Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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Norswertianin
CAS:<p>Norswertianin, a xanthone, induces GBM cell differentiation and autophagy via oxidative stress and Akt/mTOR.</p>Fórmula:C13H8O6Cor e Forma:SolidPeso molecular:260.2ICT5040
CAS:<p>ICT5040 is a CXCR4 antagonist.</p>Fórmula:C10H8F3N3OSCor e Forma:SolidPeso molecular:275.25SB-332235
CAS:<p>SB-332235 is an effective specific CXCR2 antagonist. And it is effectively inhibited CS-induced neutrophilia in a dose-dependent manner.</p>Fórmula:C13H10Cl3N3O4SCor e Forma:SolidPeso molecular:410.66Autophagy-IN-C1
CAS:<p>Autophagy-IN-C1 is a cinchona alkaloid derivative containing urea.</p>Fórmula:C29H28F6N4O2Cor e Forma:SolidPeso molecular:578.55Olacaftor
CAS:<p>Olacaftor, also known as VX-440, is a protein modulator of cystic fibrosis transmembrane regulator (CFTR).</p>Fórmula:C29H34FN3O4SCor e Forma:SolidPeso molecular:539.66PF 750
CAS:<p>PF 750 (ZINC27647189) is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.</p>Fórmula:C22H23N3OPureza:99.87%Cor e Forma:SolidPeso molecular:345.44AMD 3465
CAS:<p>AMD 3465 (GENZ-644494) blocks CXCR4, hinders X4 HIV replication (IC50: 1-10 nM), ineffective against R5 viruses, IC50: 0.75 nM (12G5 mAb), 18 nM (CXCL12AF647).</p>Fórmula:C24H38N6Pureza:98%Cor e Forma:SolidPeso molecular:410.60VUF11211
CAS:<p>VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains.</p>Fórmula:C26H35Cl2N5OPureza:98%Cor e Forma:SolidPeso molecular:504.49AUTEN-67
CAS:<p>AUTEN-67 inhibits MTMR14, boosts autophagy, has antiaging/neuroprotective properties, and combats Huntington's disease onset/severity.</p>Fórmula:C23H14N4O6SCor e Forma:SolidPeso molecular:474.45LV-320
CAS:<p>LV-320, potent ATG4B inhibitor; IC50: 24.5 μM, Kd: 16 μM. Blocks autophagy, stable, non-toxic, active in vivo. Useful for ATG4B research in cancer.</p>Fórmula:C29H26ClNO2S2Pureza:98%Cor e Forma:SolidPeso molecular:520.11Antiproliferative agent-5
CAS:<p>Compound 4o inhibits gastric cancer growth, blocks G2/M cell cycle, induces ROS, and triggers autophagy. Used in anti-cancer studies.</p>Fórmula:C28H21BrN8OSCor e Forma:SolidPeso molecular:597.49CXCR4 antagonist 9
CAS:<p>CXCR4 antagonist 9, with IC50s of 15 nM & 1.3 nM against CXCR4 & Ca²⁺ rise by CXCL12 respectively.</p>Fórmula:C21H27FN6Cor e Forma:SolidPeso molecular:382.48SA 47
CAS:<p>SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.</p>Fórmula:C17H26N4O3Pureza:98%Cor e Forma:SolidPeso molecular:334.41CXCR4 antagonist 8
CAS:<p>CXCR4 antagonist 8 (Compound 3) blocks CXCR4, IC50 of 57 nM; stops CXCL12-induced Ca2+ increase, IC50 of 0.24 nM; hinders cell migration.</p>Fórmula:C21H26N6Cor e Forma:SolidPeso molecular:362.47ALLO-1
CAS:<p>ALLO-1, vital for autophagy, aids in engulfing paternal organelles by binding to worm LC3, LGG-1, via its LIR motif.</p>Fórmula:C17H15ClN2O2Pureza:98%Cor e Forma:SolidPeso molecular:314.77Obatoclax
CAS:<p>Obatoclax (GX15-070), a pan-BCL-2 inhibitor (Ki 220 nM) induces autophagy, degrades cyclin D1, and has anti-cancer/antiparasitic properties.</p>Fórmula:C20H19N3OPureza:99.44%Cor e Forma:SolidPeso molecular:317.38Nicodicosapent
