Células - tronco
Os inibidores de células-tronco são compostos que atuam especificamente nas células-tronco e em suas vias de sinalização, afetando sua capacidade de autorrenovação e diferenciação. Esses inibidores são cruciais em pesquisas focadas no controle do comportamento das células-tronco, na compreensão dos processos de desenvolvimento e no desenvolvimento de terapias para doenças como o câncer, onde se acredita que as células-tronco desempenhem um papel fundamental. Na CymitQuimica, oferecemos uma variedade de inibidores de células-tronco para apoiar sua pesquisa em medicina regenerativa, biologia do desenvolvimento e oncologia.
Foram encontrados 482 produtos de "Células - tronco"
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BDP5290
CAS:<p>BDP5290 is a potent inhibitor of both ROCK and MRCK(IC50s of 5 nM, 50 nM, 10 nM and 100 nM for ROCK1, ROCK2, MRCKα and MRCKβ, respectively.)</p>Fórmula:C17H18ClN7OPureza:97.22%Cor e Forma:SolidPeso molecular:371.82Lats-IN-1
CAS:<p>Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues.</p>Fórmula:C18H14N4OSPureza:97.54% - 99.79%Cor e Forma:SolidPeso molecular:334.39YO-01027
CAS:<p>YO-01027 (DBZ) is a potent γ-secretase inhibitor.</p>Fórmula:C26H23F2N3O3Pureza:97.21% - 99.58%Cor e Forma:SolidPeso molecular:463.48LY3200882
CAS:<p>LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).</p>Fórmula:C24H29N5O3Pureza:99.46% - 99.63%Cor e Forma:SolidPeso molecular:435.52exo-IWR-1
CAS:<p>exo-IWR-1 (exo-IWR 1) is an inactive stereoisomer of Endo-IWR-1,and is a negative control of IWR-1. IWR-1 is a tankyrase inhibitor which inhibits Wnt/β-catenin</p>Fórmula:C25H19N3O3Pureza:97.41%Cor e Forma:SolidPeso molecular:409.44ZINC00881524
CAS:<p>ZINC00881524 (ROCK inhibitor) is an effective and specific ROCK inhibitor.</p>Fórmula:C21H20N2O3SPureza:99.48%Cor e Forma:SolidPeso molecular:380.46AS1517499
CAS:<p>AS1517499 is a blood-brain barrier permeable inhibitor of STAT6 phosphorylation (IC50= 21 nM). High-Quality, Low-Cost!</p>Fórmula:C20H20ClN5O2Pureza:98.27% - 98.7%Cor e Forma:SolidPeso molecular:397.86Epiblastin A
CAS:Epiblastin A inhibits CK1, targets its isoenzymes, and converts EpiSCs to cESCs.Fórmula:C12H10ClN7Pureza:99.45%Cor e Forma:SolidPeso molecular:287.71BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Fórmula:C14H13N3OSPureza:99.02%Cor e Forma:SolidPeso molecular:271.34Wnt-C59
CAS:<p>Wnt-C59 (C59)(C59) is a highly effective and specific Wnt signaling antagonis with PORCN enzymatic activity.</p>Fórmula:C25H21N3OPureza:99.56% - 99.95%Cor e Forma:SolidPeso molecular:379.45IMR-1A
CAS:IMR-1A is the metabolite of IMR-1 which is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.Fórmula:C13H11NO5S2Pureza:97.1% - 99.76%Cor e Forma:SolidPeso molecular:325.36KYA1797K
CAS:KYA1797K is a highly potent and selective inhibitor. Wnt/β-catenin IC50 is 0.75 μM through TOPflash assay.Fórmula:C17H11N2O6S2·KPureza:97.57% - 99.33%Cor e Forma:SolidPeso molecular:442.51BMS986260
CAS:<p>BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).</p>Fórmula:C18H12ClFN6OPureza:97.67%Cor e Forma:SolidPeso molecular:382.78IMR-1
CAS:<p>IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 μMol/L.</p>Fórmula:C15H15NO5S2Pureza:97.96% - 98.38%Cor e Forma:SolidPeso molecular:353.41BMP signaling agonist sb4
CAS:<p>BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)</p>Fórmula:C14H10BrNOSPureza:99.48% - 99.805%Cor e Forma:SolidPeso molecular:320.2Fz7-21
CAS:<p>Fz7-21, a peptide antagonist of FZD7, inhibits Wnt/β-catenin signaling (IC50=50-100nM) in cells with WNT3A.</p>Fórmula:C83H114N18O23S2Pureza:99.8%Cor e Forma:SolidPeso molecular:1796.03I3MT-3
CAS:<p>I3MT-3 (HMPSNE) is a selective inhibitor of 3MST, targeting active site cysteine residues and permeating cell membranes.</p>Fórmula:C17H14N2O2SPureza:99.76%Cor e Forma:SolidPeso molecular:310.37XMU-MP-1
CAS:<p>XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!</p>Fórmula:C17H16N6O3S2Pureza:99.68% - 99.79%Cor e Forma:SolidPeso molecular:416.48RKI-1447
CAS:RKI-1447 is a potent inhibitor of ROCK1 and ROCK2. It has anti-invasive and antitumor activities.Fórmula:C16H14N4O2SPureza:98% - 99.73%Cor e Forma:SolidPeso molecular:326.37LY900009
CAS:<p>LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.</p>Fórmula:C23H27N3O4Pureza:97.07%Cor e Forma:SolidPeso molecular:409.48
