c-Met/HGFR
Os inibidores de c-Met/HGFR visam o Receptor do Fator de Crescimento de Hepatócitos (c-Met), uma tirosina quinase envolvida em processos celulares como crescimento, motilidade e morfogênese. A sinalização de c-Met está implicada na progressão do câncer, na metástase e na resistência às terapias. Inibir o c-Met pode interromper o crescimento e a disseminação do tumor, tornando esses inibidores valiosos na pesquisa sobre o câncer. Na CymitQuimica, oferecemos inibidores de c-Met/HGFR para apoiar sua pesquisa em oncologia, metástase e terapias contra o câncer.
Foram encontrados 128 produtos de "c-Met/HGFR"
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SU11274
CAS:<p>SU11274 (Met Kinase Inhibitor)(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.</p>Fórmula:C28H30ClN5O4SPureza:98.62% - 99.53%Cor e Forma:Orange PowderPeso molecular:568.09AMG-458
CAS:<p>AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.</p>Fórmula:C30H29N5O5Pureza:99.91% - 99.98%Cor e Forma:SolidPeso molecular:539.58Glesatinib
CAS:<p>Glesatinib is an orally active and potent dual inhibitor of MET/SMO.</p>Fórmula:C31H27F2N5O3S2Pureza:98%Cor e Forma:SolidPeso molecular:619.7Dalmelitinib
CAS:<p>Dalmelitinib: oral c-Met kinase inhibitor, IC50 2.9 nM, disrupts MET, AKT, ERK in cancer cells, for NSCLC research.</p>Fórmula:C22H16FN7O2SCor e Forma:SolidPeso molecular:461.47c-Met-IN-16
CAS:<p>c-Met-IN-16 is a c-Met inhibitor that can be used for cancer research .</p>Fórmula:C21H17F2N9OCor e Forma:SolidPeso molecular:449.42ABN401
CAS:<p>ABN401: potent c-MET inhibitor (IC50: 10 nM), cytotoxic to MET-dependent cancers, blocks tumor c-MET phosphorylation, for cancer research.</p>Fórmula:C29H34N12OCor e Forma:SolidPeso molecular:566.66AC-386
CAS:<p>AC-386, a potent c-Met inhibitor (IC50 7.42 nM), inhibits cancer cell growth and aids anti-cancer resistance study.</p>Fórmula:C35H34FN5O6Cor e Forma:SolidPeso molecular:639.67Tyrosine kinase-IN-4
CAS:<p>Tyrosine kinase-IN-4 (EXAMPLE 107) is a protein tyrosine kinase inhibitor [1].</p>Fórmula:C23H21N3O3Cor e Forma:SolidPeso molecular:387.43LCRF-0004
CAS:<p>LCRF-0004 inhibits RON kinase, key in KRAS-driven pancreatic cancer, reducing cell migration and enhancing chemo sensitivity.</p>Fórmula:C28H18F4N6O2SCor e Forma:SolidPeso molecular:578.54c-Met-IN-13
CAS:<p>c-Met-IN-13: potent c-Met inhibitor (IC50 2.43 nM), exhibits anti-proliferative, cytotoxic effects; potential cancer therapy.</p>Fórmula:C30H28F2N2O6Cor e Forma:SolidPeso molecular:550.55SAR125844
CAS:<p>SAR125844, a potent and highly selective inhibitor of the MET receptor tyrosine kinase (RTK), for intravenous administration. (IC50 value of 4.2 nmol/L)</p>Fórmula:C25H23FN8O2S2Pureza:98.73%Cor e Forma:SolidPeso molecular:550.63c-Met-IN-11
CAS:<p>c-Met-IN-11 is a potent inhibitor of c-MET (IC50: 41.4 nM) and VEGFR-2 (IC50: 71.1 nM).</p>Fórmula:C30H20F2N4O3Cor e Forma:SolidPeso molecular:522.5Glesatinib hydrochloride
CAS:<p>Glesatinib hydrochloride is an orally active and potent dual inhibitor of MET/SMO.</p>Fórmula:C31H28ClF2N5O3S2Pureza:98%Cor e Forma:SolidPeso molecular:656.16Axl-IN-8
CAS:<p>Axl-IN-8 (NO.1) is a potent inhibitor of AXL (IC50<1 nM) and also inhibits c-MET (IC50: 1-10 nM). : 120.3 nM).</p>Fórmula:C31H29FN6O3Cor e Forma:SolidPeso molecular:552.6T-1840383
CAS:<p>T-1840383 blocks VEGFR-2 and c-Met phosphorylation in endothelial and cancer cells.</p>Fórmula:C30H25ClFN5O4Cor e Forma:SolidPeso molecular:574MK-8033 hydrochloride
CAS:<p>MK-8033 hydrochloride is an oral ATP-competitive c-Met/Ron inhibitor (IC50: c-Met 1nM, Ron 7nM), used for various cancers including NSCLC.</p>Fórmula:C25H22ClN5O3SCor e Forma:SolidPeso molecular:507.99Mifanertinib dimaleate
CAS:<p>Mifanertinib dimaleate is a potent tyrosine kinase inhibitor with antineoplastic activity .</p>Fórmula:C29H27ClF3N5O10Cor e Forma:SolidPeso molecular:698c-Met-IN-12
CAS:<p>c-Met-IN-12: potent c-Met/AXL/Mer/TYRO3 inhibitor, IC50=10.6 nM, oral, anti-tumor, scaffold for selectivity enhancement.</p>Fórmula:C34H29FN4O4Cor e Forma:SolidPeso molecular:576.62Boditrectinib
CAS:<p>Boditrectinib: potent TKI, anti-cancer, researches cancer, inflammation, neurodegeneration, infections.</p>Fórmula:C23H24F2N6OCor e Forma:SolidPeso molecular:438.47Mifanertinib
CAS:<p>Mifanertinib is a potent tyrosine kinase inhibitor with antineoplastic activity .</p>Fórmula:C21H19ClF3N5O2Cor e Forma:SolidPeso molecular:465.86