CAS:<p>Nicodicosapent is a fatty acid niacin conjugate that inhibits SREBP, a regulator of cholesterol metabolism.</p>Fórmula:C28H39N3O2Pureza:98%Cor e Forma:SolidPeso molecular:449.63STK683963
CAS:<p>STK683963 activates ATG4B, mediates redox regulation, and aids cancer research.</p>Fórmula:C12H8FN3O2SCor e Forma:SolidPeso molecular:277.27LS2265
CAS:<p>LS2265, a fenofibrate derivative with a taurine modification, effectively induces the proliferation of peroxisomes in rat liver cells.</p>Fórmula:C19H20ClNO6SPureza:98%Cor e Forma:SolidPeso molecular:425.88AGN 205327
CAS:<p>AGN 205327 is a potent synthetic RAR agonist,showing selective RAR activation without RXR inhibition for retinoid research.</p>Fórmula:C24H26N2O3Pureza:99.45% - 99.71%Cor e Forma:SolidPeso molecular:390.47HF51116
CAS:<p>HF51116 blocks XCR4, hinders SDF-1α cell effects & HIV-1; potential for HIV, stem cells, cancer spread.</p>Fórmula:C29H46N8OCor e Forma:SolidPeso molecular:522.73CC214-2
CAS:<p>CC214-2: strong dual mTORC1/2 inhibitor, blocks autophagy, may shorten TB duration.</p>Fórmula:C20H25N5O3Cor e Forma:SolidPeso molecular:383.44AS1708727
CAS:<p>AS1708727 inhibits Foxo1, reducing blood sugar and triglycerides by altering gene expression.</p>Fórmula:C24H24Cl2N2O2Cor e Forma:SolidPeso molecular:443.37Aliskiren fumarate
CAS:<p>Oral renin inhibitor Aliskiren fumarate treats hypertension; IC50: 1.5 nM. Useful for cardiovascular and cancer cachexia research.</p>Fórmula:C34H57N3O10Cor e Forma:SolidPeso molecular:667.83Rimacalib
CAS:<p>Rimacalib is an inhibitor of Ca2+/calmodulin-dependent protein kinase II (IC50s: ~1 μM for CaMKIIα and ~30 μM for CaMKIIγ).</p>Fórmula:C22H23FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:394.44Elliptinium acetate
CAS:<p>Elliptinium acetate (NSC 264137), a cytotoxic DNA intercalator for cancer research, targets L1210 cells.</p>Fórmula:C20H20N2O3Cor e Forma:SolidPeso molecular:336.38SA72
CAS:<p>SA72 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH).</p>Fórmula:C21H26N2O6Pureza:98%Cor e Forma:SolidPeso molecular:402.44SX-517
CAS:<p>SX-517 is a non-competitive dual antagonist of CXCR1/2, demonstrating anti-inflammatory effects, inhibits CXCL-1-induced Ca²⁺ flux.</p>Fórmula:C19H16BFN2O3SCor e Forma:SolidPeso molecular:382.22TN-14003
CAS:<p>TN-14003 is a synthetic antagonist 14-mer peptide inhibiting metastasis in an animal model.</p>Fórmula:C90H141N33O18S2Cor e Forma:SolidPeso molecular:2037.42RNF5 inhibitor inh-02
CAS:<p>RNF5 inhibitor inh-02 is a selective inhibitor of the ubiquitin ligase RNF5/RMA1, which can significantly rescue F508del-CFTR cystic fibrosis (CF).</p>Fórmula:C23H20N4SPureza:99.23%Cor e Forma:SolidPeso molecular:384.5(S)-Hydroxychloroquine
CAS:<p>(S)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine shows efficiently inhibits SARS-CoV-2 infection in vitro.</p>Fórmula:C18H26ClN3OPureza:98%Cor e Forma:SolidPeso molecular:335.87IZCZ-3
CAS:<p>IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.</p>Fórmula:C46H49N7OPureza:98%Cor e Forma:SolidPeso molecular:715.93KRH-1636
CAS:<p>KRH-1636: potent, selective CXCR4 antagonist; orally active; inhibits X4 HIV-1 by blocking viral entry and membrane fusion.</p>Fórmula:C32H37N7O2Cor e Forma:SolidPeso molecular:551.68Autophagy inducer 4
