Receptor de Histamina
Os receptores de histamina são GPCRs que mediam os efeitos da histamina, uma amina biogênica envolvida em respostas imunológicas, secreção de ácido gástrico e neurotransmissão. Existem quatro subtipos de receptores de histamina (H1, H2, H3 e H4), cada um desempenhando papéis distintos em reações alérgicas, função gástrica e atividade do sistema nervoso central. Antagonistas dos receptores de histamina são amplamente utilizados no tratamento de alergias, úlceras pépticas e enjoo de movimento. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores de histamina de alta qualidade para apoiar sua pesquisa em imunologia, gastroenterologia e neurofarmacologia.
Foram encontrados 385 produtos de "Receptor de Histamina"
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GT-2331
CAS:GT-2331 is a histamine H3 receptor antagonist.Fórmula:C14H20N2Cor e Forma:SolidPeso molecular:216.32APD-916
CAS:APD-916, an H3 receptor antagonist, exhibits favorable pharmacokinetic properties. Oral administration of APD-916 has been demonstrated to enhance wakefulness in various animal models.Fórmula:C23H31NO3SCor e Forma:SolidPeso molecular:401.56Embramine hydrochloride
CAS:Embramine hydrochloride is a monoethanolamine derivative utilized for its antihistaminic and anticholinergic properties [1].Fórmula:C18H23BrClNOCor e Forma:SolidPeso molecular:384.74JNJ-28583867
CAS:JNJ-28583867 is an inhibitor of histamine H(3) receptor antagonist and serotonin reuptake.Fórmula:C24H32N2O2SCor e Forma:SolidPeso molecular:412.59GSK-1004723
CAS:GSK-1004723 is a novel antagonist of histamine H(1) and H(3) receptor. It represents a potential novel therapy for allergic rhinitis.Fórmula:C39H49ClN4O2Cor e Forma:SolidPeso molecular:641.28Cipralisant
CAS:Cipralisant: H3 receptor antagonist (in vivo), agonist (in vitro, pKi 9.9), Ki 0.47 nM in rats, may treat ADHD.Fórmula:C14H20N2Pureza:98%Cor e Forma:SolidPeso molecular:216.32Hydroxydione
CAS:Hydroxydione, a neuroactive steroid with general anesthetic properties, is utilized in anesthesia-related research [1] [2].Fórmula:C21H32O3Cor e Forma:SolidPeso molecular:332.48Cipralisant maleate
CAS:Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist.Fórmula:C18H24N2O4Cor e Forma:SolidPeso molecular:332.39H3 receptor antagonist 1
CAS:H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist.Fórmula:C20H28F2N2OPureza:98%Cor e Forma:SolidPeso molecular:350.45Levocabastine
CAS:Levocarbastine: 2nd-gen H1 antagonist, treats allergic conjunctivitis, selective NTS2 neurotensin inhibitor.Fórmula:C26H29FN2O2Cor e Forma:SolidPeso molecular:420.52H4R antagonist 2
CAS:H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoidFórmula:C13H17N5OPureza:98%Cor e Forma:SolidPeso molecular:259.31ST-1006
CAS:ST-1006: histamine H4 agonist, pKi 7.94, anti-inflammatory, anti-pruritic, promotes basophil migration.Fórmula:C16H20Cl2N6Pureza:99.96% - 99.98%Cor e Forma:SolidPeso molecular:367.28Enerisant
CAS:Enerisant (TS-091) is a histamine H3 receptor antagonist that promotes pro-cognitive effects and reverses scopolamine-induced cognitive deficits.Fórmula:C22H30N4O3Pureza:99.7%Cor e Forma:SoildPeso molecular:398.50H3R antagonist 1
CAS:H3R-IN-1 is an effective inverse agonist of the histamine receptor 3 (H3R).Fórmula:C19H23N3O3Cor e Forma:SolidPeso molecular:341.4Tixanox sodium
CAS:Tixanox sodium effectively blocks histamine release in the lungs triggered by anti-IgE. It has also been demonstrated that when administered orally, Tixanox sodium can successfully counteract exercise-induced asthma.Fórmula:C15H9NaO5SCor e Forma:SolidPeso molecular:324.28H3R antagonist 5
CAS:H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.Fórmula:C23H32N2O4Cor e Forma:SolidPeso molecular:400.511CI-624
CAS:CI-624 reduces the secretion and output of hydrogen ions, sodium ions, potassium ions, and pepsin. This compound may be utilized in research focusing on cancer and autoimmune diseases.Fórmula:C8H8N2SCor e Forma:SolidPeso molecular:164.228H1R ligand-1
CAS:<p>H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.</p>Fórmula:C19H23NOCor e Forma:SolidPeso molecular:281.392Sitamaquine hydrochloride
CAS:Sitamaquine hydrochloride (WR 6026) is an orally active 8-aminoquinoline analog with antileishmanial activity. This compound inhibits mitochondrial complex II (succinate dehydrogenase) and is characterized by its lipophilic weak base properties. It rapidly accumulates in the acidic compartments of Leishmania parasites, predominantly localizing within the acidocalcisomes.Fórmula:C21H35Cl2N3OCor e Forma:SolidPeso molecular:416.43Arpromidine
CAS:Arpromidine (BU-E-50) acts as an agonist for the histamine H2 receptor and an antagonist for the histamine H1 receptor. It demonstrates positive inotropic effects with a lower risk of inducing arrhythmias. Arpromidine can be utilized in studies related to congestive heart failure.Fórmula:C21H25FN6Cor e Forma:SolidPeso molecular:380.462
