VEGFR
Os inibidores do Receptor do Fator de Crescimento Endotelial Vascular (VEGFR) são compostos que bloqueiam a sinalização do VEGFR, um receptor chave na via VEGF, crucial para a angiogênese. Os inibidores de VEGFR impedem a formação de novos vasos sanguíneos que fornecem nutrientes e oxigênio aos tumores, inibindo assim o crescimento tumoral. Esses inibidores são amplamente utilizados na terapia contra o câncer e na pesquisa para estudar os mecanismos da angiogênese e desenvolver tratamentos anticâncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de VEGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 242 produtos de "VEGFR"
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Regorafenib
CAS:Fórmula:C21H15ClF4N4O3Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:482.82Sorafenib Tosylate
CAS:Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:637.03SKLB1002
CAS:Fórmula:C13H12N4O2S2Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:320.39NVP-BHG 712
CAS:Fórmula:C26H20F3N7OPureza:>95.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:503.49Axitinib
CAS:Fórmula:C22H18N4OSPureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:386.472-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
100gA consultar10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€1g131,00€5g255,00€50g617,00€10g619,00€Sunitinib
CAS:Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).Fórmula:C22H27FN4O2Pureza:98% - 99.67%Cor e Forma:Yellow SolidPeso molecular:398.47Albendazole
CAS:Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.Fórmula:C12H15N3O2SPureza:98.21% - 98.76%Cor e Forma:Colorless Crystals SolidPeso molecular:265.33Chloropyramine hydrochloride
CAS:Chloropyramine hydrochloride (Alergosan) is a histamine receptor H1 antagonist.Fórmula:C16H20ClN3·HClPureza:99.45% - 99.8%Cor e Forma:SolidPeso molecular:326.26Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:White PowderPeso molecular:437.52Ref: TM-T0097L
1mL*10mM (DMSO)33,00€10mg42,00€25mg66,00€50mg90,00€100mg137,00€200mg225,00€500mg313,00€Ref: IN-DA01DU9U
100mgA consultar250mgA consultar2mg112,00€10mg156,00€5mg161,00€25mg310,00€50mg701,00€Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Fórmula:C22H18N4OSPureza:98.9% - 99.74%Cor e Forma:Off-White SolidPeso molecular:386.47PTC299
CAS:PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNAFórmula:C25H20Cl2N2O3Pureza:99.72%Cor e Forma:SolidPeso molecular:467.34Ref: TM-T12574
1mg111,00€5mg230,00€1mL*10mM (DMSO)236,00€10mg350,00€25mg590,00€50mg838,00€100mg1.144,00€Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Cor e Forma:SolidPeso molecular:426.85(E)-2-Cyano-3-(4-hydroxy-3,5-diisopropylphenyl)-N-(3-phenylpropyl)acrylamide
CAS:Fórmula:C25H30N2O2Pureza:98%Cor e Forma:SolidPeso molecular:390.51792H-Indol-2-one, 3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylene]-1,3-dihydro-
CAS:Fórmula:C15H14N2OPureza:98%Cor e Forma:SolidPeso molecular:238.2845Icrucumab
CAS:Icrucumab, a humanized antibody, inhibits VEGFR-1 and shows antitumor effects, tested in metastatic colon cancer.Pureza:> 95%Cor e Forma:LiquidPeso molecular:150 kDaParsatuzumab
CAS:Parsatuzumab (RG 7414), a monoclonal antibody targeting EGFL7, an immunomodulator.Parsatuzumab inhibits the interaction of EGFL7 with endothelial cells.Pureza:> 95% - > 95%Cor e Forma:LiquidPeso molecular:148.22 kDaGW806742X
CAS:GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.Fórmula:C25H22F3N7O4SPureza:98.3%Cor e Forma:SolidPeso molecular:573.55Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Fórmula:C21H16ClF3N4O3Pureza:98% - 99.89%Cor e Forma:SolidPeso molecular:464.82Naphazoline hydrochloride
CAS:Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.Fórmula:C14H15ClN2Pureza:97.93%Cor e Forma:White Crystalline Powder White Crystalline PowderPeso molecular:246.74Lucitanib
CAS:Lucitanib (E-3810) is a VEGFR/FGFR inhibitor targeting VEGFR1-3 and FGFR1-2 with IC50s 7-82.5 nM.Fórmula:C26H25N3O4Pureza:96.13%Cor e Forma:SolidPeso molecular:443.49Ref: TM-T15185
1mg46,00€2mg59,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg137,00€25mg255,00€50mg462,00€100mg672,00€Chloramphenicol
CAS:Chloramphenicol (Chloromycetin) is a broad-spectrum antibiotic that inhibits the biosynthesis of bacterial proteins. Cost-effective and quality-assured.
