Receptor de Histamina
Os receptores de histamina são GPCRs que mediam os efeitos da histamina, uma amina biogênica envolvida em respostas imunológicas, secreção de ácido gástrico e neurotransmissão. Existem quatro subtipos de receptores de histamina (H1, H2, H3 e H4), cada um desempenhando papéis distintos em reações alérgicas, função gástrica e atividade do sistema nervoso central. Antagonistas dos receptores de histamina são amplamente utilizados no tratamento de alergias, úlceras pépticas e enjoo de movimento. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores de histamina de alta qualidade para apoiar sua pesquisa em imunologia, gastroenterologia e neurofarmacologia.
Foram encontrados 390 produtos para "Receptor de Histamina".
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BL 6341A
CAS:BL 6341A is related to Tumor data and H2-antagonists or anti-histaminsFórmula:C9H14N8OS3Cor e Forma:SolidPeso molecular:346.46(R)-Azelastine
CAS:(R)-Azelastine, an antihistamine, reduces H1R, M1R, M3R levels and inhibits HNEpC growth.Fórmula:C22H24ClN3OCor e Forma:SolidPeso molecular:381.9Noberastine maleate
CAS:Noberastine maleate, a fast-acting furan-derived H1 antagonist, peaks at 4 hours with minimal CNS effects and maximal efficacy at 30 mg/day.Fórmula:C25H29N5O9Cor e Forma:SolidPeso molecular:543.53ROS 234 dioxalate
CAS:ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor)Fórmula:C17H19N5O8Pureza:98%Cor e Forma:SolidPeso molecular:421.37Fenspiride-D5
CAS:Fenspiride-d5: internal standard for GC/LC-MS quantification, H1 antagonist, NSAID, anti-inflammatory, selective PDE4,5,3 inhibitor.Fórmula:C15H15D5N2O2Cor e Forma:SolidPeso molecular:265.36Dacemazine
CAS:Dacemazine is used to treat depression.Fórmula:C16H16N2OSCor e Forma:SolidPeso molecular:284.38VUF14738
CAS:VUF14738 is a robust and fatigue-resistant photoswitchable GPCR antagonist.Fórmula:C25H32N4O2Cor e Forma:SolidPeso molecular:420.55Dothiepin HCl
CAS:Dothiepin HCl: TCA, SNRI, with antihistamine, antiadrenergic, anticholinergic, and sodium block properties.Fórmula:C19H22ClNSCor e Forma:SolidPeso molecular:331.9KY 234
CAS:KY 234 is a thromboxane synthetase antagonist.Fórmula:C33H35N5O2Cor e Forma:SolidPeso molecular:533.676(S)-Azelastine
CAS:(S)-Azelastine is an antihistamine reducing receptors H1R, M1R, M3R, and inhibiting HNEpC cell growth.Fórmula:C22H24ClN3OCor e Forma:SolidPeso molecular:381.9FRG8701
CAS:FRG8701 is a new Histamine H2-receptor antagonist with an IC50 of ranging from 0.25 to 0.43 μM.Fórmula:C22H30N2O4SPureza:98%Cor e Forma:SolidPeso molecular:418.55ReN-1869 hydrochloride
CAS:ReN 1869 hydrochloride is a novel, selective antagonist of histamine H1 receptor.Fórmula:C24H28ClNO2Pureza:98%Cor e Forma:SolidPeso molecular:397.94Azelastine
CAS:Azelastine (Azelastinum) is a phthalazine derivative, and is an histamine antagonist and mast cell stabilizer.Fórmula:C22H24ClN3OPureza:99.35% - 99.99%Cor e Forma:White SolidPeso molecular:381.90BMY-25271
CAS:BMY-25271 is an antagonist of histamine H2 receptor.Fórmula:C12H19N5O2S2Pureza:98%Cor e Forma:SolidPeso molecular:329.44SDZ 205-557 hydrochloride
CAS:5-HT3/5-HT4 receptor antagonistFórmula:C14H22Cl2N2O3Pureza:99.34%Cor e Forma:Green SolidPeso molecular:337.24Mianserin
CAS:Mianserin, an H1 receptor reverse agonist, is a psychoactive compound in the tetracyclic antidepressant (TeCA) treatment family.Fórmula:C18H20N2Pureza:99.85%Cor e Forma:SolidPeso molecular:264.36Wy 49051