CAS:<p>Autophagy inducer 4, a Magnolol-based Mannich derivative, is an anticancer agent that blocks cancer cell migration & is 76x more toxic to T47D cells.</p>Fórmula:C32H37NO6Cor e Forma:SolidPeso molecular:531.64PX20606 trans racemate
CAS:<p>PX20606 trans racemate is an agonist of FXR (EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively).</p>Fórmula:C29H22Cl3NO4Pureza:98%Cor e Forma:SolidPeso molecular:554.85Antitumor agent-81
CAS:<p>Antitumor agent-81, a P62-RNF168 agonist, reduces H2A ubiquitination, hinders DNA repair, and inhibits tumor growth.</p>Fórmula:C19H19N7O3Cor e Forma:SolidPeso molecular:393.4MPM-1
<p>MPM-1, a marine mimic, induces rapid necrotic-like death in cancer cells, disrupts autophagy, and causes lysosomal swelling.</p>Fórmula:C34H44F6N4O7Cor e Forma:SolidPeso molecular:734.73IT1t
CAS:<p>IT1t inhibits CXCL12/CXCR4 interaction with an IC50 of 2.1 nM. is a potent CXCR4 antagonist.</p>Fórmula:C21H34N4S2Pureza:98%Cor e Forma:SolidPeso molecular:406.65Amsacrine
CAS:<p>Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells.</p>Fórmula:C21H19N3O3SPureza:99.2%Cor e Forma:Yellow Crystalline Powder SolidPeso molecular:393.46CUR5g
CAS:<p>CUR5g is an autophagy inhibitor that inhibits migration and colony formation in A549 cells.</p>Fórmula:C22H20N2O2Pureza:98.92%Cor e Forma:SolidPeso molecular:344.41Evogliptin
CAS:<p>Evogliptin (DA-1229) is an oral DPP4 inhibitor effective in reducing blood sugar and liver inflammation.</p>Fórmula:C19H26F3N3O3Cor e Forma:SolidPeso molecular:401.42ATG7-IN-3
CAS:<p>ATG7-IN-3, or compound 18, is an ATG7 inhibitor with a 0.048 μM IC50, blocking autophagy and LC3B puncta in H4 cells.</p>Fórmula:C11H16N6O5S2Pureza:99.88%Cor e Forma:SolidPeso molecular:376.41Xantocillin
CAS:<p>Xanthocillin is a marine agent. Xanthocillin also induces autophagy through inhibition of the MEK/ERK pathway.</p>Fórmula:C18H12N2O2Pureza:98%Cor e Forma:SolidPeso molecular:288.3YM-155 hydrochloride
CAS:<p>Sepantronium hydrochloride (YM-155 hydrochloride) is a novel survivin suppressant that inhibits survivin promoter with an IC 50 of 0.54 nM[1].</p>Fórmula:C20H19ClN4O3Cor e Forma:SolidPeso molecular:398.85OSU-53
CAS:<p>OSU-53 is an AMPK activator, inhibiting mTOR signaling and autophagy stimulation. OSU-53 also activates mutations in RAS or BRAF.</p>Fórmula:C25H24F3N3O6S2Cor e Forma:SolidPeso molecular:583.6CCT128930
CAS:<p>'CCT128930, potent Akt2 inhibitor (IC50=6 nM), 28x more selective over PKA.'</p>Fórmula:C18H20ClN5Pureza:99.07% - 99.18%Cor e Forma:SolidPeso molecular:341.84FAAH inhibitor 1
CAS:<p>FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.</p>Fórmula:C24H23N3O3S3Pureza:99.6%Cor e Forma:SolidPeso molecular:497.65(Rac)-BL-918
CAS:<p>(Rac)-BL-918 is the racemic form of BL-918. BL-918 is an effective activator of UNC-51-like kinase 1 (ULK1) (EC₅₀ = 24.14 nM), Parkinson's disease.</p>Fórmula:C23H15F8N3OSPureza:98%Cor e Forma:SolidPeso molecular:533.44YOK-2204
CAS:<p>YOK-2204 is a ligand for the p62-ZZ domain and activates p62-dependent selective autophagy. It is also applicable in the design of AUTOTACs.</p>Fórmula:C28H35NO4Cor e Forma:SolidPeso molecular:449.58MRT-68601 HCl
