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HER

HER

Os inibidores de HER são compostos que bloqueiam a atividade dos receptores do fator de crescimento epidérmico humano, particularmente o HER2, que está superexpresso em certos cânceres de mama e outras malignidades. A inibição das vias de sinalização HER é uma estratégia-chave nas terapias oncológicas direcionadas. Na CymitQuimica, oferecemos inibidores de HER para apoiar sua pesquisa em oncologia, terapias direcionadas e sinalização celular.

Foram encontrados 10 produtos para "HER".

  • Panomifene HCl
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    Panomifene HCl

    CAS:
    Panomifene HCl is a selective anti-estrogenic compound with antitumor activity for the treatment of breast cancer.
    Fórmula:C25H25ClF3NO2
    Pureza:99.53%
    Cor e Forma:Solid
    Peso molecular:463.92

    Ref: TM-T33876L

  • HER2/neu (654-662) GP2 acetate
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    HER2/neu (654-662) GP2 acetate

    GP2 acetate, from HER2 (654-662), triggers HLA-A2-restricted T cells to attack epithelial cancers.
    Fórmula:C44H81N9O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:944.17

    Ref: TM-TP1583L

  • Coprelotamab
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    Coprelotamab

    CAS:
    Coprelotamab is a humanized mAb targeting HER2 that inhibits tumor growth by blocking receptor dimerization and mediating ADCC, used for HER2-positive cancer research.
    Pureza:95%
    Cor e Forma:Transparent Liquid

    Ref: TM-T80596

  • Logotipo do CymitQuimica
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    Trastuzumab-anns

    CAS:
    Trastuzumab-anns is a biosimilar of Herceptin and a monoclonal antibody targeting HER2 that is used for HER2-positive breast cancer and gastric cancer.
    Pureza:95%
    Cor e Forma:Liquid
    Peso molecular:~150 kDa

    Ref: TM-T76971

  • PF-04929113 Mesylate
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    PF-04929113 Mesylate

    CAS:
    PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37
    Fórmula:C26H34F3N5O7S
    Pureza:99% - 99.46%
    Cor e Forma:Solid
    Peso molecular:617.638

    Ref: TM-T4342

  • PF04929113
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    PF04929113

    CAS:
    PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.
    Fórmula:C25H30F3N5O4
    Pureza:99.04%
    Cor e Forma:Solid
    Peso molecular:521.532

    Ref: TM-T6341

  • BMS 599626 2HCl
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    BMS 599626 2HCl

    CAS:
    BMS 599626 2HCl (873837-23-1(HCl)) (AC480 dihydrochloride) is a selective inhibitor of HER1 and HER2 (IC50s: 20 nM and 30 nM), ~8-fold less potent to HER4, >100
    Fórmula:C27H29FN8O3Cl2
    Pureza:99.94%
    Cor e Forma:Soild
    Peso molecular:603.48

    Ref: TM-T5398

  • Anbenitamab
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    Anbenitamab

    CAS:
    Anbenitamab (KN-026) is a HER2 biparatopic bispecific antibody that exerts potent anti-tumor efficacy by inhibiting HER2 signaling and mediating ADCC.
    Cor e Forma:Liquid

    Ref: TM-T76905

  • Logotipo do CymitQuimica
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    Cinrebafusp alfa

    CAS:
    Cinrebafusp alfa is a CD137/HER2 bispecific antibody mediating T cell co-stimulation, with potential in HER2-positive solid tumor research.
    Pureza:95%
    Cor e Forma:Liquid

    Ref: TM-T80590

  • HER2-IN-12
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    HER2-IN-12

    CAS:
    HER2-IN-12 is a selective HER2 inhibitor; blocks autophosphorylation; inhibits signaling; breast cancer research.
    Fórmula:C17H18BrN5O2S
    Cor e Forma:Solid
    Peso molecular:436.33

    Ref: TM-T62487