Src
Os inibidores de Src são compostos que têm como alvo as quinases da família Src, que estão envolvidas em vários processos celulares, incluindo crescimento, diferenciação e angiogênese. As quinases Src desempenham um papel crucial nas vias de sinalização que promovem a formação de novos vasos sanguíneos em tumores. Ao inibir Src, é possível interromper essas vias, reduzindo assim a angiogênese e o crescimento tumoral. Os inibidores de Src são amplamente utilizados na pesquisa do câncer e no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de Src de alta qualidade para apoiar sua pesquisa em oncologia, sinalização celular e angiogênese.
Foram encontrados 82 produtos de "Src"
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NVP-BHG 712
CAS:Fórmula:C26H20F3N7OPureza:>95.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:503.49Dasatinib
CAS:Fórmula:C22H26ClN7O2SPureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:488.01Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Fórmula:C22H28ClN7O3SPureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:506.03Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C27H33N3O6SPureza:99%Cor e Forma:SolidPeso molecular:527.63Ref: TM-T15675
2mg35,00€5mg52,00€1mL*10mM (DMSO)62,00€10mg66,00€25mg119,00€50mg230,00€100mg394,00€200mg532,00€Ref: IN-DA00AP0L
1gA consultar1mg27,00€5mg67,00€10mg81,00€25mg110,00€50mg126,00€100mg193,00€250mg273,00€Hck-IN-1
CAS:Hck-IN-1 selectively inhibits Nef:Hck, IC50: 2.8 μM; >20 μM for Hck alone. Potent HIV-1 Nef antagonist, IC50: 100-300 nM for HIV-1 replication.Fórmula:C16H11ClN6O3SPureza:99.07%Cor e Forma:SolidPeso molecular:402.81Ref: TM-T11538
1mg62,00€5mg128,00€1mL*10mM (DMSO)141,00€10mg197,00€25mg323,00€50mg469,00€100mg637,00€Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Cor e Forma:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45Adrenalone hydrochloride
CAS:Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.Fórmula:C9H11NO3·HClPureza:99.94%Cor e Forma:SolidPeso molecular:217.65CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Fórmula:C20H20FN7O2Pureza:99.29%Cor e Forma:SolidPeso molecular:409.42Dasatinib
CAS:Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Cor e Forma:Pale-Yellow SolidPeso molecular:488.01N-Acetyl-O-phosphono-Tyr-Glu Dipentylamide
CAS:Phosphopeptide; binds to the src SH2 domain.Fórmula:C26H42N3O9PPureza:98%Cor e Forma:SolidPeso molecular:571.61Secretin, canine
CAS:Secretin: endocrine hormone, increases bicarbonate-rich pancreatic fluid, regulates canine gastric functions via Src kinase pathway.Fórmula:C131H222N44O41Pureza:98%Cor e Forma:SolidPeso molecular:3069.43Kinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Cor e Forma:Odour SolidRef: TM-L1600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarTyrosine Kinase Inhibitor Library
A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase relatedCor e Forma:Odour SolidRef: TM-L2200
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarAc-Tyr(PO3H2)-Glu-Glu-Ile-Glu-OH
CAS:Phosphopeptide ligand for the src SH2 domain (IC50 = 1 μM). Blocks src interactions with EGFR and FAK.Fórmula:C32H46N5O17PPureza:98%Cor e Forma:SolidPeso molecular:803.71Caffeic acid-pYEEIE
CAS:Phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE,).
Fórmula:C39H50N5O19PPureza:98%Cor e Forma:SolidPeso molecular:923.82Osteogenic Growth Peptide (10-14) acetate
Osteogenic Growth Peptide (10-14) acetate (Osteogenic Growth Peptide) is a Src inhibitor and an effective mitogen and stimulator of osteogenesis andFórmula:C26H33N5O9Pureza:98.69%Cor e Forma:SolidPeso molecular:559.57Ref: TM-T37603L
1mg205,00€2mg358,00€5mg515,00€1mL*10mM (DMSO)695,00€10mg737,00€25mg1.125,00€50mg1.521,00€100mg2.052,00€LCB 03-0110 dihydrochloride
CAS:LCB 03-0110 Dihydrochloride is a potent inhibitor of the c-Src kinase (IC50 = 1.3 nM) and tyrosine kinases in the BTK and SYK family, as well as in the DDR2Fórmula:C24H25Cl2N3O2SPureza:99.9%Cor e Forma:SoildPeso molecular:490.45Ref: TM-T32613
100mgA consultar1mg73,00€2mg99,00€5mg152,00€1mL*10mM (DMSO)178,00€10mg215,00€25mg358,00€50mg512,00€Hck-IN-2
Hck-IN-2 (Compound 8e) acts as an HCK inhibitor with demonstrated cytotoxic effects on tumor cells. It exhibits an IC50 of 19.58 μM for MDA-MB231 cells and 1.42 μM for MCF-7 cells. Additionally, Hck-IN-2 possesses antitumor activity.Fórmula:C36H35FN6O10Cor e Forma:SolidPeso molecular:730.696pYEEI
pYEEI, a tetrapeptide containing phosphotyrosine, binds to the SrcSH2 domain with a dissociation constant (Kd) of 100 nM and an inhibitory concentration (IC50) of 6.5 μM. This compound plays a crucial role in cancer research.Fórmula:C25H36N3O14PCor e Forma:SolidPeso molecular:633.54AP23846
CAS:AP23846 is an Src family kinase inhibitor that reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines.Fórmula:C24H34N5OPPureza:97.83%Cor e Forma:SolidPeso molecular:439.531-Naphthyl PP1