CAS:<p>MRT-68601 HCl, a potent TBK1 (TANK-binding kinase-1), inhibits the formation of autophagosomes in lung cancer cells.</p>Fórmula:C25H34N6O2Pureza:98%Cor e Forma:SolidPeso molecular:450.58FKBP51F67V-selective antagonist Ligand2
CAS:<p>FKBP51F67V-selective antagonist Ligand2 (example 3-3), a potent ligand, selectively binds to the FKBP51 F67V variant, with no affinity for wild-type FKBP51 or</p>Fórmula:C43H56N2O10Pureza:98%Cor e Forma:SolidPeso molecular:760.91TUN-92046
CAS:<p>TUN-92046 is a permeable alpha-ketoglutarate analog that blocks harmful autophagy in cardiomyopathy.</p>Fórmula:C7H10O5Pureza:95.48% - 98.58%Cor e Forma:SolidPeso molecular:174.15Glaucocalyxin B
CAS:<p>Glaucocalyxin B is a diterpenoid isolated from Rabdosia japonica with anticancer and antitumor activity. It decreases the growth of HL-60 cells (IC50: 5.86 μM).</p>Fórmula:C22H30O5Pureza:99.13% - 99.35%Cor e Forma:SolidPeso molecular:374.47GPR35 agonist 1
CAS:<p>GPR35 agonist 1 is a highly effective and specific GPR35/CXCR8 agonist (EC50: 5.8 nM).</p>Fórmula:C10H4BrN5O5Pureza:98%Cor e Forma:SolidPeso molecular:354.07VUF5834
CAS:<p>VUF5834 is a full inverse agonist of CXCR3 N3.35A.</p>Fórmula:C31H41N5O2Pureza:98%Cor e Forma:SolidPeso molecular:515.69LRRK2-IN-10
CAS:<p>LRRK2-IN-10 (compound 34) is a potent, mutation-selective, brain-penetrant inhibitor targeting G2019S-LRRK2 kinase with IC50 values of 11 nM for G2019S-LRRK2</p>Fórmula:C20H15N5OPureza:98%Cor e Forma:SolidPeso molecular:341.37PS372424
CAS:<p>PS372424 is a specific agonist of human CXCR3, with anti-inflammatory activity.</p>Fórmula:C33H44N6O4Pureza:98%Cor e Forma:SolidPeso molecular:588.74AZ10397767
CAS:<p>AZ10397767: Potent CXCR2 blocker (IC50=1nM); lowers neutrophil infiltration in tumors in vitro/in vivo.</p>Fórmula:C15H14ClFN4O2S2Cor e Forma:SolidPeso molecular:400.88FR 167653 free base
CAS:<p>FR 167653 is an oral p38 MAPK inhibitor for inflammation, trauma, ischemia relief; it suppresses TNF-α, IL-1β.</p>Fórmula:C24H18FN5O2Pureza:98%Cor e Forma:SolidPeso molecular:427.43ROC-325
CAS:<p>ROC-325: orally active autophagy inhibitor with anticancer effects, induces kidney cancer cell death; selective action.</p>Fórmula:C28H27ClN4OSPureza:99.26%Cor e Forma:SolidPeso molecular:503.06Sulfosuccinimidyl oleate
CAS:<p>Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells.</p>Fórmula:C22H37NO7SPureza:98%Cor e Forma:SolidPeso molecular:459.6SRT3190
CAS:<p>SRT3190 is an antagonist of CXCR2.</p>Fórmula:C18H23F2N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:475.53Ipsalazide
CAS:<p>Ipsalazide is a novel salicylazosulfapyridine analog for the treatment of inflammatory bowel disease.</p>Fórmula:C16H11N3Na2O6Pureza:99.43%Cor e Forma:SolidPeso molecular:387.25SCH 546738
CAS:<p>SCH 546738 is an orally available, selective and potent CXCR3 antagonist that attenuates the development of autoimmune diseases and delays graft rejection.</p>Fórmula:C23H31Cl2N7OPureza:98.67%Cor e Forma:SolidPeso molecular:492.45AL 8697
CAS:<p>AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases.</p>Fórmula:C21H21F3N4OPureza:99.55% - 99.89%Cor e Forma:SolidPeso molecular:402.41(-)-Talarozole
CAS:<p>(-)-Talarozole is a potent retinoic acid metabolism inhibitor.</p>Fórmula:C21H23N5SCor e Forma:SolidPeso molecular:377.51AGN 205728
