Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1431 produtos de "Autofagia"
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20-DEOXYINGENOL
CAS:<p>20-DEOXYINGENOL is a natual product.</p>Fórmula:C20H28O4Pureza:99.98% - ≥95%Cor e Forma:SolidPeso molecular:332.43Pseudolaric Acid B
CAS:<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Fórmula:C23H28O8Pureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:432.46U0126
CAS:<p>U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.</p>Fórmula:C18H16N6S2Pureza:99.61%Cor e Forma:White SolidPeso molecular:380.49Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Cor e Forma:SolidPeso molecular:607.62Clinofibrate
CAS:<p>Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.</p>Fórmula:C28H36O6Pureza:>99.99%Cor e Forma:White Crystalline PowderPeso molecular:468.58Alginic acid
CAS:<p>Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.</p>Fórmula:C14H22O13Pureza:≥98%Cor e Forma:SolidPeso molecular:398.317Oleanolic Acid
CAS:Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.Fórmula:C30H48O3Pureza:97.04% - 98.51%Cor e Forma:SolidPeso molecular:456.7Tetrahydrocurcumin
CAS:<p>Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.</p>Fórmula:C21H24O6Pureza:97.81% - 98.82%Cor e Forma:Solid PowderPeso molecular:372.41Salbutamol hemisulfate
CAS:<p>Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.</p>Fórmula:C13H21NO3H2O4SPureza:99.35%Cor e Forma:White Or Almost White Odourless PowderPeso molecular:576.70JZL195
CAS:<p>JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.</p>Fórmula:C24H23N3O5Pureza:99.81%Cor e Forma:SolidPeso molecular:433.46Acumapimod
CAS:<p>Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).</p>Fórmula:C22H19N5O2Pureza:≥95%Cor e Forma:SolidPeso molecular:385.42Lithocholic acid
CAS:Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!Fórmula:C24H40O3Pureza:98% - 99.93%Cor e Forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecular:376.57Scutellarein
CAS:<p>Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.</p>Fórmula:C15H10O6Pureza:98.02% - 99.63%Cor e Forma:SolidPeso molecular:286.24Vancomycin
CAS:<p>Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibiting</p>Fórmula:C66H75Cl2N9O24Pureza:98.76% - 99.35%Cor e Forma:Almost White PowderPeso molecular:1449.25URB-597
CAS:<p>URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.</p>Fórmula:C20H22N2O3Pureza:97.20% - 98.24%Cor e Forma:SolidPeso molecular:338.4Tropifexor
CAS:<p>Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.</p>Fórmula:C29H25F4N3O5SPureza:99.3% - 99.85%Cor e Forma:SolidPeso molecular:603.58Obeticholic Acid
CAS:Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.Fórmula:C26H44O4Pureza:99.88% - 99.97%Cor e Forma:SolidPeso molecular:420.63TG101209
CAS:<p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>Fórmula:C26H35N7O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:509.67Pifithrin-μ
CAS:Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.Fórmula:C8H7NO2SPureza:99.33% - 99.79%Cor e Forma:SolidPeso molecular:181.21Valinomycin
CAS:<p>Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin</p>Fórmula:C54H90N6O18Pureza:95.37% - 97.16%Cor e Forma:White SolidPeso molecular:1111.32
