PDGFR
Os inibidores do receptor do fator de crescimento derivado de plaquetas (PDGFR) são compostos que bloqueiam a sinalização do PDGFR, um receptor envolvido no crescimento celular, proliferação e angiogênese. O PDGFR desempenha um papel significativo no desenvolvimento dos vasos sanguíneos que alimentam os tumores. Inibir o PDGFR pode, portanto, impedir a angiogênese, tornando esses inibidores valiosos na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de PDGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 130 produtos para "PDGFR".
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Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Fórmula:C27H21N3O3Pureza:99.22%Cor e Forma:SolidPeso molecular:435.47Ref: TM-T35570
1mg66,00€5mg144,00€1mL*10mM (DMSO)157,00€10mg245,00€25mg492,00€50mg710,00€100mg973,00€SU16f
CAS:SU16f, a 3-substituted indolin-2-one, is a selective PDGFRβ inhibitor; IC50: 10 nM (PDGFRβ), 140 nM (PDGFR1), 2.29 μM (PDGFR2), halts GC cell growth.Fórmula:C24H22N2O3Pureza:97.69%Cor e Forma:Red SolidPeso molecular:386.44Tyrphostin AG1433
CAS:Tyrphostin AG1433 (AG1433) is an inhibitor of tyrosine kinases and also a dual inhibitor of PDGFRβ(IC50s = 5.0 μM) and VEGFR-2 (Flk-1/KDR)(IC50s = 9.3 μM).Fórmula:C16H14N2O2Pureza:98.47%Cor e Forma:SolidPeso molecular:266.29TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Fórmula:C26H27Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:512.432-Methyl-3-phenylquinoxaline
CAS:2-Methyl-3-phenylquinoxaline (compound 38) serves as an effective inhibitor of the Platelet-Derived Growth Factor Receptor Tyrosine Kinase (PDGF-RTK), exhibiting significant inhibitory activity against the full-length PDGFR kinase in intact cells (IC50 greater than 100 μM).Fórmula:C15H12N2Cor e Forma:SolidPeso molecular:220.27CMV-423
CAS:CMV-423 is an antiviral agent exhibiting effective in vitro activity against beta-herpesviruses, including Human Cytomegalovirus (HCMV), Human Herpesvirus 6 (HHV-6), and Human Herpesvirus 7 (HHV-7). It is utilized in antiviral research.Fórmula:C14H14ClN3OCor e Forma:SolidPeso molecular:275.73Imatinib Mesylate
CAS:Fórmula:C29H31N7O·CH4O3SPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:589.72GW 2580
CAS:Fórmula:C20H22N4O3Pureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:366.42Nintedanib
CAS:Fórmula:C31H33N5O4Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Yellow to Yellow green powder to crystalPeso molecular:539.64Linifanib
CAS:Fórmula:C21H18FN5OPureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow powder to crystalPeso molecular:375.41
