DPP-4
Os inibidores de DPP-4 são compostos que inibem a Dipeptidil Peptidase-4, uma enzima envolvida na inativação de hormonas incretinas, que regulam o metabolismo da glicose. Ao inibir a DPP-4, estes compostos ajudam a prolongar a ação das hormonas incretinas, aumentando a secreção de insulina e reduzindo os níveis de glicose no sangue. Os inibidores de DPP-4 são amplamente utilizados no tratamento do diabetes tipo 2 e em pesquisas focadas em distúrbios metabólicos. Na CymitQuimica, oferecemos inibidores de DPP-4 para apoiar sua pesquisa em endocrinologia, manejo do diabetes e doenças metabólicas.
Foram encontrados 94 produtos para "DPP-4".
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AMG-222
CAS:AMG-222 (ALS-2-0426, ALS-20426) is a DPP-4 inhibitor and may be used in the treatment of type 2 diabetes.Fórmula:C32H39N9O3Cor e Forma:SolidPeso molecular:597.71Sulphostin
Sulphostin is a covalent inhibitor of dipeptidyl peptidase 4 (DPP4), dipeptidyl peptidase 9 (DPP9), and dipeptidyl peptidase 8 (DPP8), with IC50 values of 79, 1392, and 6930 nM, respectively. It induces phosphorylation of amino sulfamide esters, irreversibly inhibiting enzyme activity. Sulphostin is applicable in inflammation and cancer research.Talabostat isomer mesylate
Talabostat isomer mesylate, a PT100/Val-boroPro variant, is a potent oral DPP-IV inhibitor (Ki: 0.18 nM).Fórmula:C10H23BN2O6SPureza:98%Cor e Forma:SolidPeso molecular:310.18SGLT2-IN-5
SGLT2-IN-5 (Compound 99) is an orally active SGLT2 inhibitor with IC₅₀ values of 0.8 nM for SGLT2, 23 nM for SGLT1, and 58 nM for DPP4. In diabetic rat models, SGLT2-IN-5 effectively regulates blood glucose and increases the levels of active GLP-1. It is suitable for research on type 2 diabetes.MPO-IN-7
MPO-IN-7 (compound MDC) is a myeloperoxidase inhibitor with IC50 values of 41 μM for α-glucosidase, 25 μM for dipeptidyl peptidase-4, and 4.5 μM for myeloperoxidase. MPO-IN-7 exhibits antioxidant and anti-inflammatory activities in vitro.Fórmula:C16H14N2O6Cor e Forma:SolidPeso molecular:330.08519Ellipyrone B
Ellipyrone B, a γ-pyrone-based macrocyclic polyketide with antihyperglycemic properties, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50Fórmula:C25H38O7Cor e Forma:SolidPeso molecular:450.57Talabostat
CAS:Talabostat (PT100, Val-boroPro) is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM.Fórmula:C9H19BN2O3Cor e Forma:SolidPeso molecular:214.07Sitagliptin fenilalanil hydrochloride
CAS:Sitagliptin fenilalanil hydrochloride is an orally active DPP-4 inhibitor. Sitagliptin fenilalanil hydrochloride is used in diabetes research.Fórmula:C25H25ClF6N6O2Pureza:98.32%Cor e Forma:White SolidPeso molecular:590.95Dutogliptin
CAS:Dutogliptin (PHX-1149 free base) is an oral, effective and selective dipeptide-peptide-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus.Fórmula:C10H20BN3O3Pureza:98%Cor e Forma:SolidPeso molecular:241.095VAMP
VAMP is a tetrapeptide that acts as a competitive dipeptidyl peptidase IV (DPP-IV) inhibitor, exhibiting an IC50 of 1.00 μM and a Kd of 6.89 μM. It effectively targets the DPP-IV-GLP-1 axis and is utilized in the research of type 2 diabetes.Fórmula:C18H32N4O5SCor e Forma:SolidPeso molecular:416.535HAEGT
CAS:HAEGT is the first N-terminal 1-5 residues of GLP-1 peptide.Fórmula:C20H31N7O9Pureza:98%Cor e Forma:SolidPeso molecular:513.5016Sitagliptin fenilalanil
CAS:Sitagliptin fenilalanil is a DPP-4 (dipeptidyl peptidase-4) inhibitor that inhibits DPP-4 enzyme activity.Fórmula:C25H24F6N6O2Pureza:98.82%Cor e Forma:SolidPeso molecular:554.49DPP4/CD26 Protein, Mouse, Recombinant (His)
DPP4/CD26 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:85.69 kDa (predicted); 100-120 kDa (due to glycosylation)DPP4/CD26 Protein, Mouse, Recombinant (hFc)
DPP4/CD26 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Pureza:99% - > 95 % as determined by SDS-PAGE.Cor e Forma:White Lyophilized PowderPeso molecular:112.9 kDa (predicted)Alogliptin-13CD3
CAS:Alogliptin (SYR-322) 13CD3 is the deuterium-labeled Alogliptin. Alogliptin is a selective inhibitor of DPP-4.Fórmula:C18H21N5O2Pureza:98%Cor e Forma:SolidPeso molecular:343.4Retagliptin
CAS:Retagliptin is a DPP-4 inhibitor potentially used to treat Type 2 diabetes.Fórmula:C19H18F6N4O3Cor e Forma:SolidPeso molecular:464.36Nateglinide-D5
CAS:Nateglinide D5 is a deuterium labeled Nateglinide.Fórmula:C19H27NO3Pureza:98%Cor e Forma:SolidPeso molecular:322.4534Teneligliptin-D8
CAS:Teneligliptin D8 a deuterium labeled Teneligliptin (MP-513). Teneligliptin is a potent, orally available, competitive, and long-lasting inhibitor of DPP-4.Fórmula:C22H30N6OSPureza:98%Cor e Forma:SolidPeso molecular:434.63Diprotin A TFA
CAS:Diprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV).Fórmula:C19H32F3N3O6Cor e Forma:SolidPeso molecular:455.4691Saxagliptin hydrochloride
CAS:Saxagliptin: oral DPP-4 inhibitor, enhances incretins, manages type 2 diabetes by reducing glucose levels.Fórmula:C18H26ClN3O2Cor e Forma:SolidPeso molecular:351.871
