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PYK2

PYK2

Os inibidores de PYK2 são compostos que inibem a quinase de tirosina rica em prolina 2 (PYK2), uma tirosina quinase não receptora envolvida em processos celulares como adesão, migração e sobrevivência. PYK2 está implicada na metástase do câncer e em distúrbios neurológicos. Na CymitQuimica, oferecemos inibidores de PYK2 para apoiar sua pesquisa em metástase do câncer, neurobiologia e sinalização celular.

Foram encontrados 7 produtos de "PYK2"

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  • BT-Amide
    Targetmol
    + Info

    BT-Amide

    BT-Amide is an orally active Pyk2 kinase (Pyk2kinase) inhibitor with an IC50 of 44.69 nM. It prevents glucocorticoid-induced bone loss and demonstrates bone-protective activity in C57BL/6 mice.
    Fórmula:C29H38ClN7O11P2
    Cor e Forma:Solid
    Peso molecular:758.053

    Ref: TM-T204768

    10mg
    A consultar
    50mg
    A consultar
  • PF-562271 besylate
    Targetmol
    + Info

    PF-562271 besylate

    CAS:
    PF-562271 besylate: potent, ATP-competitive FAK inhibitor, IC50 1.5 nM, 10x less effective on Pyk2, highly selective vs other kinases.
    Fórmula:C21H20F3N7O3S·C6H6O3S
    Pureza:97.65% - 99.01%
    Cor e Forma:Solid
    Peso molecular:665.66

    Ref: TM-T6177

    1mg
    35,00€
    5mg
    74,00€
    10mg
    94,00€
    25mg
    138,00€
    50mg
    198,00€
    100mg
    296,00€
    200mg
    427,00€
    1mL*10mM (DMSO)
    89,00€
  • PF-431396
    Targetmol
    + Info

    PF-431396

    CAS:
    PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).
    Fórmula:C22H21F3N6O3S
    Pureza:98.83% - 99.82%
    Cor e Forma:Solid
    Peso molecular:506.5

    Ref: TM-T2314

    5mg
    55,00€
    10mg
    81,00€
    25mg
    145,00€
    50mg
    248,00€
    100mg
    424,00€
    200mg
    627,00€
    1mL*10mM (DMSO)
    65,00€
  • PF-562271 hydrochloride
    Targetmol
    + Info

    PF-562271 hydrochloride

    CAS:
    PF-562271 hydrochloride (PF-562271 HCl) is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK.
    Fórmula:C21H20F3N7O3SHCl
    Pureza:97.08%
    Cor e Forma:Solid
    Peso molecular:543.95

    Ref: TM-T21768

    5mg
    78,00€
    10mg
    97,00€
    25mg
    153,00€
    50mg
    212,00€
    100mg
    314,00€
  • PF-562271
    Targetmol
    + Info

    PF-562271

    CAS:
    PF-562271 is an effective ATP-competitive, reversible inhibitor of FAK(IC50=1.5 nM) and Pyk2 kinase(IC50=13 nM).
    Fórmula:C21H20F3N7O3S
    Pureza:97.17% - >99.99%
    Cor e Forma:Solid
    Peso molecular:507.49

    Ref: TM-T2465

    1mg
    56,00€
    5mg
    120,00€
    10mg
    150,00€
    25mg
    215,00€
    50mg
    358,00€
    100mg
    537,00€
    1mL*10mM (DMSO)
    133,00€
  • NVP-TAE 226
    Targetmol
    + Info

    NVP-TAE 226

    CAS:
    NVP-TAE 226: Potent FAK inhibitor, IC50=5.5nM, stronger vs Pyk2, IC50=3.5nM, weaker against IGF-1R, InsR, c-Met, ALK.
    Fórmula:C23H25ClN6O3
    Pureza:98.07% - 98.78%
    Cor e Forma:Solid
    Peso molecular:468.94

    Ref: TM-T1918

    1mg
    46,00€
    2mg
    59,00€
    5mg
    96,00€
    10mg
    155,00€
    25mg
    250,00€
    50mg
    358,00€
    100mg
    537,00€
    1mL*10mM (DMSO)
    96,00€
  • PF-4618433
    Targetmol
    + Info

    PF-4618433

    CAS:
    PF-4618433 is a selective PYK2 inhibitor with osteogenic activity.
    Fórmula:C24H27N7O2
    Pureza:99.95%
    Cor e Forma:Solid
    Peso molecular:445.52

    Ref: TM-T22397

    2mg
    146,00€