Cisteína Protease
Os inibidores de protease de cisteína são compostos que visam e inibem as proteases de cisteína, uma classe de enzimas que degradam proteínas ao clivar ligações peptídicas nas quais um resíduo de cisteína atua como nucleófilo. Essas enzimas estão envolvidas em vários processos fisiológicos, incluindo apoptose, resposta imune e renovação proteica. Os inibidores de protease de cisteína são cruciais para o estudo de doenças como câncer, distúrbios neurodegenerativos e infecções parasitárias. Na CymitQuimica, oferecemos inibidores de protease de cisteína para apoiar sua pesquisa em proteólise, regulação celular e descoberta de medicamentos.
Foram encontrados 96 produtos de "Cisteína Protease"
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VK13
<p>VK13 (Compound 6) is a potent inhibitor of human cathepsin L (hCatL) and SARS-CoV-2 3CLpro (3CL-PR), with Ki values of 2.6 nM and 0.55 nM, respectively. It also exhibits activity against CoV-2, with an EC50 value of 1.25 μM.</p>Fórmula:C24H28N4O5Cor e Forma:SolidPeso molecular:452.503Mpro/Cathepsin L-IN-1
Mpro/Cathepsin L-IN-1 (Compound 4d) is an inhibitor of SARS-CoV-2 Mpro and hCatL, with Ki values of 5.54 μM and 0.701 μM, respectively.Fórmula:C24H32FN3O4Peso molecular:445.23768Z-FG-NHO-Bz
CAS:<p>Z-FG-NHO-Bz is a selective inhibitor of cathepsin [1].</p>Fórmula:C26H25N3O6Cor e Forma:SolidPeso molecular:475.49Z-Phe-Tyr(tBu)-diazomethylketone
CAS:<p>Irreversible cathepsin L inhibitor which is ca 10'000 times more effective in inactivating cathepsin L than cathepsin S.</p>Fórmula:C31H34N4O5Cor e Forma:SolidPeso molecular:542.636Z-L(D-Val)G-CHN2
<p>Z-L(D-Val)G-CHN2, an isoform of Z-LVG-CHN2, serves as a cell-permeable and irreversible inhibitor of cysteine proteinase.</p>Fórmula:C22H31N5O5Pureza:98%Cor e Forma:SolidPeso molecular:445.51Relacatib
CAS:<p>Relacatib (SB-462795) is a potent cathepsins K, L, V inhibitor with high affinity (Ki: 41-68 pM) and reduces bone resorption effectively.</p>Fórmula:C27H32N4O6SCor e Forma:SolidPeso molecular:540.64LN5P45
<p>LN5P45, an OTUB2 inhibitor (IC50: 2.3 μM), promotes monoubiquitination of OTUB2 at lysine 31 and is utilized in the study of tumor progression and metastasis [1</p>Fórmula:C13H15ClN2O2Cor e Forma:SolidPeso molecular:266.72Odanacatib
CAS:<p>Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.</p>Fórmula:C25H27F4N3O3SPureza:98.53% - 99.53%Cor e Forma:SolidPeso molecular:525.56JTE-607
CAS:<p>JTE-607 is a cytokine production inhibitor. JTE-607 induces apoptosis accompanied by an increase in p21waf1/cip1 in acute myelogenous leukemia cells.</p>Fórmula:C25H33Cl4N3O5Pureza:97.88%Cor e Forma:SolidPeso molecular:597.36E-64
CAS:<p>E-64 (Proteinase inhibitor E 64) is an irreversible and specific cysteine protease inhibitor. The IC50 of E-64 for papain is 9 nM.</p>Fórmula:C15H27N5O5Pureza:98% - 99.95%Cor e Forma:White SolidPeso molecular:357.41KGP94
CAS:<p>KGP94 is a potent, selective, and competitive inhibitor of the lysosomal endopeptidase enzyme.</p>Fórmula:C14H12BrN3OSPureza:99.6%Cor e Forma:SolidPeso molecular:350.23Balicatib
CAS:<p>Balicatib (AAE581) is a potent and selective inhibitor of cathepsin K, used in trials studying the treatment of osteoporosis.</p>Fórmula:C23H33N5O2Pureza:97.78% - 98.17%Cor e Forma:White To Off-White Solid PowderPeso molecular:411.542-Cyanopyrimidine
CAS:<p>2-Cyanopyrimidine (m-Hydroxyphenylpropionic acid) is inhibitor of cathepsin K(IC50 : 170 nM)</p>Fórmula:C5H3N3Pureza:99.27%Cor e Forma:Crystalline SolidPeso molecular:105.1L-006235
CAS:L-006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.Fórmula:C24H30N6O2SPureza:99.37%Cor e Forma:SolidPeso molecular:466.6MDL-28170
CAS:<p>MDL-28170 (Calpain Inhibitor III) is a Cysteine protease.</p>Fórmula:C22H26N2O4Pureza:95.06%Cor e Forma:SolidPeso molecular:382.45CA-074 methyl ester
CAS:<p>CA-074 methyl ester (Cathepsin B Inhibitor IV) is a selective inhibitor of Cathepsin B (IC50=36.3 nM). neuroprotective effect. High-Quality, Low-Cost!</p>Fórmula:C19H31N3O6Pureza:97.26% - 99.58%Cor e Forma:SolidPeso molecular:397.47LY 3000328
CAS:<p>LY 3000328 (Cathepsin S inhibitor) is a selective inhibitor of cathepsin S.Cost-effective and quality-assured.</p>Fórmula:C25H29FN4O5Pureza:97.83% - 99.54%Cor e Forma:SolidPeso molecular:484.52(1S,2R)-Alicapistat
CAS:<p>(1S,2R)-Alicapistat inhibits calpains 1 and 2, shows promise for Alzheimer's, and has an IC50 of 395 nM.</p>Fórmula:C25H27N3O4Pureza:99.60%Cor e Forma:SoildPeso molecular:433.5Cathepsin Inhibitor 1
CAS:<p>Cathepsin Inhibitor 1 is an inhibitor of Cathepsin (L, L2, S, K, B) with pIC50 of 7.9, 6.7, 6.0, 5.5 and 5.2, respectively.</p>Fórmula:C20H24ClN5O2Pureza:99.78%Cor e Forma:SolidPeso molecular:401.89GSK2793660 HCl
CAS:<p>GSK2793660 is a irreversible covalent α,β-unsaturated amide based DPP1 inhibitor.</p>Fórmula:C22H32ClN3O3Cor e Forma:SolidPeso molecular:421.96