CAS:<p>AGN 205728 is a potent and selective RARγ antagonist (Ki: 3 nM; IC95: 0.6 nM) and has no inhibition on RARα and RARβ.</p>Fórmula:C29H27NO3Pureza:98%Cor e Forma:SolidPeso molecular:437.53GSK3-IN-3
CAS:<p>GSK3-IN-3 is a mitochondrial autophagy (mitophagy) inducer and GSK-3 inhibitor (IC50: 3.01 μM) that induces parkin-dependent mitochondrial autophagy.</p>Fórmula:C24H35N3O4Pureza:99.37%Cor e Forma:SolidPeso molecular:429.55Dinoprost
CAS:<p>Dinoprost (Prostaglandin F2a) is a naturally occurring prostaglandin. It is used in medicine to induce labor and as an abortifacient.</p>Fórmula:C20H34O5Pureza:97.94% - 98.04%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:354.48ABTL-0812
CAS:<p>ABTL-0812 induces endoplasmic reticulum (ER) stress-mediated autophagy, and with anti-cancer activity.</p>Fórmula:C18H32O3Cor e Forma:SolidPeso molecular:296.44K67
CAS:<p>K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.</p>Fórmula:C29H30N2O7S2Pureza:98.43%Cor e Forma:SolidPeso molecular:582.69(Rac)-AZD 6482
CAS:<p>(Rac)-AZD 6482 is the racemate of AZD 6482. AZD 6482 is a potent and selective inhibitor of p110β (IC50 of 0.69 nM).</p>Fórmula:C22H24N4O4Cor e Forma:SolidPeso molecular:408.45SR-17398
CAS:<p>SR-17398 is an inhibitor of Unc-51-Like Kinase 1 (ULK1) (IC50 = 22.4 uM).</p>Fórmula:C14H18N4OPureza:98%Cor e Forma:SolidPeso molecular:258.32Autophagy inducer 3
CAS:<p>Autophagy Inducer 3 triggers selective cancer cell death via autophagy, sparing healthy cells.</p>Fórmula:C24H43NO2Cor e Forma:SolidPeso molecular:377.6Evogliptin tartrate
CAS:<p>Evogliptin tartrate: Oral DPP-4 inhibitor, may treat atherosclerosis and diabetes.</p>Fórmula:C23H32F3N3O9Cor e Forma:SolidPeso molecular:551.51AC-55649
CAS:<p>AC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9.</p>Fórmula:C21H26O2Pureza:99.98%Cor e Forma:SolidPeso molecular:310.43MDK-6983
CAS:<p>MDK-6983 (MDK-6983) is an inhibitor of autophagy and disrupts the dynamics of actin cytoskeleton in human melanoma cells.</p>Fórmula:C22H18Cl2N2O3Pureza:99.68%Cor e Forma:SolidPeso molecular:429.3AMDE-1
CAS:<p>AMDE-1, an autophagy modulator, triggers Atg5-dependent autophagy, recruits Atg16, and induces LC3 lipidation.</p>Fórmula:C18H8ClF6N3Pureza:90%Cor e Forma:SolidPeso molecular:415.72SB02024
CAS:<p>SB02024 inhibits VPS34, boosts cGAS-STING, hinders autophagy, and shrinks breast cancer xenografts; enhances Sunitinib/Erlotinib efficacy.</p>Fórmula:C16H22F3N3O2Cor e Forma:SolidPeso molecular:345.36FAAH-IN-1
CAS:<p>FAAH-IN-1 is a fatty acid amide hydrolase (FAAH) inhibitor, with IC50s of 145 nM and 650 nM for rat and human FAAH, respectively.</p>Fórmula:C20H19ClN4OSPureza:98%Cor e Forma:SolidPeso molecular:398.91GPP78
CAS:<p>GPP78: Strong Nampt inhibitor, IC50 3.0 nM, depletes NAD. Kills SH-SY5Y cells, IC50 3.8 nM via autophagy. Anti-cancer and anti-inflammatory.</p>Fórmula:C27H29N5OPureza:98%Cor e Forma:SolidPeso molecular:439.553HOI-BA-01
CAS:<p>3HOI-BA-01 is a mammalian targeting effective rapamycin activation inhibitor.</p>Fórmula:C19H15NO5Pureza:98%Cor e Forma:SolidPeso molecular:337.33rac-NBI-74330
CAS:<p>rac-NBI-74330 is an effective and selective CXCR3 antagonist.</p>Fórmula:C32H27F4N5O3Pureza:99.6%Cor e Forma:SolidPeso molecular:605.58ACT-660602
