Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1428 produtos de "Autofagia"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Zebularine
CAS:<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Fórmula:C9H12N2O5Pureza:99.04% - >99.99%Cor e Forma:SolidPeso molecular:228.2Cryptotanshinone
CAS:<p>Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.</p>Fórmula:C19H20O3Pureza:97.94% - ≥95%Cor e Forma:Orange Needle CrystalPeso molecular:296.36Idarubicin hydrochloride
CAS:<p>Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).</p>Fórmula:C26H27NO9·HClPureza:98.91% - 99.96%Cor e Forma:SolidPeso molecular:533.95GSK2606414
CAS:<p>GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.</p>Fórmula:C24H20F3N5OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:451.44Salubrinal
CAS:<p>Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 μM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2α).</p>Fórmula:C21H17Cl3N4OSPureza:97.25% - >99.99%Cor e Forma:SolidPeso molecular:479.81PTC-209
CAS:<p>PTC-209 is a potent and selective BMI-1 inhibitor.</p>Fórmula:C17H13Br2N5OSPureza:99.43% - 99.887%Cor e Forma:SolidPeso molecular:495.19S29434
CAS:<p>S29434 (NMDPEF) is a potent, competitiveinhibitor of quinone reductase 2 (QR2;IC50:5-16nM).</p>Fórmula:C21H18N4O3Pureza:99.92%Cor e Forma:SolidPeso molecular:374.39(+)-JQ-1
CAS:<p>(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.</p>Fórmula:C23H25ClN4O2SPureza:97.57% - ≥95%Cor e Forma:SolidPeso molecular:456.99Juglanin
CAS:<p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>Fórmula:C20H18O10Pureza:98.8% - 99.33%Cor e Forma:SolidPeso molecular:418.35LYS01
CAS:<p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>Fórmula:C23H23Cl2N5Pureza:98.28%Cor e Forma:SolidPeso molecular:440.37Meglutol
CAS:<p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>Fórmula:C6H10O5Pureza:99.73% - 99.94%Cor e Forma:SolidPeso molecular:162.14MRT68921 dihydrochloride
CAS:<p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>Fórmula:C25H36Cl2N6OPureza:98.91% - 99.92%Cor e Forma:SolidPeso molecular:507.499PH-797804
CAS:<p>PH-797804 is a pyridinone inhibitor of p38α (IC50: 26 nM, in a cell-free assay); 4-fold more selective versus p38β and does not inhibit JNK2.</p>Fórmula:C22H19BrF2N2O3Pureza:97.90% - 98.27%Cor e Forma:SolidPeso molecular:477.34,4'-Dimethoxychalcone
CAS:<p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>Fórmula:C17H16O3Pureza:99.57%Cor e Forma:SolidPeso molecular:268.31Hoechst 33342 trihydrochloride
CAS:<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Fórmula:C27H31Cl3N6OPureza:98.73% - ≥98%Cor e Forma:SolidPeso molecular:561.93Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Fórmula:C20H23BCl2N2O9Pureza:98.37% - >99.99%Cor e Forma:SolidPeso molecular:517.12MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Fórmula:C26H41N3O5Pureza:95% - 99.99%Cor e Forma:White To Off-White PowderPeso molecular:475.62Vps34-IN-1
CAS:<p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>Fórmula:C21H24ClN7OPureza:97.04%Cor e Forma:SolidPeso molecular:425.91SAR405
CAS:<p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>Fórmula:C19H21ClF3N5O2Pureza:99.42% - 99.79%Cor e Forma:SolidPeso molecular:443.85Vacuolin-1
CAS:<p>Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane.</p>Fórmula:C26H24IN7OPureza:97.20% - 98.45%Cor e Forma:SolidPeso molecular:577.42