CAS:Fórmula:C19H19N5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:317.40PP 2
CAS:Fórmula:C15H16ClN5Pureza:>97.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:301.78Anti-Src Antibody (1E789)
Anti-Src Antibody (1E789) is an antibody targeting Src. Anti-Src Antibody (1E789) can be used in ELISA, WB, IF, FCM.Cor e Forma:Odour LiquidPP 1
CAS:Fórmula:C16H19N5Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:281.36WHI-P154
CAS:Fórmula:C16H14BrN3O3Pureza:>98.0%(HPLC)Cor e Forma:White to Yellow to Orange powder to crystalPeso molecular:376.21A-770041
CAS:A-770041 is an Lck inhibitor, YZ inhibits the production of IL-2 stimulated by concanavalin A in whole blood, and can prevent cardiac allograft rejection.Fórmula:C34H39N9O3Pureza:99.23% - 99.86%Cor e Forma:SolidPeso molecular:621.73Ref: TM-T14074
2mg70,00€5mg104,00€1mL*10mM (DMSO)142,00€10mg170,00€25mg384,00€50mg652,00€100mg1.018,00€200mg1.350,00€Saracatinib
CAS:Fórmula:C27H32ClN5O5Pureza:>95.0%(HPLC)(qNMR)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:542.03Bosutinib
CAS:Fórmula:C26H29Cl2N5O3Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:530.45Pelitinib
CAS:Pelitinib (EKB-569) (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).Fórmula:C24H23ClFN5O2Pureza:98.37% - 99.84%Cor e Forma:Off-White SolidPeso molecular:467.92RK-24466
CAS:RK-24466 (KIN 001-51) is a selective and potent inhibitor of Lck, inhibits Lck (64-509) and LckCD isoforms with IC50s of less than 1 and 2 nM, respectively.Fórmula:C23H22N4OPureza:98.07%Cor e Forma:SolidPeso molecular:370.45Ref: TM-T16760
1mg63,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg215,00€25mg371,00€50mg557,00€100mg858,00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:97.58% - 99.94%Cor e Forma:SolidPeso molecular:419.48Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Fórmula:C28H30N6OSPureza:97.56% - >99.99%Cor e Forma:SolidPeso molecular:498.64SU6656
CAS:SU 6656 is a selective inhibitor of Src family kinases, with IC50 of 280 nM, 20 nM, 130 nM, and 170 nM for Src, Yes, Lyn, and Fyn, respectively.Fórmula:C19H21N3O3SPureza:98.21% - 98.73%Cor e Forma:SolidPeso molecular:371.45PP2
CAS:PP2 (AG 1879,AGL 1879) is a effective inhibitor of Lck/Fyn (IC50:4/5 nM) , ~100-fold less potent to EGFR, inactive for ZAP-70, PKA and JAK2.Fórmula:C15H16ClN5Pureza:98% - 98.21%Cor e Forma:White SolidPeso molecular:301.77Ref: TM-T6266
2mg44,00€5mg65,00€1mL*10mM (DMSO)71,00€10mg110,00€25mg178,00€50mg304,00€100mg482,00€200mg687,00€PD-161570
CAS:PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM.Fórmula:C26H35Cl2N7OPureza:99.92%Cor e Forma:SolidPeso molecular:532.51Ref: TM-T23127
1mg34,00€5mg96,00€1mL*10mM (DMSO)118,00€10mg141,00€25mg289,00€50mg465,00€100mg662,00€200mg888,00€β-Hydroxyisovalerylshikonin
CAS:Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumorFórmula:C21H24O7Pureza:98.16%Cor e Forma:SolidPeso molecular:388.41Pyridostatin TFA
CAS:Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Cor e Forma:SolidPeso molecular:938.71Pyridostatin
CAS:Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome orFórmula:C31H32N8O5Pureza:98%Cor e Forma:SolidPeso molecular:596.64AD80
CAS:AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Fórmula:C22H19F4N7OPureza:99.49% - 99.75%Cor e Forma:SolidPeso molecular:473.43Ref: TM-T4301
1mg44,00€1mL*10mM (DMSO)90,00€5mg96,00€10mg138,00€25mg268,00€50mg439,00€100mg645,00€500mg1.333,00€Tolimidone
CAS:Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.Fórmula:C11H10N2O2Pureza:99.85% - 99.85%Cor e Forma:SolidPeso molecular:202.21eCF506
CAS:eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Fórmula:C26H38N8O3Pureza:97.85% - 98.16%Cor e Forma:SolidPeso molecular:510.63Rebastinib
CAS:DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,
Fórmula:C30H28FN7O3Pureza:99.53% - 99.79%Cor e Forma:SolidPeso molecular:553.59UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.Fórmula:C30H31F3N8O3SPureza:98.72% - 99.52%Cor e Forma:SolidPeso molecular:640.68Saracatinib
CAS:Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Fórmula:C27H32ClN5O5Pureza:98% - 99.63%Cor e Forma:SolidPeso molecular:542.031-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Fórmula:C19H19N5Pureza:99.85%Cor e Forma:White Cyrstalline SolidPeso molecular:317.39Src Inhibitor 1
CAS:Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.Fórmula:C22H19N3O3Pureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:373.4Ref: TM-T3593
1mL*10mM (DMSO)A consultar2mg38,00€5mg56,00€10mg94,00€25mg172,00€50mg268,00€100mg429,00€200mg615,00€Ponatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFórmula:C29H27F3N6OPureza:98% - 99.60%Cor e Forma:SolidPeso molecular:532.56PI3K-IN-1
CAS:PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.Fórmula:C31H29N5O6SPureza:97.03% - 98%Cor e Forma:SolidPeso molecular:599.66