CAS:<p>ACT-660602: Oral CXCR3 blocker, T-cell migration inhibitor, effective in acute lung injury models, potential for autoimmune research. IC50: 204 nM.</p>Fórmula:C20H20F6N8OSCor e Forma:SolidPeso molecular:534.48DK-1-49
CAS:<p>DK-1-49 is an autophagonizer. It causes accumulation of autophagy-associated LC3-II and enhanced levels of autophagosomes and acidic vacuoles.</p>Fórmula:C28H31N5O3S2Pureza:98%Cor e Forma:SolidPeso molecular:549.71AMG 487 (S-enantiomer)
CAS:<p>AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist.</p>Fórmula:C32H28F3N5O4Pureza:98%Cor e Forma:SolidPeso molecular:603.59SR12418
CAS:<p>SR12418 is a specific synthetic ligand for REV-ERBα (IC50 = 68 nM) and REV-ERBβ (IC50 = 119 nM) in TR-FRET assays. inhibits IL-17A expression in EL4 cells.</p>Fórmula:C31H30FNO3Pureza:99.96%Cor e Forma:SolidPeso molecular:483.57VUF10132
CAS:<p>VUF10132 is a full inverse CXCR3 N3.35A agonist.</p>Fórmula:C19H13BrCl4N2O2Pureza:98%Cor e Forma:SolidPeso molecular:523.03(R)-Hydroxychloroquine
CAS:<p>(R)-Hydroxychloroquine is the enantiomer of Hydroxychloroquine. Hydroxychloroquine is an agent of synthetic antimalarial.</p>Fórmula:C18H26ClN3OPureza:98%Cor e Forma:SolidPeso molecular:335.87AC-73
CAS:<p>AC-73, an oral CD147 inhibitor, blocks ERK1/2/STAT3/MMP-2 pathway, reducing liver cancer progression and leukemia cell growth.</p>Fórmula:C21H21NO2Pureza:98.95%Cor e Forma:SolidPeso molecular:319.4Atg4B-IN-2
CAS:<p>Atg4B-IN-2 is an Atg4B inhibitor with anticancer activity that inhibits Atg4B and PLA2 and resists the anticancer activity of resistant prostate cancer drugs.</p>Fórmula:C21H30O3Pureza:98.86%Cor e Forma:SolidPeso molecular:330.46GC7 Sulfate
CAS:<p>GC7 Sulfate blocks DHS, the sole enzyme activating eIF5A2, thus preventing eIF5A2 activation.</p>Fórmula:C8H22N4O4SPureza:99.85% - >99.99%Cor e Forma:SolidPeso molecular:270.35NUCC-390
CAS:<p>NUCC-390, a novel small-molecule CXCR4 receptor agonist, selectively induces CXCR4 receptor internalization while acting antagonistically to AMD3100.</p>Fórmula:C23H33N5OPureza:97.08%Cor e Forma:SolidPeso molecular:395.54Rosolutamide
CAS:<p>Rosolutamide (ALZ-003) is a curcumin analog, an Nrf1 and Nrf2 activator.</p>Fórmula:C28H32O6Pureza:95.48% - 99.15%Cor e Forma:SolidPeso molecular:464.55Apostatin-1
CAS:<p>Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD.</p>Fórmula:C19H27N3OSPureza:99.31%Cor e Forma:SolidPeso molecular:345.5CCT020312
CAS:<p>CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB.Cost-effective and quality-assured.</p>Fórmula:C31H30Br2N4O2Pureza:98.63%Cor e Forma:SolidPeso molecular:650.4CP-312
CAS:<p>CP-312 activates antioxidant defense, induces HMOX1, and shields human iPSC-derived cardiomyocytes from oxidative stress.</p>Fórmula:C16H12ClN3OS2Pureza:99.61%Cor e Forma:SolidPeso molecular:361.87Acetazolamide sodium
CAS:<p>Acetazolamide sodium (OT-302 sodium) is a potent carbonic anhydrase (CA) IX inhibitor used for indications such as epilepsy and altitude sickness.</p>Fórmula:C4H5N4NaO3S2Pureza:99.71% - 99.87%Cor e Forma:SolidPeso molecular:244.23MAPK13-IN-1
CAS:<p>MAPK13-IN-1 is a potent MAPK13 (p38δ) inhibitor (IC50: 620 nM).</p>Fórmula:C20H23N5O2Pureza:99.62%Cor e Forma:SolidPeso molecular:365.43
