Receptor de Bombesina
Os receptores de bombesina são um grupo de GPCRs ativados por peptídeos semelhantes à bombesina, que estão envolvidos na regulação da função gastrointestinal, do equilíbrio energético e da proliferação celular. Esses receptores são de particular interesse na pesquisa do câncer, pois são frequentemente superexpressos em certos tipos de tumores. Antagonistas de receptores de bombesina são estudados por seu potencial como terapêuticos contra o câncer. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de bombesina de alta qualidade para apoiar sua pesquisa em oncologia, fisiologia gastrointestinal e sinalização de receptores.
Foram encontrados 35 produtos de "Receptor de Bombesina"
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Litorin acetate(55749-97-8 Free base)
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.Fórmula:C53H72N14O13SPureza:98.61%Cor e Forma:SolidPeso molecular:1145.29Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Fórmula:C45H44O11Pureza:97.09% - 97.99%Cor e Forma:SolidPeso molecular:760.82Bombesin acetate(31362-50-2 free base)
CAS:Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina).Fórmula:C73H114N24O20SPureza:98.44%Cor e Forma:SolidPeso molecular:1679.92BA 1 acetate(183241-31-8 free base)
BA 1 acetate: bombesin agonist, IC50s: 0.26/1.55/2.52 nM (BB1/BB2/BB3), boosts glucose transport, promotes lung cancer cell growth in vitro.Fórmula:C59H80N14O13Pureza:95.3%Cor e Forma:SolidPeso molecular:1193.35[D-Phe12,Leu14]-Bombesin acetate
[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.Fórmula:C77H118N22O20Pureza:98.41% - 99.14%Cor e Forma:SolidPeso molecular:1671.9[D-Phe12]-Bombesin acetate
[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.Fórmula:C76H116N22O20SPureza:99.81%Cor e Forma:SolidPeso molecular:1689.94kuwanon G
CAS:Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.Fórmula:C40H36O11Pureza:98% - 99.57%Cor e Forma:SolidPeso molecular:692.71Ref: TM-T3S1612
1mg63,00€5mg138,00€1mL*10mM (DMSO)178,00€10mg198,00€25mg321,00€50mg465,00€100mg627,00€200mg845,00€Litorin
CAS:Litorin suppresses appetite and stimulates smooth muscle, gastrin, gastric acid, and pancreatic secretion.Fórmula:C51H68N14O11SCor e Forma:White PowderPeso molecular:1085.24MK-5046
CAS:MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).Fórmula:C20H18F6N4OPureza:98.56%Cor e Forma:SolidPeso molecular:444.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Fórmula:C23H24N2O7Pureza:98%Cor e Forma:SolidPeso molecular:440.45Bag-1
CAS:Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist.Fórmula:C22H27N3Cor e Forma:SolidPeso molecular:333.47PD 168368
CAS:PD 168368 is a mixed neuromodulin B receptor (NMB-R) antagonist and potent FPR1/FPR2/FPR3 agonist that inhibits the gastrin-releasing peptide receptor.Fórmula:C31H34N6O4Pureza:98.11% - 99.87%Cor e Forma:SolidPeso molecular:554.64Ref: TM-T8691
1mg84,00€5mg167,00€1mL*10mM (DMSO)197,00€10mg245,00€25mg492,00€50mg737,00€100mg1.054,00€PD 165929
CAS:PD 165929 is a selective antagonist of Bombesin BB1.Fórmula:C37H47N5O2Pureza:98%Cor e Forma:SolidPeso molecular:593.8GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Fórmula:C29H33F3N4O4Cor e Forma:SolidPeso molecular:558.59GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Fórmula:C28H32F3N5O4Cor e Forma:SolidPeso molecular:559.58
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