Via Hippo
Os inibidores da via Hippo são compostos que têm como alvo e inibem componentes da via de sinalização Hippo, que desempenha um papel crucial na regulação do crescimento celular, proliferação e apoptose. A desregulação da via Hippo tem sido implicada no desenvolvimento do câncer e na função das células-tronco. Inibidores dessa via são valiosos para estudar os mecanismos de controle do tamanho dos órgãos, regeneração de tecidos e progressão do câncer. Na CymitQuimica, oferecemos inibidores da via Hippo para apoiar sua pesquisa em sinalização celular, oncologia e medicina regenerativa.
Foram encontrados 8 produtos de "Via Hippo"
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MR24
CAS:MR24 is a derivative of G-5555 and acts as an inhibitor of mammalian STE20-like (MST) kinases. It selectively targets MST3 and MST4, with EC50 values of 57 nM and 583 nM, respectively.Fórmula:C26H29ClN6O3Peso molecular:509.00α-Ionone (Standard)
CAS:alpha-Ionone (Standard) is the standard substance of alpha-Ionone, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. alpha-Ionone is a natural product for research related to life sciences. The catalog number is TN3385 and the CAS number is 127-41-3.Fórmula:C13H20OPeso molecular:192.30XMU-MP-1
CAS:XMU-MP-1 is a reversible and selective MST1/2 kinase inhibitor, IC50 values for MST1 and MST2 are 71.1 nM and 38.1 nM, respectively. High-Quality, Low-Cost!Fórmula:C17H16N6O3S2Pureza:99.68% - 99.86%Cor e Forma:SolidPeso molecular:416.48Ref: TM-T4212
1mg52,00€2mg79,00€5mg97,00€10mg153,00€25mg305,00€50mg512,00€100mg663,00€1mL*10mM (DMSO)95,00€I3MT-3
CAS:I3MT-3 (HMPSNE) is a selective inhibitor of 3MST, targeting active site cysteine residues and permeating cell membranes.Fórmula:C17H14N2O2SPureza:99.76%Cor e Forma:SolidPeso molecular:310.37Pim1/AKK1-IN-1
CAS:Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.Fórmula:C20H13N5OPureza:97.03% - 98.69%Cor e Forma:SolidPeso molecular:339.35Ref: TM-T5093
1mg85,00€2mg124,00€5mg173,00€10mg263,00€25mg464,00€50mg672,00€100mg945,00€1mL*10mM (DMSO)192,00€JA310
CAS:JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].Fórmula:C17H19N7OCor e Forma:SolidPeso molecular:337.38EMT inhibitor-1
CAS:EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.Fórmula:C12H12Cl2N2O2SPureza:99.53%Cor e Forma:SolidPeso molecular:319.21Ref: TM-T11190
1mg111,00€5mg264,00€10mg424,00€25mg723,00€50mg1.008,00€100mg1.378,00€500mg2.737,00€1mL*10mM (DMSO)283,00€IHMT-MST1-58
CAS:IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity.
Fórmula:C21H22N6O3SPureza:98.31% - 99.92%Cor e Forma:SolidPeso molecular:438.5
