Src
Os inibidores de Src são compostos que têm como alvo as quinases da família Src, que estão envolvidas em vários processos celulares, incluindo crescimento, diferenciação e angiogênese. As quinases Src desempenham um papel crucial nas vias de sinalização que promovem a formação de novos vasos sanguíneos em tumores. Ao inibir Src, é possível interromper essas vias, reduzindo assim a angiogênese e o crescimento tumoral. Os inibidores de Src são amplamente utilizados na pesquisa do câncer e no desenvolvimento terapêutico. Na CymitQuimica, oferecemos uma seleção abrangente de inibidores de Src de alta qualidade para apoiar sua pesquisa em oncologia, sinalização celular e angiogênese.
Foram encontrados 82 produtos de "Src"
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1-Naphthyl PP1 hydrochloride
CAS:1-Naphthyl PP1 hydrochloride (1-NA-PP 1 hydrochloride) is a selective inhibitor of src family kinases v-SrcFórmula:C19H20ClN5Pureza:98.63%Cor e Forma:SolidPeso molecular:353.85Periplocin
CAS:Periplocin fights lung cancer, induces apoptosis, stunts growth via beta-catenin/Tcf, and treats rheumatoid arthritis/traditional ailments.Fórmula:C36H56O13Pureza:99.66% - 99.74%Cor e Forma:SolidPeso molecular:696.82Ref: TM-T5S1982
1mg35,00€5mg77,00€10mg106,00€25mg170,00€50mg253,00€100mg375,00€500mg892,00€1mL*10mM (DMSO)107,00€Tetramethylcurcumin
CAS:Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it alsoFórmula:C25H28O6Pureza:97.69% - 99.94%Cor e Forma:SolidPeso molecular:424.49Bafetinib
CAS:Bafetinib (INNO-406): Dual Bcr-Abl/Lyn inhibitor; IC50: 5.8/19 nM; ineffective against T315I mutant, less on c-Kit/PDGFR.Fórmula:C30H31F3N8OPureza:94.16% - 99.68%Cor e Forma:SolidPeso molecular:576.62Ref: TM-T6311
1mg34,00€2mg49,00€5mg74,00€10mg98,00€25mg150,00€50mg178,00€100mg333,00€200mg432,00€1mL*10mM (DMSO)95,00€7-Hydroxy-4H-chromen-4-one
CAS:7-Hydroxy-4H-chromen-4-one (7-hydroxy-4-benzopyrone) is a Src kinase inhibitor (IC50 of <300 μM).Fórmula:C9H6O3Pureza:97.65%Cor e Forma:SolidPeso molecular:162.14XL228
CAS:XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).Fórmula:C22H31N9OPureza:99.07%Cor e Forma:SolidPeso molecular:437.54Ref: TM-T17267
1mg52,00€2mg73,00€5mg94,00€10mg141,00€25mg244,00€50mg371,00€100mg552,00€1mL*10mM (DMSO)104,00€Tirbanibulin
CAS:Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.Fórmula:C26H29N3O3Pureza:99.43% - 99.67%Cor e Forma:SolidPeso molecular:431.53Ref: TM-T6345
1mg34,00€5mg60,00€10mg73,00€25mg142,00€50mg253,00€100mg424,00€200mg605,00€1mL*10mM (DMSO)63,00€ENMD-2076
CAS:ENMD-2076, a multi-targeted kinase inhibitor, has specific activity against Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα.Fórmula:C21H25N7Pureza:97.63% - ≥95%Cor e Forma:SolidPeso molecular:375.47PD-089828
CAS:PD 089828 inhibits FGFR1, PDGFRβ, EGFR (IC50s: 0.15-5.47 μM), and c-Src (IC50: 0.18 μM).Fórmula:C18H18Cl2N6OPureza:97.39%Cor e Forma:SolidPeso molecular:405.28PD173955
CAS:PD173955 is src family-selective tyrosine kinase inhibitor with IC50 of ~22 nM for Src, Yes and Abl kinase; less potent for FGFRα and no activity on InsR andFórmula:C21H16Cl2N4OSPureza:98.52% - 98.99%Cor e Forma:SolidPeso molecular:443.35Ref: TM-T3063
2mg35,00€5mg50,00€10mg92,00€25mg166,00€50mg248,00€100mg371,00€200mg530,00€1mL*10mM (DMSO)94,00€AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Fórmula:C29H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:535.56OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Fórmula:C18H15N3O3SPureza:98%Cor e Forma:Dark Orange SolidPeso molecular:353.39TC-S 7003
CAS:TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.Fórmula:C31H30N8OPureza:99.74%Cor e Forma:SolidPeso molecular:530.62A 419259 trihydrochloride
CAS:A 419259 trihydrochloride (RK 20449 trihydrochloride) is an Src family kinases inhibitor (IC50s: 9 nM, 3 nM and 3 nM for Src, Lck and Lyn).Fórmula:C29H37Cl3N6OPureza:99.75% - 99.96%Cor e Forma:SolidPeso molecular:592BT424
CAS:BT424, a specific HCK inhibitor, modulates macrophage activation and autophagy in vitro, and mitigates inflammation and renal fibrosis in the UUO model [1].Fórmula:C22H15BCl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:421.08TL02-59
CAS:TL02-59: Fgr inhibitor (IC50=0.03nM), also targets Lyn (0.1nM), Hck (160nM), halts acute myelogenous leukemia growth.Fórmula:C32H34F3N5O4Pureza:98.77%Cor e Forma:SolidPeso molecular:609.64Ref: TM-T13186
1mg49,00€2mg62,00€5mg93,00€10mg133,00€25mg260,00€50mg401,00€100mg557,00€200mg790,00€1mL*10mM (DMSO)111,00€KB SRC 4
CAS:KB SRC 4 is a selective and potent c-Src inhibitor with antitumour activity that inhibits the growth of cancer cells.CAS 번호13460-73-83-4Fórmula:C32H23ClN8Pureza:98.83% - 99.34%Cor e Forma:SolidPeso molecular:555.03TG 100572 Hydrochloride
CAS:TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.Fórmula:C26H27Cl2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:512.43CH6953755
CAS:CH6953755: oral YES1 kinase inhibitor, IC50 1.8 nM, potent, selective, anticancer, halts cell proliferation.Fórmula:C26H22F2N6O4SPureza:98.87%Cor e Forma:SolidPeso molecular:552.55Ref: TM-T10784
1mg55,00€5mg116,00€10mg177,00€25mg348,00€50mg557,00€100mg893,00€1mL*10mM (DMSO)141,00€Src Inhibitor 3
CAS:Src Inhibitor 3 blocks c-Src kinase (IC50 <3 nM CSK HTRF, <4 nM Caliper), boosting T cell growth from receptor signals.Fórmula:C34H32ClFN8O4Pureza:98.35%Cor e Forma:SolidPeso molecular:671.12Ref: TM-T13000
1mg96,00€5mg177,00€10mg304,00€25mg480,00€50mg665,00€100mgA consultar1mL*10mM (DMSO)264,00€
