Wnt/beta-catenina
Os inibidores de Wnt/beta-catenina são compostos que visam e inibem a via de sinalização Wnt/beta-catenina, crucial para a regulação do desenvolvimento embrionário, proliferação celular e manutenção das células-tronco. A desregulação desta via está ligada a vários tipos de câncer e doenças degenerativas. Os inibidores da sinalização Wnt/beta-catenina são valiosos em pesquisas focadas em entender o papel dessa via na doença e no desenvolvimento de terapias direcionadas. Na CymitQuimica, oferecemos inibidores de Wnt/beta-catenina para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e pesquisa oncológica.
Foram encontrados 69 produtos para "Wnt/beta-catenina".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Wnt pathway activator 1
CAS:Wnt pathway activator 1 is a potent Wnt activator with an IC50 of 28-29 nM.Fórmula:C18H16O4Pureza:99.93%Cor e Forma:SolidPeso molecular:296.32Ref: TM-T17256
2mg33,00€5mg49,00€1mL*10mM (DMSO)50,00€10mg75,00€25mg124,00€50mg200,00€100mg299,00€200mg430,00€WAY 316606
CAS:WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt.Fórmula:C18H19F3N2O4S2Pureza:99.65%Cor e Forma:SolidPeso molecular:448.48Tegatrabetan
CAS:Tegatrabetan (BC2059) is a small molecule inhibitor of the Wnt/beta-catenin pathway with potential antineoplastic activity.Fórmula:C28H36N4O6S2Pureza:98.47% - 99.95%Cor e Forma:SolidPeso molecular:588.74Ref: TM-T5642
1mg38,00€2mg50,00€5mg80,00€1mL*10mM (DMSO)92,00€10mg117,00€25mg198,00€50mg316,00€100mg535,00€Fz7-21
CAS:Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.Fórmula:C83H114N18O23S2Pureza:99.8%Cor e Forma:White SolidPeso molecular:1796.03KYA1797K
CAS:KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.Fórmula:C17H11N2O6S2·KPureza:97.57% - 99.33%Cor e Forma:SolidPeso molecular:442.51Ref: TM-T6868
2mg39,00€5mg56,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg178,00€50mg301,00€100mg485,00€200mg690,00€Pyrvinium pamoate
CAS:Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drugFórmula:C26H28N3C23H14O6Pureza:99.76% - >99.99%Cor e Forma:Red SolidPeso molecular:575.71BML-284 hydrochloride
CAS:BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.Fórmula:C19H19ClN4O3Pureza:99.80%Cor e Forma:SolidPeso molecular:386.84Ref: TM-T8820
1mg34,00€5mg64,00€10mg84,00€1mL*10mM (DMSO)94,00€25mg142,00€50mg253,00€100mg439,00€200mg615,00€500mg964,00€WAY-262611
CAS:WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.Fórmula:C20H22N4Pureza:98.09% - 99.09%Cor e Forma:SolidPeso molecular:318.42MSAB
CAS:MSAB inhibits Wnt/β-catenin by binding to β-catenin and inducing its breakdown.Fórmula:C15H15NO4SPureza:99.76%Cor e Forma:SolidPeso molecular:305.35Ref: TM-T8710
1mg34,00€2mg47,00€5mg70,00€1mL*10mM (DMSO)78,00€10mg113,00€25mg222,00€50mg334,00€100mg507,00€500mg1.063,00€IWP-4
CAS:IWP-4 (Inhibitor of Wnt Production-4) is a potent Wnt inhibitor.Fórmula:C23H20N4O3S3Pureza:98% - 99.59%Cor e Forma:Yellow SolidPeso molecular:496.62PRI-724
CAS:PRI-724 is a second-generation, selective small molecule inhibitor of the β-catenin/CBP interaction.Cost-effective and quality-assured.Fórmula:C33H35N6O7PPureza:98.25% - 98.38%Cor e Forma:White SolidPeso molecular:658.64Setrusumab
CAS:Setrusumab (BPS 804) is a sclerostin-targeting antibody used in bone remodeling and Wnt signaling research.Pureza:95% - >95% (SDS-PAGE); 97.8% (SEC-HPLC)Cor e Forma:LiquidTNKS-IN-1
CAS:TNKS-IN-1 is a tankyrase inhibitor used in Wnt/β-catenin signaling and colorectal cancer research models.Fórmula:C18H18N2OPureza:99.98%Cor e Forma:SolidPeso molecular:278.35GB1874
CAS:GB1874 is an inhibitor of the Wnt pathway targeting β-catenin-TCF4 protein-protein interaction (PPI), affecting proliferation in Wnt-dependent CRC cells.Fórmula:C24H27N3O2SCor e Forma:Yellow SolidPeso molecular:421.56Wnt pathway activator 2
CAS:Wnt pathway activator 2 is a potent Wnt activator with an IC50 of 13 nM.Fórmula:C17H15NO4Pureza:99.41%Cor e Forma:White SolidPeso molecular:297.31TNIK-IN-1
CAS:TNIK-IN-1 is a potent TNIK inhibitor (IC50 = 65 nM). It exerts antitumor effects by disrupting the Wnt signaling pathway, utilized in research for colorectal cancer and cancer stemness mechanisms.Fórmula:C19H17N5O3SPureza:99.01%Cor e Forma:SolidPeso molecular:395.43FJ9
CAS:FJ9 is an FZD7 inhibitor that disrupts the protein interaction between Frz7 and the DVL PDZ domain and induces apoptosis in melanoma and non-small cell lung cancer cell lines.Fórmula:C23H27NO3Pureza:99.41% - 99.60%Cor e Forma:White SolidPeso molecular:365.47ZW4864 free base
CAS:ZW4864 (free base) is an orally active and selective β catenin/B-Cell lymphoma 9 protein protein interaction ( β catenin/BCL9 PPI ) inhibitor.Fórmula:C33H42N6O3Pureza:99.81%Cor e Forma:SolidPeso molecular:570.72Ref: TM-T9642
1mg152,00€5mg371,00€1mL*10mM (DMSO)409,00€10mg557,00€25mg887,00€50mg1.198,00€100mg1.611,00€500mg3.232,00€β-catenin/CBP-IN-1
CAS:β-catenin/CBP-IN-1 is a potent and selective inhibitor of CBP/β-cateninFórmula:C33H35N6O7PPureza:98%Cor e Forma:SolidPeso molecular:658.64FzM1
CAS:FzM1, a negative allosteric modulator (NAM) of the Frizzled receptor FZD4, diminishes WNT5A-dependent WNT responsive element (WRE) activity (log EC50inh=−6.2)Fórmula:C21H16N2O2SPureza:99.37% - 99.89%Cor e Forma:Yellow SolidPeso molecular:360.43Ref: TM-T24076
1mg39,00€1mL*10mM (DMSO)58,00€5mg60,00€10mg94,00€25mg178,00€50mg310,00€100mg500,00€500mg1.071,00€