CAS:Wy 49051 is an orally active antagonist of H1 receptor(IC50 of 44 nM).Fórmula:C28H33N5O3Pureza:99.89%Cor e Forma:Yellow SolidPeso molecular:487.59Ref: TM-T13352
1mg99,00€5mg188,00€1mL*10mM (DMSO)207,00€10mg273,00€25mg427,00€50mg575,00€100mg743,00€200mg990,00€PF-03654746
CAS:PF-03654746: selective H3 antagonist, boosts cognition in Alzheimer's, may treat allergic rhinitis.Fórmula:C18H24F2N2OPureza:99.57% - 99.98%Cor e Forma:SolidPeso molecular:322.39PF 03654746 FA
PF 03654746 FA is a human histamine receptor H(3) antagonist that can be used to study cognitive impairment and Alzheimer's disease.Fórmula:C19H26F2N2O3Pureza:99.44%Cor e Forma:White OilPeso molecular:368.42Niperotidine
CAS:Niperotidine is an antagonist of histamine H2-receptor.Fórmula:C20H26N4O5SPureza:98%Cor e Forma:SolidPeso molecular:434.51ROS 234
CAS:ROS 234 is a potent H3 antagonist with pKB 9.46 for Guinea-pig ileum and pKi 8.90 for Rat cortex; ED50 of 19.12 mg/kg in rats, but with limited central access.Fórmula:C13H15N5Cor e Forma:SolidPeso molecular:241.29JNJ 10181457 dihydrochloride
CAS:JNJ 10181457 dihydrochloride is a Histamine H3 receptor antagonist.Fórmula:C20H28N2OPureza:98%Cor e Forma:SolidPeso molecular:312.45OUP-186
CAS:OUP-186 is a selective H3 receptor antagonist that suppresses breast cancer cell growth with an IC50 of ~50 μM and induces apoptosis.Fórmula:C19H30ClN3SCor e Forma:SolidPeso molecular:367.98Vapitadine dihydrochloride
CAS:Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.Fórmula:C17H22Cl2N4OPureza:98.28% - 99.85%Cor e Forma:SolidPeso molecular:369.29A-304121
CAS:A-304121 is a histamine H(3) receptor.Fórmula:C20H29N3O3Cor e Forma:SolidPeso molecular:359.46(R)-Mequitazine
CAS:(R)-Mequitazine, a muscarinic acetylcholine receptor (M-AChRs) antagonist, is used potentially for the treatment of asthma.Fórmula:C20H22N2SCor e Forma:SolidPeso molecular:322.47ABT-239
CAS:ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists.Fórmula:C22H22N2OPureza:99.94%Cor e Forma:SolidPeso molecular:330.42Ref: TM-T14087
1mg44,00€1mL*10mM (DMSO)90,00€5mg93,00€10mg133,00€25mg270,00€50mg409,00€100mg595,00€200mg833,00€Zolantidine dimaleate
CAS:Zolantidine dimaleate is a potent and selective histamine H2 receptor antagonist. Zolantidine dimaleate exhibits excellent blood-brain barrier permeability and effectively suppresses H2 receptor-mediated responses across various preclinical models to facilitate the study of histaminergic neurotransmission in the brain.Fórmula:C26H31N3O5SPureza:98%Cor e Forma:White SolidPeso molecular:497.61Alimemazine
CAS:Alimemazine, an antipruritic and HA-receptor antagonist, also partially activates H1R and other GPCRs.Fórmula:C18H22N2SPureza:98%Cor e Forma:SolidPeso molecular:298.45JNJ-10191584
CAS:JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammationFórmula:C13H15ClN4OCor e Forma:SolidPeso molecular:278.74Zaltidine
CAS:Zaltidine is an antagonist of H2-receptor, and has the antisecretory action.Fórmula:C8H10N6SPureza:98%Cor e Forma:SolidPeso molecular:222.27Adriforant
CAS:Adriforant (PF-3893787,ZPL-3893797) is a competitive histamine receptor 4 h4 antagonist that antagonizes histamine-induced phosphorylation of ERK, inflammation.Fórmula:C13H22N6Pureza:99.84%Cor e Forma:SolidPeso molecular:262.35VUF 8328
CAS:VUF 8328 is an agonist of histamine H(3) receptor.Fórmula:C7H12N4SPureza:98%Cor e Forma:SolidPeso molecular:184.26Proxyfan
