Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1428 produtos de "Autofagia"
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TA-02
CAS:<p>TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.TA-02 especially inhibits TGFBR-2.</p>Fórmula:C20H13F2N3Pureza:99.35% - 99.79%Cor e Forma:SolidPeso molecular:333.33Sepantronium bromide
CAS:<p>Sepantronium bromide (YM155) is a small-molecule proapoptotic agent with potential antineoplastic activity.</p>Fórmula:C20H19BrN4O3Pureza:99.68% - 99.85%Cor e Forma:SolidPeso molecular:443.26LY294002
CAS:<p>LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM).</p>Fórmula:C19H17NO3Pureza:98% - 99.96%Cor e Forma:Pale Yellow SolidPeso molecular:307.34Bafilomycin A1
CAS:<p>Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.</p>Fórmula:C35H58O9Pureza:95.87% - 99.36%Cor e Forma:SolidPeso molecular:622.83PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Fórmula:C16H17N3O4SPureza:98.74% - 99.19%Cor e Forma:SolidPeso molecular:347.39Belinostat
CAS:<p>Belinostat (PXD101) is an inhibitor of hydroxamic acid-type histone deacetylase (HDAC, IC50 of 27 nM in HeLa cell extracts),and with antineoplastic activity.</p>Fórmula:C15H14N2O4SPureza:99.75% - >99.99%Cor e Forma:SolidPeso molecular:318.353'-Hydroxypterostilbene
CAS:<p>3'-Hydroxypterostilbene suppresses colon cancer cell growth (COLO 205, HCT-116, HT-29) by triggering apoptosis and autophagy, affecting key pathways.</p>Fórmula:C16H16O4Pureza:98.25% - 99.19%Cor e Forma:SolidPeso molecular:272.3BIIB021
CAS:<p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>Fórmula:C14H15ClN6OPureza:98% - 99.82%Cor e Forma:SolidPeso molecular:318.76Quisinostat
CAS:<p>Quisinostat (JNJ-26481585), a second-gen HDAC inhibitor, is most potent for HDAC1 (IC50 0.11 nM) and selectively affects HDACs 2, 4, 10, and 11.</p>Fórmula:C21H26N6O2Pureza:96.01% - ≥98%Cor e Forma:SolidPeso molecular:394.47Sapanisertib
CAS:<p>Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.</p>Fórmula:C15H15N7OPureza:99.19% - >99.99%Cor e Forma:SolidPeso molecular:309.33Isodeoxyelephantopin
CAS:<p>Isodeoxyelephantopin can inhibit the growth of various tumor cells.</p>Fórmula:C19H20O6Pureza:99.88%Cor e Forma:SolidPeso molecular:344.36Veliparib
CAS:<p>Veliparib (ABT-888) (ABT-888) is an orally bioavailable inhibitor of PARP (Kis: 5.2/2.9 nM for PARP1/2). It enhances apoptosis and autophagy.</p>Fórmula:C13H16N4OPureza:98.66% - 99%Cor e Forma:SolidPeso molecular:244.29Pyriproxyfen
CAS:<p>Pyriproxyfen (S-31183) is an insecticide that acts as a biomimetic of juvenile hormone.</p>Fórmula:C20H19NO3Pureza:99.83%Cor e Forma:Solid CompactPeso molecular:321.37Flavopiridol hydrochloride
CAS:<p>Flavopiridol hydrochloride (MDL 107826A), an inhibitor of cyclin-dependent kinase, is a synthetic N-methylpiperidinyl chlorophenyl flavone compound.</p>Fórmula:C21H21Cl2NO5Pureza:98.87% - 99.88%Cor e Forma:SolidPeso molecular:438.3Orthanilamide
CAS:<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Fórmula:C6H8N2O2SPureza:99.72% - 99.96%Cor e Forma:White To Pale Cream Crystalline Powder Or CrystalsPeso molecular:172.2AGN 193109
CAS:<p>AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).</p>Fórmula:C28H24O2Pureza:99.87% - 99.89%Cor e Forma:SolidPeso molecular:392.49MPP+ iodide
CAS:<p>MPP+ iodide, a neurotoxin byproduct, mimics Parkinson's by killing substantia nigra neurons and affecting neuron transporters, inducing cell death.</p>Fórmula:C12H12INPureza:99.49% - 99.96%Cor e Forma:SolidPeso molecular:297.13Genistein
CAS:<p>Genistein (NPI 031L) is a natural soy isoflavone, a multi-targeted tyrosine kinase inhibitor. Genistein has antitumor effects. Cost effective and quality assured.</p>Fórmula:C15H10O5Pureza:98.22% - 99.64%Cor e Forma:Rectangular Or Six-Sided Rods From 60% Alcohol Dendritic Needles From Ether SolidPeso molecular:270.24(1E,6E)-Bis(demethoxy)curcumin
CAS:<p>(1E,6E)-Bis(demethoxy)curcumin (Curcumin III) is a natural demethoxy derivative of curcumin,with anti-inflammatory and anti-cancer activities.</p>Fórmula:C19H16O4Pureza:97.45%Cor e Forma:SolidPeso molecular:308.33GSK2578215A
CAS:<p>GSK2578215A is a potent and selective LRRK2 kinase inhibitor.</p>Fórmula:C24H18FN3O2Pureza:99.57% - 99.94%Cor e Forma:SolidPeso molecular:399.42
