Src
Os inibidores de Src são compostos que têm como alvo as quinases da família Src, que estão envolvidas em vários processos celulares, incluindo crescimento, diferenciação e angiogênese. As quinases Src desempenham um papel crucial nas vias de sinalização que promovem a formação de novos vasos sanguíneos em tumores. Ao inibir Src, é possível interromper essas vias, reduzindo assim a angiogênese e o crescimento tumoral. Os inibidores de Src são amplamente utilizados na pesquisa do câncer e no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de Src de alta qualidade para apoiar sua pesquisa em oncologia, sinalização celular e angiogênese.
Foram encontrados 82 produtos de "Src"
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AD80
CAS:AD80, a multikinase inhibitor, inhibits RET, RAF, SRCand S6K, with greatly reduced mTOR activity.Fórmula:C22H19F4N7OPureza:99.49% - 99.75%Cor e Forma:SolidPeso molecular:473.43Ref: TM-T4301
1mg44,00€5mg96,00€10mg138,00€25mg268,00€50mg439,00€100mg645,00€500mg1.333,00€1mL*10mM (DMSO)90,00€Tolimidone
CAS:Tolimidone (NSC 314335) is a chemical compound which inhibits acid secretion in animal models and also acts as a bronchodilator in histamine-challenged animals.
Fórmula:C11H10N2O2Pureza:99.85% - 99.85%Cor e Forma:SolidPeso molecular:202.21eCF506
CAS:eCF506 is a potent and selective inhibitor of SRC (IC50 < 0.5 nM)Fórmula:C26H38N8O3Pureza:97.85% - 98.16%Cor e Forma:SolidPeso molecular:510.63Rebastinib
CAS:DCC-2036 (Rebastinib (DCC-2036)) is a conformational control Bcr-Abl inhibitor for Abl1(WT, IC50: 0.8 nM) and Abl1(T315I, IC50: 4 nM), also inhibits LYN, SRC,
Fórmula:C30H28FN7O3Pureza:99.53% - 99.79%Cor e Forma:SolidPeso molecular:553.59UM-164
CAS:UM-164 (DAS-DFGO-II), a highly potent c-Src inhibitor with a dissociation constant (Kd) of 2.7 nM, also effectively inhibits p38α and p38β.
Fórmula:C30H31F3N8O3SPureza:98.72% - 99.52%Cor e Forma:SolidPeso molecular:640.68Saracatinib
CAS:Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.Fórmula:C27H32ClN5O5Pureza:98% - 99.63%Cor e Forma:SolidPeso molecular:542.031-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Fórmula:C19H19N5Pureza:99.85%Cor e Forma:White Cyrstalline SolidPeso molecular:317.39Src Inhibitor 1
CAS:Src Inhibitor 1 (Src Kinase Inhibitor 1) is a potent and selective dual site Src tyrosine kinase inhibitor.Fórmula:C22H19N3O3Pureza:99.68% - >99.99%Cor e Forma:SolidPeso molecular:373.4Ref: TM-T3593
2mg38,00€5mg56,00€10mg94,00€25mg172,00€50mg268,00€100mg429,00€200mg615,00€1mL*10mM (DMSO)A consultarPonatinib
CAS:Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectivelyFórmula:C29H27F3N6OPureza:98% - 99.60%Cor e Forma:SolidPeso molecular:532.56PI3K-IN-1
CAS:PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.Fórmula:C31H29N5O6SPureza:97.03% - 98%Cor e Forma:SolidPeso molecular:599.66MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Cor e Forma:Yellow PowderPeso molecular:193.16lavendustin C
CAS:lavendustin C (NSC 666251) is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase.Fórmula:C14H13NO5Pureza:98.06%Cor e Forma:Yellow To Tan PowderPeso molecular:275.26Ref: TM-T4185
1mg42,00€2mg55,00€5mg93,00€10mg152,00€25mg330,00€50mg492,00€100mg707,00€1mL*10mM (DMSO)90,00€PP1
CAS:PP1 (AGL 1872), a specific and effective Src inhibitor, is with IC50 for Lck/Fyn is 5 nM/ 6 nM, respectively.Fórmula:C16H19N5Pureza:99% - 99.88%Cor e Forma:Off-White To Grey SolidPeso molecular:281.36Ref: TM-T6196
1mg38,00€2mg50,00€5mg84,00€10mg112,00€25mg190,00€50mg268,00€100mg421,00€500mg945,00€1mL*10mM (DMSO)89,00€WH-4-023
CAS:WH-4-023 (Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor. It also potently inhibits SIK.Fórmula:C32H36N6O4Pureza:98% - 99.75%Cor e Forma:SolidPeso molecular:568.67Ref: TM-T1811
2mg51,00€5mg74,00€10mg99,00€25mg162,00€50mg197,00€100mg350,00€1mL*10mM (DMSO)A consultar1-NM-PP1
CAS:1-NM-PP1 (PP1 Analog II) is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.Fórmula:C20H21N5Pureza:98% - 98.93%Cor e Forma:White Cyrstalline SolidPeso molecular:331.41Ref: TM-T2153
1mg48,00€2mg63,00€5mg84,00€10mg132,00€25mg271,00€50mg505,00€100mg668,00€1mL*10mM (DMSO)90,00€Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Cor e Forma:SolidPeso molecular:594.75KX1-004
CAS:KX1-004, a potential protective drug for NIHL, is an effective small molecule inhibitor of Src-PTK.Fórmula:C16H13FN2O2Pureza:99.39% - ≥95%Cor e Forma:SolidPeso molecular:284.29Ref: TM-T1812
1mg43,00€2mg56,00€5mg93,00€10mg152,00€25mg268,00€50mg442,00€100mg622,00€500mg1.305,00€1mL*10mM (DMSO)92,00€squarunkinA
CAS:squarunkinA is a novel modulator of the UNC119-Cargo Interaction, potently and selectively inhibiting the binding of a myristoylated peptide representing the N-Fórmula:C25H32F3N5O4Pureza:99.29%Cor e Forma:SolidPeso molecular:523.55PP121
CAS:PP-121 inhibits PDGFR, Hck, mTOR, VEGFR2, Src, Abl, and DNA-PK with IC50 values ranging from 2 to 60 nM.Fórmula:C17H17N7Pureza:98.45% - 99.93%Cor e Forma:SolidPeso molecular:319.36Scutellarein
CAS:Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.Fórmula:C15H10O6Pureza:98.02% - 99.63%Cor e Forma:SolidPeso molecular:286.24Ref: TM-T3319
2mg38,00€5mg52,00€10mg75,00€25mg109,00€50mg159,00€100mg227,00€200mg338,00€1mL*10mM (DMSO)59,00€
