N2a cells, AMPK activator16 enhances the expression of phosphorylated AMPK (p-AMPK) and its downstream signaling proteins, such as phosphorylated ACC (Acetyl-CoA Carboxylase) and phosphorylated raptor (p-raptor).Fórmula:C23H20ClNO5SCor e Forma:SolidPeso molecular:457.927THR-β agonist 9
CAS:THR-β agonist 9 is a potent and selective THR-β activator, which shows sensitivity to His435 mutations with an EC50 of 3.2 nM. It demonstrates moderate selectivity, approximately 10-fold, and effectively activates various His435 mutants (H435A, H435Y, and H435R), with EC50 values ranging from 134.2 nM to 515.5 nM. THR-β agonist 9 presents potential for research into conditions such as dyslipidemia, metabolic syndrome-associated steatohepatitis (MASH), and resistance to thyroid hormone (RTH).Fórmula:C23H18N2O6Peso molecular:418.40Moiramide B
CAS:Moiramide B is an acetyl coenzyme A carboxylase inhibitor with antimicrobial activity, strongly inhibiting Gram-positive bacteria.Fórmula:C25H31N3O5Pureza:98.53% - 99.74%Cor e Forma:SolidPeso molecular:453.53
