Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1428 produtos de "Autofagia"
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BMS-582949 hydrochloride
CAS:<p>The BMS-582949 hydrochloride (BMS-582949 HCl) is a highly specific p38α MAPK inhibitor (IC50: 13 nM).</p>Fórmula:C22H27ClN6O2Pureza:97.57% - 98.75%Cor e Forma:SolidPeso molecular:442.95Tazarotene
CAS:<p>Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.</p>Fórmula:C21H21NO2SPureza:97.01% - 99.14%Cor e Forma:White SolidPeso molecular:351.46Deguelin
CAS:<p>Deguelin ((-)-Deguelin) is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.</p>Fórmula:C23H22O6Pureza:96.39% - 99.29%Cor e Forma:SolidPeso molecular:394.42BIA 10-2474
CAS:<p>BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.</p>Fórmula:C16H20N4O2Pureza:99.27%Cor e Forma:SolidPeso molecular:300.36Pirarubicin
CAS:<p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>Fórmula:C32H37NO12Pureza:97.80% - 99.15%Cor e Forma:Red Crystalline PowderPeso molecular:627.64kaempferide
CAS:<p>kaempferide (4'-Methylkaempferol) is an O-methylated flavonol present in Kaempferia kaempferi with antiviral activity.</p>Fórmula:C16H12O6Pureza:98.31% - 99.66%Cor e Forma:SolidPeso molecular:300.26SR12813
CAS:<p>SR12813 (GW 485801) is a pregnane X receptor (PXR) agonist.</p>Fórmula:C24H42O7P2Pureza:99.43%Cor e Forma:SolidPeso molecular:504.53GSK-690693
CAS:<p>GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.</p>Fórmula:C21H27N7O3Pureza:98.07% - 99.77%Cor e Forma:SolidPeso molecular:425.48Pantoprazole sodium
CAS:<p>Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.</p>Fórmula:C16H14F2N3NaO4SPureza:96.92% - 99.81%Cor e Forma:White To Off-White SolidPeso molecular:405.35LX2343
CAS:<p>LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.</p>Fórmula:C22H19ClN2O6SPureza:99.45%Cor e Forma:SolidPeso molecular:474.91PF-4708671
CAS:<p>PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).</p>Fórmula:C19H21F3N6Pureza:99.48% - 99.67%Cor e Forma:SolidPeso molecular:390.41Chelerythrine chloride
CAS:<p>Chelerythrine Chloride is a cell-permeable inhibitor of protein kinase C, competitive with respect to the phosphate acceptor and non-competitive with respect to</p>Fórmula:C21H18ClNO4Pureza:95% - 99.19%Cor e Forma:Yellow To Orange SolidPeso molecular:383.83Dehydropachymic acid
CAS:<p>Dehydropachymic acid shows antiinflammatory activity.</p>Fórmula:C33H50O5Pureza:99.61% - 99.78%Cor e Forma:SolidPeso molecular:526.75BI-D1870
CAS:<p>BI-D1870 is a highly specific, blood-brain-permeable, and ATP-competitive inhibitor of the N-terminal AGC kinase domain of RSK.Cost-effective and quality-assured.</p>Fórmula:C19H23F2N5O2Pureza:98.51% - 99.43%Cor e Forma:SolidPeso molecular:391.42VLX600
CAS:<p>VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent.</p>Fórmula:C17H15N7Pureza:98.62%Cor e Forma:SolidPeso molecular:317.35Ganoderic acid A
CAS:<p>Ganoderic acid A fights tumors, suppresses gene regulators, induces cancer cell death, and enhances cisplatin efficacy.</p>Fórmula:C30H44O7Pureza:99.31% - ≥95%Cor e Forma:SolidPeso molecular:516.67Notoginsenoside Fc
CAS:<p>1. Notoginsenoside Fc has perfect anti-platelet aggregatory effect.</p>Fórmula:C58H98O26Pureza:99.22% - 99.94%Cor e Forma:SolidPeso molecular:1211.38Cilofexor
CAS:<p>Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.</p>Fórmula:C28H22Cl3N3O5Pureza:99.86% - ≥95%Cor e Forma:SolidPeso molecular:586.85PAC-1
CAS:<p>PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer and Thoracic Cancers.</p>Fórmula:C23H28N4O2Pureza:96.78% - 99.77%Cor e Forma:SolidPeso molecular:392.49Bromocriptine mesylate
CAS:<p>Bromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)</p>Fórmula:C33H44BrN5O8SPureza:99.85% - 99.96%Cor e Forma:White SolidPeso molecular:750.7