Fórmula:C11H12Cl2N2O5Pureza:99.6% - 99.84%Cor e Forma:Needles Or Elongated Plates From Water Or Ethylene Dichloride SolidPeso molecular:323.13Sorafenib tosylate
CAS:Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:99.24% - 99.94%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:637.03Pamufetinib
CAS:Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase.Fórmula:C27H23FN4O4SPureza:99.39%Cor e Forma:SolidPeso molecular:518.56Ref: TM-T13108
1mg52,00€5mg101,00€1mL*10mM (DMSO)127,00€10mg149,00€25mg244,00€50mg359,00€100mg510,00€200mg695,00€Sunitinib Malate
CAS:Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Fórmula:C26H33FN4O7Pureza:98% - 99.26%Cor e Forma:SolidPeso molecular:532.56Acrizanib
CAS:Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2.Fórmula:C20H18F3N7O2Pureza:98.71% - 99.64%Cor e Forma:SolidPeso molecular:445.4Ref: TM-T5373
1mg105,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg401,00€25mg685,00€50mg954,00€100mg1.243,00€Motesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFórmula:C22H23N5O·2H3PO4Pureza:99.69%Cor e Forma:SolidPeso molecular:569.44VEGFR-2-IN-31
VEGFR-2-IN-31 (compound 3i), a robust VEGFR-2 inhibitor (IC50=8.93 nM), serves as an anti-prostate cancer agent by arresting the cell cycle at the S-phase andFórmula:C15H10F2N4OPureza:98%Cor e Forma:SolidPeso molecular:300.265Z-7-Oxozeaenol
CAS:5Z-7-Oxozeaenol: TGF-β-activated kinase 1 inhibitor, IC50 8.1 nM; VEGF-R2 inhibitor, IC50 52 nM; weak MEK1 inhibitor, IC50 411 nM.Fórmula:C19H22O7Pureza:99%Cor e Forma:SolidPeso molecular:362.37VEGF-IN-1
VEGF-IN-1 (compound 6) reduces the release of VEGF in U87-MG cells and inhibits angiogenesis in vitro. Additionally, it suppresses cell proliferation by inducing autophagy in tumor cells, with an IC50 value of 28.35 μM against U87-MG cells.Fórmula:C27H22Cl2N4RuCor e Forma:SolidPeso molecular:574.47VEGFR-2-IN-29
CAS:VEGFR-2-IN-29 is a VEGFR2 inhibitor.Fórmula:C16H11N3O3Pureza:99.59%Cor e Forma:SolidPeso molecular:293.28VEGFR-2-IN-59
VEGFR-2-IN-59 (Compound 3h) is an inhibitor of VEGFR2 with an IC50 of 3.73 µM. It exhibits cytotoxicity in cancer cell lines A549, HT-29, A375, MCF7, and NHDF, with IC50 values of 20.91, 19.70, 9.63, 17.43, and 20.71 μM, respectively. VEGFR-2-IN-59 also inhibits tubular structure formation and demonstrates anti-angiogenic properties.Fórmula:C19H20N6O4Cor e Forma:SolidPeso molecular:396.4VEGFR-2-IN-35
VEGFR-2-IN-35 (compound 7) is a potent inhibitor of VEGFR-2, exhibiting an IC50 of 37 nM.Fórmula:C25H19N3O3Pureza:98%Cor e Forma:SolidPeso molecular:409.44Tyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCor e Forma:Odour SolidRef: TM-L2200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarAngiogenesis related Compound Library
A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and highCor e Forma:Odour SolidRef: TM-L4800
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarAbicipar pegol
CAS:Abicipar pegol is an anti-VEGF DARPin for ocular diseases, reducing retinal thickness and leakage.Cor e Forma:LiquidFDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Cor e Forma:LiquidPulocimab
CAS:Pulocimab, an anti-VEGFR2 monoclonal antibody (mAb), is utilized in cancer research [1].Cor e Forma:LiquidTovecimig
Tovecimig is a G1-scFvlh_L-κ type bispecific antibody targeting VEGFA/DLL4.Cor e Forma:Odour LiquidKinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Cor e Forma:Odour SolidRef: TM-L1600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarVEGFR-2-IN-55
VEGFR-2-IN-55 (Compound 30) is an effective VEGFR-2 kinase inhibitor with an IC50 of 1.24 nM and exhibits anti-tumor activity.Cor e Forma:Odour SolidConbercept
CAS:Conbercept (KH902) is a fusion protein comprising the second immunoglobulin C-like domain of FLT1 and the third and fourth immunoglobulin C-like domains of KDRPureza:98%Cor e Forma:LiquidOlinvacimab
CAS:Olinvacimab (TTAC-0001) is a human monoclonal antibody targeting VEGFR-2/KDR with anti-angiogenic activity that blocks tumor angiogenesis.Pureza:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:148.16 kDaProtein LMWP
CAS:Protein LMWP, a cell-penetrating peptide, exhibits inhibitory activity against vascular endothelial growth factor (VEGF), and is utilized in cancer research forFórmula:C72H142N44O16Pureza:98%Cor e Forma:SolidPeso molecular:1880.18KLTWQELYQLKYKGI
CAS:KLTWQELYQLKYKGI (QK) is a VEGF-mimicking peptide that competes with VEGF by binding to its receptors.Fórmula:C92H143N21O23Pureza:98%Cor e Forma:SolidPeso molecular:1911.25Arginyl-Glutamine
CAS:Arginyl-Glutamine (Arg-Gln) is a dipeptide nutritional supplement that protects neonatal mice from hyperoxia-induced lung injury, lowering VEGF levels.Fórmula:C11H22N6O4Pureza:95.2%Cor e Forma:SolidPeso molecular:302.33
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