Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1492 produtos de "Autofagia"
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ZX-29
CAS:ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.Fórmula:C23H28ClN7O3SPureza:98.32%Cor e Forma:SolidPeso molecular:518.03Ref: TM-T13416
1mg92,00€5mg230,00€10mg364,00€25mg620,00€50mg848,00€100mg1.121,00€200mg1.510,00€1mL*10mM (DMSO)264,00€Trimetazidine dihydrochloride
CAS:Trimetazidine, an anti-ischemic agent, enhances myocardial glucose use, inhibits fat metabolism, and helps with angina.Fórmula:C14H24Cl2N2O3Pureza:99.58%Cor e Forma:Crystalline SolidPeso molecular:339.258LG-100064
CAS:LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)Fórmula:C23H26O3Pureza:98.65%Cor e Forma:SolidPeso molecular:350.45Ref: TM-T11844
2mg44,00€5mg66,00€10mg92,00€25mg164,00€50mg235,00€100mg350,00€200mg515,00€1mL*10mM (DMSO)73,00€Felodipine
CAS:Felodipine (CGH-869) is a longlasting 1, 4-dihydropyridine calcium channel repressor.Fórmula:C18H19Cl2NO4Pureza:99.91%Cor e Forma:SolidPeso molecular:384.25Ref: TM-T0145
2mg34,00€5mg50,00€10mg67,00€25mg96,00€50mg123,00€100mg168,00€500mg409,00€1mL*10mM (DMSO)54,00€Sulfadoxine
CAS:Sulfadoxine (Sulphadoxine) is a broad-spectrum sulfanilamide and a synthetic analog of para-aminobenzoic acid (PABA) with bacteriostatic and antimalarialFórmula:C12H14N4O4SPureza:99.67%Cor e Forma:White Or White Crystalline PowderPeso molecular:310.33Sulindac
CAS:Sulindac (Sulindac sulfoxide) is a sulfinylindene derivative prodrug with potential antineoplastic activity.Fórmula:C20H17FO3SPureza:99.09% - 99.15%Cor e Forma:Yellow SolidPeso molecular:356.41Doxorubicin hydrochloride
CAS:Doxorubicin hydrochloride (Adriamycin) belongs to the anthracycline class of antibiotics and is an inhibitor of human DNA topoisomerase I/II (IC50=0.8/2.67 μM).Fórmula:C27H29NO11·HClPureza:98% - 99.52%Cor e Forma:Orange-Red At Neutral Phs And Violet Blue Over Ph 9 (Ntp 1992)Peso molecular:579.99Luteolin
CAS:Luteolin (Luteolol) belongs to the flavonoid group of natural products and is a Nrf2 inhibitor, PDE inhibitor.Fórmula:C15H10O6Pureza:96.61% - 99.71%Cor e Forma:SolidPeso molecular:286.24Oxidopamine hydrobromide
CAS:Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.Fórmula:C8H12BrNO3Pureza:98.22% - 99.88%Cor e Forma:Beige To Brown Fine Crystalline PowderPeso molecular:250.09Isoliquiritigenin
CAS:Isoliquiritigenin (ISL) is a natural flavonoid that inhibits influenza virus and aldose reductase. Isoliquiritigenin has antitumor effect. Cost-effective and quality-assured.Fórmula:C15H12O4Pureza:97.61% - 99.44%Cor e Forma:PowderPeso molecular:256.25Erlotinib hydrochloride
CAS:Erlotinib hydrochloride (NSC 718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.Fórmula:C22H23N3O4·HClPureza:99.78% - 99.85%Cor e Forma:White Or Off-White PowderPeso molecular:429.9Honokiol
CAS:Honokiol (NSC-293100) is the active principle of magnolia extract. It inhibits the activation of Akt and enhances the phosphorylation of ERK1/ERK2.Fórmula:C18H18O2Pureza:99.65% - 99.94%Cor e Forma:Dark Brown To White Fine Powder With Pleasant Odor Spicy And Slightly Bitter TastePeso molecular:266.33Pyrazinamide
CAS:Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amideFórmula:C5H5N3OPureza:99.71% - 99.9%Cor e Forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Peso molecular:123.11Dilmapimod
CAS:Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic obstructive pulmonary disease.Fórmula:C23H19F3N4O3Pureza:97.53%Cor e Forma:SolidPeso molecular:456.42Daunorubicin hydrochloride
CAS:Daunorubicin hydrochloride (Rubidomycin hydrochloride), an anthracycline aminoglycoside antineoplastic, inhibits DNA replication and repair and RNA and proteinFórmula:C27H29NO10·HClPureza:96.21% - 99.53%Cor e Forma:Cancer DrugPeso molecular:563.99Ref: TM-T1511
5mg34,00€10mg52,00€25mg87,00€50mg113,00€100mg177,00€200mg281,00€500mg442,00€1mL*10mM (DMSO)59,00€Amiodarone hydrochloride
CAS:Amiodarone HCl: Antianginal, class III antiarrhythmic. Lengthens heart muscle action, slows heart rate, reduces vascular resistance.Fórmula:C25H29I2NO3·HClPureza:99.82% - ≥95%Cor e Forma:White To Cream Crystalline PowderPeso molecular:681.78Itraconazole
CAS:Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.Fórmula:C35H38Cl2N8O4Pureza:98% - 99.90%Cor e Forma:Off-White Crystalline SolidPeso molecular:705.63Lomustine
CAS:Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.Fórmula:C9H16ClN3O2Pureza:98.36% - 99.44%Cor e Forma:Solid SolidPeso molecular:233.7Baicalin
CAS:Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from scutellaria baicalensis, with antioxidant, anti-tumor, anti-HIVFórmula:C21H18O11Pureza:90.08% - 99.32%Cor e Forma:Yellow PowderPeso molecular:446.36Ref: TM-T2775
1g80,00€2g102,00€5g152,00€50mg34,00€100mg49,00€200mg49,00€500mg55,00€1mL*10mM (DMSO)50,00€Clofarabine
CAS:Clofarabine (Clofarex)m, a second generation purine nucleoside analog with antineoplastic activity, inhibits the enzymatic activities of ribonucleotideFórmula:C10H11ClFN5O3Pureza:99.94% - >99.99%Cor e Forma:White SolidPeso molecular:303.68Ref: TM-T0297
5mg40,00€10mg56,00€25mg90,00€50mg126,00€100mg163,00€200mg205,00€500mg341,00€1mL*10mM (DMSO)52,00€
