VEGFR
Os inibidores do Receptor do Fator de Crescimento Endotelial Vascular (VEGFR) são compostos que bloqueiam a sinalização do VEGFR, um receptor chave na via VEGF, crucial para a angiogênese. Os inibidores de VEGFR impedem a formação de novos vasos sanguíneos que fornecem nutrientes e oxigênio aos tumores, inibindo assim o crescimento tumoral. Esses inibidores são amplamente utilizados na terapia contra o câncer e na pesquisa para estudar os mecanismos da angiogênese e desenvolver tratamentos anticâncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de VEGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 245 produtos de "VEGFR"
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BMS-690514
CAS:BMS-690514 is a potent and orally active inhibitor of EGFR and VEGFR. It has IC50s of 5, 20 and 60 nM for EGFR, HER 2 and HER 4, respectively.Fórmula:C19H24N6O2Pureza:99.08%Cor e Forma:SolidPeso molecular:368.43Brivanib (alaninate)
CAS:Brivanib Alaninate (BMS-582664) is an alaninate salt of a vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with potential antineoplastic effect.Fórmula:C22H24FN5O4Pureza:99.46% - 99.66%Cor e Forma:SolidPeso molecular:441.46Tarcocimab
CAS:Tarcocimab (OG1953) is a humanized IgG1 monoclonal antibody targeting VEGFA, researched for RVO and wet AMD.Cor e Forma:LiquidZM323881 hydrochloride
CAS:ZM323881 hydrochloride (ZM 323881 HCl) is a potent and selective VEGFR2 inhibitor.Fórmula:C22H19ClFN3O2Pureza:99.43%Cor e Forma:SolidPeso molecular:411.86Ref: TM-T1991
1mg35,00€5mg70,00€10mg101,00€25mg236,00€50mg389,00€100mg582,00€200mg823,00€1mL*10mM (DMSO)72,00€Bucillamine
CAS:Bucillamine (DE019) protects against Ischemia/reperfusion injury in high-risk organ transplants and inhibits the production of VEGF.Fórmula:C7H13NO3S2Pureza:99.47%Cor e Forma:SolidPeso molecular:223.31E3330
CAS:E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity.Fórmula:C21H30O6Pureza:99.52%Cor e Forma:SolidPeso molecular:378.46VEGFR-2-IN-6
CAS:VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis [1].Fórmula:C20H21N7O2SPureza:99.01%Cor e Forma:SolidPeso molecular:423.49Naphazoline
CAS:Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity.Fórmula:C14H14N2Pureza:99.79%Cor e Forma:White Crystalline Powder SolidPeso molecular:210.27DMH4
CAS:DMH4 is a potent and selective inhibitor of VEGFR2 with an IC50 of 0.16 µM.Fórmula:C24H24N4O2Pureza:99.58%Cor e Forma:SolidPeso molecular:400.47AMG-Tie2-1
CAS:AMG-Tie2-1 is a Tie2 and VEGFR2 inhibitor with anticancer and antitumor activity for the study of cardiovascular disease and cancer.Fórmula:C25H20F3N5O2Pureza:98.9%Cor e Forma:SolidPeso molecular:479.45(E)-FeCP-oxindole
CAS:(E)-FeCP-oxindole 是一种 VEGFR2 抑制剂，IC50 为 214 nM。Fórmula:C19H15FeNOPureza:99.85%Cor e Forma:SolidPeso molecular:329.17Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.
Fórmula:C27H21N3O3Pureza:99.22%Cor e Forma:SolidPeso molecular:435.47VEGFR-3-IN-1
CAS:VEGFR-3-IN-1, a potent VEGFR3 inhibitor (IC50=110.4 nM), hinders tumor growth and VEGFR3 signaling, affecting HDLEC and MDA-MB cell proliferation/migration.Fórmula:C29H29ClF3N7OSPureza:99.95%Cor e Forma:SolidPeso molecular:616.1Pz-1
CAS:Pz-1 is an inhibitor of VEGFR2 and RET (rearranged during transfection) tyrosine kinase that blocks the blood supply required for RET-stimulated growth.Fórmula:C26H26N6O2Pureza:99.89%Cor e Forma:SolidPeso molecular:454.52(Z)-FeCP-oxindole
CAS:(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for human. (Z)-FeCP-oxindole shows anticancer activity.Fórmula:C19H15FeNOPureza:99.63% - 99.84%Cor e Forma:SolidPeso molecular:329.17VEGFR-2-IN-9
CAS:VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor (IC50: 7 nM). It can be used to study breast cancer.Fórmula:C23H25N3O3Pureza:97.19%Cor e Forma:SolidPeso molecular:391.46Brolucizumab
CAS:Brolucizumab (anti-VEGF-A scFv) potently blocks VEGF-A to reduce neovascularization in wet AMD, with picomolar binding affinity.Pureza:95%Cor e Forma:LiquidPeso molecular:~150 kDaTyrphostin AG1433
CAS:Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Fórmula:C16H14N2O2Pureza:98.47%Cor e Forma:SolidPeso molecular:266.29Ref: TM-T13238
1mg49,00€5mg92,00€10mg152,00€25mg258,00€50mg394,00€100mg587,00€500mg1.215,00€1mL*10mM (DMSO)105,00€VEGFR2-IN-3
CAS:VEGFR2-IN-3 (compound 385) is a potent inhibitor of VEGFR2 [1].Fórmula:C26H28ClN5O4Pureza:98%Cor e Forma:SolidPeso molecular:509.98TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.
Fórmula:C26H27Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:512.43
