Células - tronco
Os inibidores de células-tronco são compostos que atuam especificamente nas células-tronco e em suas vias de sinalização, afetando sua capacidade de autorrenovação e diferenciação. Esses inibidores são cruciais em pesquisas focadas no controle do comportamento das células-tronco, na compreensão dos processos de desenvolvimento e no desenvolvimento de terapias para doenças como o câncer, onde se acredita que as células-tronco desempenhem um papel fundamental. Na CymitQuimica, oferecemos uma variedade de inibidores de células-tronco para apoiar sua pesquisa em medicina regenerativa, biologia do desenvolvimento e oncologia.
Foram encontrados 486 produtos de "Células - tronco"
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LF3
CAS:<p>LF3 is a specific inhibitor of canonical Wnt signaling by disrupting the interaction between β-catenin and TCF4 (IC50 < 2 μM)</p>Fórmula:C20H24N4O2S2Pureza:99.63%Cor e Forma:SolidPeso molecular:416.56LSKL, Inhibitor of Thrombospondin TSP-1 2TFA
<p>LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .</p>Fórmula:C25H44F6N6O9Pureza:99.75%Cor e Forma:SolidPeso molecular:686.64Fasudil hydrochloride
CAS:<p>Fasudil hydrochloride (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 μM, 1.0 μM, 9.3 μM and 55 μM, respectively.</p>Fórmula:C14H18ClN3O2SPureza:99.54% - ≥95%Cor e Forma:White SolidPeso molecular:327.83Kartogenin
CAS:<p>Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.</p>Fórmula:C20H15NO3Pureza:96.25% - 97.79%Cor e Forma:SolidPeso molecular:317.34TBB
CAS:<p>TBB (NSC-231634)(NSC-231634) is a highly selective, ATP/GTP-competitive inhibitor of casein kinase-2 (CK2).</p>Fórmula:C6HBr4N3Pureza:98.51% - 99.45%Cor e Forma:Off-White SolidPeso molecular:434.71Afuresertib
CAS:<p>Afuresertib (GSK2110183) is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic</p>Fórmula:C18H17Cl2FN4OSPureza:97.51% - 99.51%Cor e Forma:SolidPeso molecular:427.32Itacitinib
CAS:<p>Itacitinib (INCB039110) is an orally bioavailable inhibitor of Janus-associated kinase 1 (JAK1) with potential antineoplastic activity.</p>Fórmula:C26H23F4N9OPureza:96.4% - 99.5%Cor e Forma:SolidPeso molecular:553.51Tofacitinib
CAS:<p>Tofacitinib (Tasocitinib) is an orally Janus kinase inhibitor. Tofacitinib is used for the treatment of rheumatoid arthritis. Cost effective and quality assured.</p>Fórmula:C16H20N6OPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:312.37IWP L6
CAS:<p>IWP L6 (Porcn Inhibitor III) is an extremely effective Porcn inhibitor (EC50: 0.5 nM).</p>Fórmula:C25H20N4O2S2Pureza:99.51% - >99.99%Cor e Forma:SolidPeso molecular:472.58PF-4800567
CAS:<p>PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.</p>Fórmula:C17H18ClN5O2Pureza:99.76%Cor e Forma:SolidPeso molecular:359.81ETC-159
CAS:<p>ETC-159 (ETC-1922159) is a potent, orally available PORCN inhibitor. It inhibits β-catenin reporter activity with an IC50 of 2.9 nM.</p>Fórmula:C19H17N7O3Pureza:96.87% - 99.30%Cor e Forma:SolidPeso molecular:391.38BML-284 hydrochloride
CAS:<p>BML-284 hydrochloride (Wnt agonist 1 HCL) is a potent, selective Wnt canonical signaling activator and tubulin polymerization inhibitor.</p>Fórmula:C19H19ClN4O3Pureza:99.80%Cor e Forma:SolidPeso molecular:386.84LH846
CAS:<p>LH846 is a selective inhibitor of CK1δ (IC50 values are 290 nM, 1.3 uM and 2.5 uM for CK1δ, ε and α); exhibits no inhibitory activity at CK2.</p>Fórmula:C16H13ClN2OSPureza:90% - 98.26%Cor e Forma:SolidPeso molecular:316.81Stafia-1
CAS:<p>Stafia-1 is a potent STAT5a inhibitor ( IC50=22.2 μM). Stafia-1 displays high selectivity over STAT5b and other STAT family members.</p>Fórmula:C24H27O10PPureza:98.08%Cor e Forma:SolidPeso molecular:506.44SR-3677
CAS:<p>SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).</p>Fórmula:C22H24N4O4Pureza:98.46%Cor e Forma:SolidPeso molecular:408.45WAY-262611
CAS:<p>WAY262611 is a Wnt/β-catenin agonist and an inhibitor of Dkk1. It increases bone formation rate with EC50 of 0.63 μM in TCF-luciferase assay.</p>Fórmula:C20H22N4Pureza:98.09% - 99.09%Cor e Forma:SolidPeso molecular:318.42PF-04802367
CAS:<p>PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.</p>Fórmula:C16H16ClN5O3Pureza:98.76%Cor e Forma:SolidPeso molecular:361.78Solcitinib
CAS:<p>Solcitinib (GLPG-0778), a JAK1 inhibitor, may treat psoriasis, ulcerative colitis, and lupus.</p>Fórmula:C22H23N5O2Pureza:99.61% - 99.82%Cor e Forma:SolidPeso molecular:389.45TED-347
CAS:<p>TED-347 is an irreversible and covalent inhibitor of TEAD4-Yap1 protein-protein interaction(EC50 of 5.9 μM), and inhibits glioblastoma cell viability.</p>Fórmula:C15H11ClF3NOPureza:99.9%Cor e Forma:SolidPeso molecular:313.7SD-208
CAS:<p>SD-208 (ALK5 Inhibitor V), a selective TGF-βRI (ALK5) inhibitor (IC50: 48 nM), is >100-fold selectivity over TGF-βRII.</p>Fórmula:C17H10ClFN6Pureza:98.72% - 99.65%Cor e Forma:SolidPeso molecular:352.75
