ALK
Os inibidores de ALK são compostos que especificamente visam e inibem a quinase do linfoma anaplásico (ALK), uma tirosina quinase receptora envolvida no desenvolvimento e progressão de certos cânceres, incluindo o câncer de pulmão de células não pequenas e o neuroblastoma. Ao inibir ALK, esses compostos bloqueiam vias de sinalização que promovem o crescimento e a sobrevivência das células tumorais. Na CymitQuimica, oferecemos inibidores de ALK para apoiar sua pesquisa em oncologia, terapias direcionadas contra o câncer e transdução de sinal.
Foram encontrados 112 produtos de "ALK"
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N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-bromoaniline
CAS:<p>Compound 12d is a potent ALK5 inhibitor with an IC50 of 7nM.</p>Fórmula:C22H18BrN7Pureza:99.935%Cor e Forma:SolidPeso molecular:460.33CH5424802 analog
CAS:<p>CH5424802 analog is a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant.</p>Fórmula:C28H30N4O2Pureza:98.96%Cor e Forma:SolidPeso molecular:454.56DMH-1
CAS:<p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>Fórmula:C24H20N4OPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:380.44ALK kinase inhibitor-1
CAS:<p>SAR348830 is an ALK inhibitor, targeting anaplastic lymphoma kinase.</p>Fórmula:C28H32FN5O3SPureza:99.84%Cor e Forma:SolidPeso molecular:537.65CEP-28122 mesylate salt
<p>CEP-28122 mesylate, a diaminopyrimidine, selectively inhibits ALK with IC50 of 1.9 nM and exhibits antitumor effects.</p>Fórmula:C29H39ClN6O6SCor e Forma:SolidPeso molecular:635.17AZD-3463
CAS:<p>AZD-3463 (ALK/IGF1R inhibitor) , an orally bioavailable ALK inhibitor (Ki: 0.75 nM), can inhibit IGF1R with equivalent potency.</p>Fórmula:C24H25ClN6OPureza:99.13%Cor e Forma:SolidPeso molecular:448.95Crizotinib acetate
CAS:<p>Crizotinib is an oral c-met/HGFR tyrosine kinase inhibitor with potential cancer-fighting properties.</p>Fórmula:C23H26Cl2FN5O3Cor e Forma:SolidPeso molecular:510.39K02288
CAS:<p>K 02288 is a novel small molecule inhibitor of ALK1/2/3/6.</p>Fórmula:C20H20N2O4Pureza:98% - 99.83%Cor e Forma:SolidPeso molecular:352.38CEP-28122
CAS:<p>CEP-28122 is a highly potent and selective orally active ALK inhibitor.</p>Fórmula:C28H35ClN6O3Pureza:99.87% - >99.99%Cor e Forma:SolidPeso molecular:539.07Vactosertib
CAS:<p>Vactosertib (EW-7197) is an oral TGFBR1/ALK5 inhibitor with potential cancer-fighting properties.</p>Fórmula:C22H18FN7Pureza:98.85% - 99.81%Cor e Forma:SolidPeso molecular:399.42CAY10594
CAS:<p>CAY10594, a PLD2 inhibitor, mitigates acetaminophen liver damage via the p-GSK-3β/JNK pathway.</p>Fórmula:C26H28N4O2Pureza:98%Cor e Forma:SolidPeso molecular:428.53LDN-214117
CAS:<p>LDN-214117 is a potent and selective ALK2 inhibitor.</p>Fórmula:C25H29N3O3Pureza:98% - 99.82%Cor e Forma:SolidPeso molecular:419.52LDN193189
CAS:<p>LDN193189 blocks BMP signaling by inhibiting ALK2/3; IC50: ALK1/2/3/6 = 0.8/0.8/5.3/16.7 nM.</p>Fórmula:C25H22N6Pureza:98% - 99.86%Cor e Forma:SolidPeso molecular:406.48BIBF0775
CAS:<p>BIBF0775 is a selective TGFβ type I receptor (Alk5) inhibitor (IC50: 34 nM).</p>Fórmula:C31H34N4O2Pureza:99.45% - 99.79%Cor e Forma:SolidPeso molecular:494.63A 83-01
CAS:<p>A 83-01 (ALK5 Inhibitor IV) is a selective inhibitor of TGF-β type I receptor ALK5 kinase, type I activin/nodal receptor ALK4 and type I nodal receptor ALK7.</p>Fórmula:C25H19N5SPureza:97% - 98.2%Cor e Forma:SolidPeso molecular:421.52SB-505124
CAS:<p>SB505124 is a selective inhibitor of TGFβR for ALK4, ALK5.</p>Fórmula:C20H21N3O2Pureza:97.19% - 99.92%Cor e Forma:SolidPeso molecular:335.4Alectinib hydrochloride
CAS:<p>Alectinib hydrochloride (RO5424802 Hydrochloride) is a selective, and orally available inhibitor of ALK( IC50 : 1.9 nM)</p>Fórmula:C30H35ClN4O2Pureza:99.61% - 99.96%Cor e Forma:SolidPeso molecular:519.08Ensartinib
CAS:<p>Ensartinib (X-396) is a potent and orally active dual ALK/MET inhibitor for the treatment of ALK-positive non-small cell lung cancer (NSCLC).</p>Fórmula:C26H27Cl2FN6O3Pureza:99.92%Cor e Forma:SolidPeso molecular:561.44HG-14-10-04
CAS:<p>HG-14-10-04 is a potent and specific ALK inhibitor.</p>Fórmula:C29H34ClN7OPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:532.08SB-431542
CAS:<p>SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective.</p>Fórmula:C22H16N4O3Pureza:99.035% - >99.99%Cor e Forma:SolidPeso molecular:384.39
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