HER
Os inibidores de HER são compostos que bloqueiam a atividade dos receptores do fator de crescimento epidérmico humano, particularmente o HER2, que está superexpresso em certos cânceres de mama e outras malignidades. A inibição das vias de sinalização HER é uma estratégia-chave nas terapias oncológicas direcionadas. Na CymitQuimica, oferecemos inibidores de HER para apoiar sua pesquisa em oncologia, terapias direcionadas e sinalização celular.
Foram encontrados 12 produtos para "HER".
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Panomifene HCl
CAS:Panomifene HCl is a selective anti-estrogenic compound with antitumor activity for the treatment of breast cancer.Fórmula:C25H25ClF3NO2Pureza:99.53%Cor e Forma:SolidPeso molecular:463.92Trastuzumab β
CAS:Trastuzumab beta (ABP 980), a biosimilar McAb, targets HER2 for HER2+ breast and gastric cancer research.Cor e Forma:LiquidHER2/neu (654-662) GP2 acetate
GP2 acetate, from HER2 (654-662), triggers HLA-A2-restricted T cells to attack epithelial cancers.Fórmula:C44H81N9O13Pureza:98%Cor e Forma:SolidPeso molecular:944.17Ref: TM-TP1583L
1mg175,00€5mg394,00€10mg590,00€25mg1.060,00€50mg1.591,00€100mg2.387,00€200mg3.580,00€Coprelotamab
CAS:Coprelotamab is a humanized mAb targeting HER2 that inhibits tumor growth by blocking receptor dimerization and mediating ADCC, used for HER2-positive cancer research.Pureza:95%Cor e Forma:Transparent LiquidABP-102
ABP-102 (CT P72) is a bispecific t-cell adduct (BiTE) that acts as a CD3 modulator and selective HER2 modulator for targeting HER2 overexpressing tumors.Cor e Forma:Odour LiquidPF04929113
CAS:PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.Fórmula:C25H30F3N5O4Pureza:99.04%Cor e Forma:SolidPeso molecular:521.53Ref: TM-T6341
1mg37,00€2mg50,00€5mg79,00€1mL*10mM (DMSO)92,00€10mg113,00€25mg177,00€50mg334,00€100mg500,00€PF-04929113 Mesylate
CAS:PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37Fórmula:C26H34F3N5O7SPureza:99% - 99.46%Cor e Forma:SolidPeso molecular:617.63Ref: TM-T4342
1mg73,00€2mg95,00€5mg150,00€1mL*10mM (DMSO)220,00€10mg273,00€25mg396,00€50mg583,00€100mg832,00€500mg1.684,00€BMS 599626 2HCl
CAS:BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100Fórmula:C27H29FN8O3Cl2Pureza:99.94%Cor e Forma:SoildPeso molecular:603.48Zanidatamab
CAS:Zanidatamab (ZW25) is a bispecific, humanized monoclonal antibody that targets two distinct epitopes (ECD2 and ECD4) of the HER2 receptor, exhibiting anti-tumorPureza:95%Cor e Forma:Transparent LiquidAnbenitamab
CAS:Anbenitamab (KN-026) is a HER2 biparatopic bispecific antibody that exerts potent anti-tumor efficacy by inhibiting HER2 signaling and mediating ADCC.Cor e Forma:LiquidCinrebafusp alfa
CAS:Cinrebafusp alfa is a CD137/HER2 bispecific antibody mediating T cell co-stimulation, with potential in HER2-positive solid tumor research.Pureza:95%Cor e Forma:LiquidHER2-IN-12
CAS:HER2-IN-12 is a selective HER2 inhibitor; blocks autophosphorylation; inhibits signaling; breast cancer research.Fórmula:C17H18BrN5O2SCor e Forma:SolidPeso molecular:436.33
