Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1428 produtos de "Autofagia"
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LYN-1604
CAS:<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Fórmula:C33H43Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:584.62SR9009
CAS:<p>SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.</p>Fórmula:C20H24ClN3O4SPureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:437.94NL-1
CAS:<p>NL-1 is a mitoNEET inhibitor with antileukemic effect.</p>Fórmula:C18H25NO3SPureza:98.64%Cor e Forma:SolidPeso molecular:335.46JH-II-127
CAS:<p>JH-II-127 is an oral LRRK2 inhibitor with IC50s: 6.6 nM (WT), 2.2 nM (G2019S), 47.7 nM (A2016T).</p>Fórmula:C19H21ClN6O3Pureza:98.32%Cor e Forma:SolidPeso molecular:416.86Kaempferol
CAS:<p>Kaempferol (Robigenin) is a natural flavonoid and an inverse agonist of ERRα and ERRγ.</p>Fórmula:C15H10O6Pureza:98% - 99.41%Cor e Forma:Yellow Needles From Alcohol And Water SolidPeso molecular:286.24Ruxolitinib
CAS:<p>Ruxolitinib (INCB018424) is a JAK1/2 inhibitor (IC50=3.3/2.8 nM) that is potent and selective.</p>Fórmula:C17H18N6Pureza:99.4% - >99.99%Cor e Forma:SolidPeso molecular:306.36DPN
CAS:<p>DPN (Diarylpropionitrile) is an selective agonist of estrogen receptor β (ERβ) .</p>Fórmula:C15H13NO2Pureza:99.01%Cor e Forma:Off-White SolidPeso molecular:239.27Silibinin
CAS:<p>Silibinin, main component in milk thistle, offers liver protection and shows anti-cancer potential in various human cells.</p>Fórmula:C25H22O10Pureza:97.98% - 98.37%Cor e Forma:SolidPeso molecular:482.44Nutlin-3a
CAS:<p>Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C30H30Cl2N4O4Pureza:95.62% - 99.71%Cor e Forma:SolidPeso molecular:581.49FIPI
CAS:<p>FIPI, a halopemide derivative, strongly blocks PLD1 and PLD2 (IC50s: 25 nM, 20 nM) and hinders PLD-mediated cell activity.</p>Fórmula:C23H24FN5O2Pureza:97.21% - 98.68%Cor e Forma:SolidPeso molecular:421.47Quercitrin
CAS:<p>Quercitrin (3-rhamnosyl quercetin) is a plant-derived flavonoid compound, displays antioxidant and anti-inflammatory activities.</p>Fórmula:C21H20O11Pureza:98.89% - 99.66%Cor e Forma:Yellow Crystals From Dil Methanol Or Ethanol SolidPeso molecular:448.38Quisinostat dihydrochloride
CAS:<p>Quisinostat dihydrochloride (JNJ26854165(Quisinostat) 2HCl) 是一种有口服活性，高效的 pan-HDAC 抑制剂，具有广泛的抗肿瘤活性。它对 HDAC1、HDAC2、HDAC4、HDAC10和HDAC11 的IC50值分别为 0.11 nM、0.33 nM、0.64 nM、0.46 nM 和 0.37 nM。</p>Fórmula:C21H28Cl2N6O2Pureza:97.13%Cor e Forma:SolidPeso molecular:467.39Tozasertib
CAS:<p>Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C).</p>Fórmula:C23H28N8OSPureza:99.99%Cor e Forma:SolidPeso molecular:464.59Regorafenib Hydrochloride
CAS:<p>Regorafenib HCl (BAY73-4506) is an oral inhibitor targeting angiogenic, stromal, and cancer kinases with strong antitumor effects.</p>Fórmula:C21H16Cl2F4N4O3Pureza:99.56%Cor e Forma:SolidPeso molecular:519.283-Bromopyruvic acid
CAS:<p>3-Bromopyruvic acid (Hexokinase II Inhibitor II, 3-BP) is a hexokinase II inhibitor with Ki of 2.4 mM for glycolysis/hexokinase inhibition.</p>Fórmula:C3H3BrO3Pureza:95% - 99.644%Cor e Forma:White To Pale Yellow Crystalline PowderPeso molecular:166.96Aloe emodin
CAS:<p>Aloe emodin (Rhabarberone) is an interferon-inducing agent, for JEV （IC50=1 μg/mL） and EV71（IC50=0.33 μg/mL ）.</p>Fórmula:C15H10O5Pureza:97.00%Cor e Forma:Orange SolidPeso molecular:270.24Fangchinoline
CAS:<p>Fangchinoline (Tetrandrine B) is extracted from Stephania tetrandra S. Moore.</p>Fórmula:C37H40N2O6Pureza:99.86% - >99.99%Cor e Forma:SolidPeso molecular:608.72AZD 6482
CAS:<p>AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.</p>Fórmula:C22H24N4O4Pureza:99.79% - 99.95%Cor e Forma:SolidPeso molecular:408.45Dioscin
CAS:<p>Dioscin (Collettiside III) is a saponin with antitumor activities.</p>Fórmula:C45H72O16Pureza:99.85% - 99.87%Cor e Forma:SolidPeso molecular:869.04GLPG1837
CAS:<p>GLPG1837 (ABBV-974) is an effective CFTR potentiator, with EC50s of 3 nM and 339 nM for F508del and G551D CFTR, respectively.</p>Fórmula:C16H20N4O3SPureza:99.64% - 99.91%Cor e Forma:SolidPeso molecular:348.42
