c-Met/HGFR
Os inibidores de c-Met/HGFR visam o Receptor do Fator de Crescimento de Hepatócitos (c-Met), uma tirosina quinase envolvida em processos celulares como crescimento, motilidade e morfogênese. A sinalização de c-Met está implicada na progressão do câncer, na metástase e na resistência às terapias. Inibir o c-Met pode interromper o crescimento e a disseminação do tumor, tornando esses inibidores valiosos na pesquisa sobre o câncer. Na CymitQuimica, oferecemos inibidores de c-Met/HGFR para apoiar sua pesquisa em oncologia, metástase e terapias contra o câncer.
Foram encontrados 144 produtos de "c-Met/HGFR"
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Boditrectinib
CAS:Boditrectinib: potent TKI, anti-cancer, researches cancer, inflammation, neurodegeneration, infections.Fórmula:C23H24F2N6OCor e Forma:SolidPeso molecular:438.47Glesatinib hydrochloride
CAS:Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO.Fórmula:C31H28ClF2N5O3S2Pureza:98%Cor e Forma:SolidPeso molecular:656.16Vabametkib
CAS:Vabametkib: potent HGFR inhibitor, IC50 = 7 nM, halts Hs746T cell growth, used in cancer therapy.Fórmula:C29H34N12OCor e Forma:SolidPeso molecular:566.66c-Met-IN-16
CAS:c-Met-IN-16 is a c-Met inhibitor that can be used for cancer research .Fórmula:C21H17F2N9OCor e Forma:SolidPeso molecular:449.42Mifanertinib
CAS:Mifanertinib is a potent tyrosine kinase inhibitor with antineoplastic activity .Fórmula:C21H19ClF3N5O2Cor e Forma:SolidPeso molecular:465.86Axl-IN-8
CAS:Axl-IN-8 (NO.1) is a potent inhibitor of AXL (IC50<1 nM) and also inhibits c-MET (IC50: 1-10 nM). : 120.3 nM).Fórmula:C31H29FN6O3Cor e Forma:SolidPeso molecular:552.6c-Met-IN-11
CAS:c-Met-IN-11 is a potent inhibitor of c-MET (IC50: 41.4 nM) and VEGFR-2 (IC50: 71.1 nM).Fórmula:C30H20F2N4O3Cor e Forma:SolidPeso molecular:522.5LCRF-0004
CAS:LCRF-0004 inhibits RON kinase, key in KRAS-driven pancreatic cancer, reducing cell migration and enhancing chemo sensitivity.Fórmula:C28H18F4N6O2SCor e Forma:SolidPeso molecular:578.54AC-386
CAS:AC-386, a potent c-Met inhibitor (IC50 7.42 nM), inhibits cancer cell growth and aids anti-cancer resistance study.Fórmula:C35H34FN5O6Cor e Forma:SolidPeso molecular:639.67SAR125844
CAS:SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)Fórmula:C25H23FN8O2S2Pureza:98.73%Cor e Forma:SolidPeso molecular:550.63Ref: TM-T5467
1mg34,00€5mg74,00€1mL*10mM (DMSO)92,00€10mg110,00€25mg215,00€50mg344,00€100mg557,00€200mg790,00€Mifanertinib dimaleate
CAS:Mifanertinib dimaleate is a potent tyrosine kinase inhibitor with antineoplastic activity .Fórmula:C29H27ClF3N5O10Cor e Forma:SolidPeso molecular:698Tyrosine kinase-IN-4
CAS:Tyrosine kinase-IN-4 (EXAMPLE 107) is a protein tyrosine kinase inhibitor [1].Fórmula:C23H21N3O3Cor e Forma:SolidPeso molecular:387.43Glesatinib
CAS:Glesatinib is an orally active and potent dual inhibitor of MET/SMO.Fórmula:C31H27F2N5O3S2Pureza:98%Cor e Forma:SolidPeso molecular:619.7Terevalefim
CAS:Terevalefim (ANG-3777) is an hepatocyte growth factor (HGF) mimetic. Terevalefim selectively activates the c-Met receptor.Fórmula:C9H8N2SPureza:99.8%Cor e Forma:SolidPeso molecular:176.24Ref: TM-T37596
1mg52,00€5mg113,00€1mL*10mM (DMSO)113,00€10mg200,00€25mg349,00€50mg510,00€100mg712,00€500mg1.459,00€(rel)-Tivantinib
CAS:(rel)-Tivantinib is a potent, highly selective inhibitor of the receptor tyrosine kinase c-MET and has additional novel targets, GSK3α and GSK3β, that areFórmula:C23H19N3O2Cor e Forma:SolidPeso molecular:369.42Tyrosine kinase-IN-6
CAS:Tyrosine kinase-IN-6 is a potent inhibitor of RON splice variants, demonstrating significant anticancer and antineoplastic effects [1].Fórmula:C37H31F2N5O5SPureza:98%Cor e Forma:SolidPeso molecular:695.73SOMG-833 HCl
CAS:SOMG-833 HCl is a selective inhibitor of c-MET. It acts by blocking c-MET dependent neoplastic effects and exerting antitumor activity.Fórmula:C22H22F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:445.44c-met-IN-1
CAS:c-met-IN-1 is a potent and selective c-Met inhibitor (IC50: 1.1 nM) with antitumor activity.Fórmula:C35H37FN6O5Pureza:98%Cor e Forma:SolidPeso molecular:640.7SOMCL-863
CAS:SOMCL-863 is a selective and orally bioavailable c-Met inhibitor. It shows antitumor activity both in vitro and in vivo.
Fórmula:C23H24F3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:475.46(3S,4S)-Tivantinib
CAS:(3S,4S)-Tivantinib, a potent and highly selective inhibitor of the receptor tyrosine kinase c-MET, targets GSK3α and GSK3β—two novel enzymes implicated in theFórmula:C23H19N3O2Cor e Forma:SolidPeso molecular:369.42
