Células - tronco
Os inibidores de células-tronco são compostos que atuam especificamente nas células-tronco e em suas vias de sinalização, afetando sua capacidade de autorrenovação e diferenciação. Esses inibidores são cruciais em pesquisas focadas no controle do comportamento das células-tronco, na compreensão dos processos de desenvolvimento e no desenvolvimento de terapias para doenças como o câncer, onde se acredita que as células-tronco desempenhem um papel fundamental. Na CymitQuimica, oferecemos uma variedade de inibidores de células-tronco para apoiar sua pesquisa em medicina regenerativa, biologia do desenvolvimento e oncologia.
Foram encontrados 486 produtos de "Células - tronco"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BRD0705
CAS:<p>BRD0705: potent, selective GSK3α inhibitor, oral, IC50: 66 nM, 8x more selective than GSK3β.</p>Fórmula:C20H23N3OPureza:99.01%Cor e Forma:SolidPeso molecular:321.42NGP555
CAS:<p>NGP555 is a modulator of γ-secretase.</p>Fórmula:C23H23FN4SPureza:99.86%Cor e Forma:SolidPeso molecular:406.52Netarsudil Dihydrochloride
CAS:<p>Netarsudil Dihydrochloride (AR-13324 Dihydrochloride) is an inhibitor of Rho-related protein kinase (ROCK) and norepinephrine transporter (NET) and is effective in reducing intraocular pressure (IOP).Cost-effective and quality-assured.</p>Fórmula:C28H29Cl2N3O3Pureza:99.94% - 99.98%Cor e Forma:SolidPeso molecular:526.45Brepocitinib P-Tosylate
CAS:<p>Brepocitinib P-Tosylate (PF-06700841 P-Tosylate) is a potent dual inhibitor of Janus kinase 1 (JAK1) and TYK2 (IC50s of 17 nM and 23 nM, respectively).</p>Fórmula:C25H29F2N7O4SPureza:99.82% - 99.97%Cor e Forma:SolidPeso molecular:561.6Ponsegromab
CAS:<p>Ponsegromab (PF 06946860), a humanized anti-GDF15 antibody, may treat cancer cachexia by blocking GDF15/GFRAL signaling.</p>Pureza:100% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:146.08 kDaSonidegib diphosphate
CAS:<p>Sonidegib diphosphate (LDE225 diphosphate) is a selective antagonist of Smo that inhibits murine Smo and human Smo.Cost-effective and quality-assured.</p>Fórmula:C26H32F3N3O11P2Pureza:99.48% - >99.99%Cor e Forma:SolidPeso molecular:681.49Garetosmab
CAS:<p>Garetosmab (REGN 2477), a human IgG4 monoclonal antibody, inhibits activin A for potential cancer treatment and FOP study.</p>Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:146 kDaROCK inhibitor-2
CAS:<p>ROCK inhibitor-2 is a selective dual inhibitor of ROCK1 and ROCK2 (IC50s of 17 nM and 2 nM, respectively).</p>Fórmula:C21H20N2O2Pureza:99.85%Cor e Forma:SolidPeso molecular:332.4JAK2 Inhibitor V
CAS:<p>JAK2 Inhibitor V (JAK2 Inhibitor V Z3) is a novel specific inhibitor of Jak2, inhibiting Jak2-V617F and Jak2-WT autophosphorylation in a dose-dependent manner.</p>Fórmula:C23H24N2OPureza:98.36% - 99.15%Cor e Forma:SolidPeso molecular:344.45TAK-901
CAS:<p>TAK-901 has been used in trials studying the treatment of Lymphoma, Myelofibrosis, Multiple Myeloma, Myeloid Metaplasia, and Advanced Solid Tumors, among others</p>Fórmula:C28H32N4O3SPureza:99.02% - 99.59%Cor e Forma:SolidPeso molecular:504.64NMS-P715
CAS:<p>NMS-P715 is a highly selective and ATP-competitive MPS1 inhibitor(IC50 of 182 nM).</p>Fórmula:C35H39F3N8O3Pureza:99.84%Cor e Forma:SolidPeso molecular:676.73WDR5-IN-6
CAS:<p>WDR5-IN-6 is a WDR5 inhibitor targeting the WBM locus.WDR5-IN-6 is highly synergistic with OICR-9429, a WDR5 inhibitor that targets the WIN locus.WDR5-IN-6</p>Fórmula:C13H8Cl2N2O2SPureza:99.69%Cor e Forma:SoildPeso molecular:327.19Nefopam hydrochloride
CAS:<p>Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.</p>Fórmula:C17H20ClNOPureza:99.32% - 99.85%Cor e Forma:SolidPeso molecular:289.8Gusacitinib
CAS:<p>Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).</p>Fórmula:C24H28N8O2Pureza:98.06% - 99.94%Cor e Forma:SolidPeso molecular:460.53KY1220
CAS:<p>KY1220 destabilizes both β-catenin and Ras by targeting the Wnt/β-catenin pathway. It has an IC50 of 2.1 μM in HEK293 reporter cells.</p>Fórmula:C14H10N4O3SPureza:99.9%Cor e Forma:SolidPeso molecular:314.32IK-930
CAS:<p>IK-930 is an orally active TEAD inhibitor (EC50 < 0.1 µM) with potent potency.</p>Fórmula:C19H19F3N4O2SPureza:99.89%Cor e Forma:SoildPeso molecular:424.44Golidocitinib
CAS:<p>Golidocitinib (AZD4205) is a selective JAK1 inhibitor (IC50: 73 nM) and weakly inhibits JAK2/JAK3 (IC50: >14.7, >30 μM).</p>Fórmula:C25H31N9O2Pureza:98.87% - 99.88%Cor e Forma:SolidPeso molecular:489.57Silmitasertib sodium salt
CAS:<p>Silmitasertib sodium salt (CX-4945 sodium salt) is a potent and orally bioavailable, highly selective inhibitor of CK2(IC50 of 1 nM, CK2α).</p>Fórmula:C19H11ClN3NaO2Pureza:99.49% - 99.62%Cor e Forma:SolidPeso molecular:371.75JW74
CAS:<p>JW74 antagonizes LiCl-induced activation of the canonical Wnt signaling (IC50: 420 nM).</p>Fórmula:C24H20N6O2SPureza:95.00%Cor e Forma:SolidPeso molecular:456.52E 2012
CAS:<p>E2012 is a γ-secretase modulator (GSM).</p>Fórmula:C25H26FN3O2Pureza:99.18%Cor e Forma:SolidPeso molecular:419.49