CAS:Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.Fórmula:C13H16N2OPureza:99.68%Cor e Forma:SolidPeso molecular:216.28Abt-288
CAS:ABT-288 is a selective and potent H3 antagonist for the treatment of mild to moderate Alzheimer's dementia.Fórmula:C23H24N4OPureza:98.17% - 98.49%Cor e Forma:SolidPeso molecular:372.46Pitolisant
CAS:Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.Fórmula:C17H26ClNOPureza:99.95%Cor e Forma:SolidPeso molecular:295.85Ref: TM-T60636
5mg46,00€1mL*10mM (DMSO)49,00€10mg66,00€25mg114,00€50mg178,00€100mg295,00€500mg708,00€KSK68
CAS:KSK68 is a sigma-1 and histamine H3 receptor antagonist with analgesic activity, inhibits H3 receptors and can be used to study pain.Fórmula:C23H28N2O2Pureza:99.11%Cor e Forma:SolidPeso molecular:364.48Impromidine hydrochloride
CAS:Impromidine hydrochloride is a very potent and specific histamine H2 receptor agonist for conducting cardiovascular studies.Fórmula:C14H26Cl3N7SPureza:99.82%Cor e Forma:Yellow OilPeso molecular:430.83Bavisant
CAS:Bavisant (JNJ-31001074) is a selective and orally active Human H3 receptor antagonist.Fórmula:C19H27N3O2Pureza:99.21% - 99.65%Cor e Forma:SolidPeso molecular:329.44D18024
CAS:D18024 is a phthalazinonderivat with anti-allergic and anti-histamine effect.Fórmula:C29H31ClFN3OPureza:99.86%Cor e Forma:White SolidPeso molecular:492.03Ref: TM-T10945
1mg349,00€5mg697,00€1mL*10mM (DMSO)880,00€10mg888,00€25mg1.395,00€50mg1.783,00€100mg2.530,00€NP10679
CAS:NP10679 is a N-methyl-D-aspartate (NMDA) receptor inhibitor of the GluN2B subunit that inhibits histamine H1, hERG channels, and CYPase.Fórmula:C23H26F3N3O3Pureza:99.98%Cor e Forma:SolidPeso molecular:449.47Irdabisant
CAS:Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.Fórmula:C18H23N3O2Pureza:99.96%Cor e Forma:White SolidPeso molecular:313.39Antihistamine-1
CAS:Antihistamine-1 是能够渗透血脑屏障的 H1-抗组胺药 (Ki=6.9 nM), 它也是 CYP2D6 和 hERG 通道的抑制剂，其 IC50 值分别为 5.4 和 0.8 μM。Fórmula:C23H24FN5Pureza:99.69%Cor e Forma:SolidPeso molecular:389.47Noberastine
CAS:Noberastine (R 64947) is a novel histamine H1 antagonist with potent and specific peripheral antihistamine activity.Fórmula:C17H21N5OPureza:99.72% - >99.99%Cor e Forma:SolidPeso molecular:311.38Eclazolast
CAS:Eclazolast (RHC 2871), a lipophilic anti-allergic, inhibits mast cell mediator release by affecting Fc(epsilon)RI-related processes, dose-dependently.Fórmula:C12H12ClNO4Pureza:98.29% - 98.61%Cor e Forma:SolidPeso molecular:269.68Ref: TM-T25360
1mg112,00€1mL*10mM (DMSO)249,00€5mg261,00€10mg396,00€25mg655,00€50mg888,00€100mg1.251,00€500mg2.493,00€JZP-361
CAS:JZP-361: selective MAGL inhibitor (IC50 = 46 nM); weaker on FAAH, hABHD6; anti-histamine; for asthma research.Fórmula:C22H20ClN5OPureza:99.82%Cor e Forma:SolidPeso molecular:405.88KSK94
CAS:KSK94 is an H3 receptor antagonist that inhibits sigma-2 receptors , with a Ki value of 75.2 nM, and can be used to study injurious pain.Fórmula:C25H26N4OPureza:99.60%Cor e Forma:SolidPeso molecular:398.5Clemastine
CAS:Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects.Fórmula:C21H26ClNOPureza:99.21%Cor e Forma:Transparent OilPeso molecular:343.89ReN-1869
CAS:ReN-1869 is a novel selective histamine H(1) receptor antagonist with anti-neurogenic pain and anti-inflammatory activity for the study of neurological diseasesFórmula:C24H27NO2Pureza:99.83% - 99.98%Cor e Forma:SolidPeso molecular:361.48
