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Wnt/beta-catenina

Wnt/beta-catenina

Os inibidores de Wnt/beta-catenina são compostos que visam e inibem a via de sinalização Wnt/beta-catenina, crucial para a regulação do desenvolvimento embrionário, proliferação celular e manutenção das células-tronco. A desregulação desta via está ligada a vários tipos de câncer e doenças degenerativas. Os inibidores da sinalização Wnt/beta-catenina são valiosos em pesquisas focadas em entender o papel dessa via na doença e no desenvolvimento de terapias direcionadas. Na CymitQuimica, oferecemos inibidores de Wnt/beta-catenina para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e pesquisa oncológica.

Foram encontrados 66 produtos de "Wnt/beta-catenina"

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  • MSAB
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    MSAB

    CAS:
    <p>MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.</p>
    Fórmula:C15H15NO4S
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:305.35

    Ref: TM-T8710

  • IWP-4
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    IWP-4

    CAS:
    <p>IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.</p>
    Fórmula:C23H20N4O3S3
    Pureza:98% - 99.59%
    Cor e Forma:Solid
    Peso molecular:496.62

    Ref: TM-T4245

  • PRI-724
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    PRI-724

    CAS:
    <p>PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.</p>
    Fórmula:C33H35N6O7P
    Pureza:98.25% - 99.11%
    Cor e Forma:Soild
    Peso molecular:658.64

    Ref: TM-T64414

  • Wnt pathway activator 2
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    Wnt pathway activator 2

    CAS:
    <p>Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.</p>
    Fórmula:C17H15NO4
    Pureza:99.41%
    Cor e Forma:Solid
    Peso molecular:297.31

    Ref: TM-T13345

  • ZW4864 free base
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    ZW4864 free base

    CAS:
    <p>ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.</p>
    Fórmula:C33H42N6O3
    Pureza:99.81%
    Cor e Forma:Solid
    Peso molecular:570.72

    Ref: TM-T9642

  • β-catenin/CBP-IN-1
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    β-catenin/CBP-IN-1

    CAS:
    <p>β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-catenin</p>
    Fórmula:C33H35N6O7P
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:658.64

    Ref: TM-T12537

  • GB1874
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    GB1874

    CAS:
    <p>GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.</p>
    Fórmula:C24H27N3O2S
    Cor e Forma:Solid
    Peso molecular:421.56

    Ref: TM-T71624

  • Wnt/β-catenin agonist 4
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    Wnt/β-catenin agonist 4

    CAS:
    <p>Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.</p>
    Fórmula:C16H15FN4O2
    Pureza:99.61%
    Cor e Forma:Solid
    Peso molecular:314.31

    Ref: TM-T60803

  • FzM1
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    FzM1

    CAS:
    <p>FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)</p>
    Fórmula:C21H16N2O2S
    Pureza:99.37% - 99.89%
    Cor e Forma:Solid
    Peso molecular:360.43

    Ref: TM-T24076

  • FzM1.8
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    FzM1.8

    CAS:
    <p>FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.</p>
    Fórmula:C18H14N2O4
    Pureza:99.89%
    Cor e Forma:Solid
    Peso molecular:322.31

    Ref: TM-T15363

  • Miclxin
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    Miclxin

    CAS:
    <p>Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potent</p>
    Fórmula:C26H27N5O2
    Pureza:99.17% - 99.99%
    Cor e Forma:Solid
    Peso molecular:441.52

    Ref: TM-T73415

  • JW 67
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    JW 67

    CAS:
    <p>JW 67 is an inhibitor of canonical Wnt pathway signaling.</p>
    Fórmula:C21H18N2O6
    Pureza:99.02%
    Cor e Forma:Solid
    Peso molecular:394.38

    Ref: TM-T22884

  • CDK8-IN-11
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    CDK8-IN-11

    CAS:
    <p>CDK8-IN-11 is a CDK8 inhibitor that demonstrates anti-proliferative activity against colon cancer cell lines and inhibits the activation of WNT/β-catenin.</p>
    Fórmula:C19H15F3N4O2
    Pureza:99.74%
    Cor e Forma:Solid
    Peso molecular:388.34

    Ref: TM-T61742

  • Carboxylesterase-IN-3
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    Carboxylesterase-IN-3

    CAS:
    <p>Carboxylesterase-IN-3 is a potent inhibitor of Carboxylesterase Notum (IC50 ≤ 10 nM).Carboxylesterase-IN-3 has the potential to study cancer diseases.</p>
    Fórmula:C11H6Cl2N4OS
    Pureza:97.49% - 98.47%
    Cor e Forma:Solid
    Peso molecular:313.16

    Ref: TM-T60788

  • β-Catenin modulator-8
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    β-Catenin modulator-8

    CAS:
    <p>β-Catenin modulator-8 (Compound Ⅸa) is a specific β-catenin modulator for use in cancer research.</p>
    Fórmula:C17H20N2O2S
    Pureza:99.97%
    Cor e Forma:Solid
    Peso molecular:316.42

    Ref: TM-T205083

  • NRX-103095
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    NRX-103095

    CAS:
    <p>NRX-103095 increases β-catenin binding to SCFβ-TrCP E3 ligase; EC50 is 163 nM for pSer33/Ser37 affinity boost.</p>
    Fórmula:C22H16Cl2F3N3O3S
    Pureza:99.58% - 99.95%
    Cor e Forma:Solid
    Peso molecular:530.35

    Ref: TM-T63730