Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 298 produtos de "Receptor opioide"
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BU72
CAS:<p>BU72 is a potent, long-lasting agonist for μ and κ opioid receptors, with partial agonistic activity at the δ opioid receptor (EC50 values of 0.054, 0.033, and 0.58 nM, respectively). It provides strong, enduring analgesic effects primarily mediated through μ opioid receptors. BU72 also exhibits a prolonged duration of activity and can partially reverse morphine-induced analgesia. It is applicable in studies of opioid dependence.</p>Fórmula:C28H32N2O2Cor e Forma:SolidPeso molecular:428.57SC13
CAS:<p>SC13, a novel mitragynine analog, exhibits low-efficacy agonism at Mu opioid receptors and provides antinociception while minimizing adverse effects.</p>Fórmula:C26H30N2O5Cor e Forma:SolidPeso molecular:450.53RX 809055AX
CAS:<p>RX 809055AX is a long lasting opioid antagonist at mu and delta receptors.</p>Fórmula:C29H29ClN2O4Cor e Forma:SolidPeso molecular:505Anilopam
CAS:<p>Anilopam is an opioid analgesic belonging to the benzazepine class and acts as an agonist at opioid receptors.</p>Fórmula:C20H26N2OCor e Forma:SolidPeso molecular:310.43GNTI dihydrochloride
CAS:<p>κ opioid receptor antagonist</p>Fórmula:C27H30ClN5O3Pureza:98%Cor e Forma:SolidPeso molecular:508.0122-Thiocyanatosalvinorin A
CAS:<p>22-Thiocyanatosalvinorin A (RB-64) is a potent selective agonist for the kappa-opioid receptor, exhibiting an EC50 value of 0.077 nM.</p>Fórmula:C24H27NO8SCor e Forma:SolidPeso molecular:489.54CCG258747
CAS:CCG258747 is a novel, selective inhibitor of the GRK2 subfamily.Fórmula:C28H27FN4O4Cor e Forma:SolidPeso molecular:502.54BNTX
CAS:<p>BNTX (7-Benzylidenenaltrexone) is a selective δ1-opioid receptor antagonist. It competitively counteracts the antisecretory effects of DPDPE, Deltorphin 2, and DAMGO. BNTX is applicable in research focused on antinociceptive effects.</p>Fórmula:C27H27NO4Cor e Forma:SolidPeso molecular:429.508rel-SB-612111 hydrochloride
CAS:<p>NOP receptor antagonist</p>Fórmula:C24H30Cl3NOPureza:98%Cor e Forma:SolidPeso molecular:454.86JDTic Dihydrochloride
CAS:JDTic Dihydrochloride is a high-affinity and selective κ-opioid receptor (KOR) antagonist that blocks dynorphin-KOR signalling,antidepressant.Fórmula:C28H41Cl2N3O3Pureza:98%Cor e Forma:SolidPeso molecular:538.55Naldemedine tosylate
CAS:<p>Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.</p>Fórmula:C39H42N4O9SCor e Forma:SolidPeso molecular:742.84J-113397
CAS:<p>J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).</p>Fórmula:C24H37N3O2Pureza:98%Cor e Forma:SolidPeso molecular:399.57Allyphenyline oxalate
CAS:<p>The pKi values of Allyphenyline oxalate (compound 9) for the α2-adrenergic receptor subtypes α2A, α2B, and α2C are 7.24, 6.47, and 7.07, respectively.</p>Fórmula:C16H20N2O5Cor e Forma:SolidPeso molecular:320.34σ1 Receptor/μ Opioid receptor modulator 2
CAS:<p>Compound 4x, also known as σ1 Receptor/μOpioid receptormodulator 2, acts as a μOR agonist and a σ1R antagonist, exhibiting a potent μOR EC50 of 0.6 nM and strong σ1R inhibitory activity (Ki: 363.7 nM). It demonstrates significant analgesic effects in various pain models.</p>Fórmula:C23H31N3OPeso molecular:365.51DS34942424
<p>DS34942424 is an orally potent analgesic which did not exhibit mu opioid receptor agonist activity.</p>Fórmula:C15H17FN2OCor e Forma:SolidPeso molecular:260.315′-Guanidinonaltrindole
CAS:<p>5′-Guanidinonaltrindole (GNTI) is a selective antagonist of the kappa opioid receptor.</p>Fórmula:C27H29N5O3Cor e Forma:SolidPeso molecular:471.551(±)-J 113397
CAS:<p>(±)-J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K(i): cloned human ORL1=1.8 nM).</p>Fórmula:C24H37N3O2Cor e Forma:SolidPeso molecular:399.57SB-612111 hydrochloride
<p>SB-612111 is a potent ORL-1 antagonist, with high affinity (Ki: 0.33 nM) and µ-receptor activity (Ki: 57.6 nM), blocking Nociceptin-induced pain.</p>Fórmula:C24H30Cl3NOCor e Forma:SolidPeso molecular:454.86KNT-127
CAS:<p>KNT-127 is an agonist of δ-Opioid receptor.</p>Fórmula:C24H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:372.46Mu opioid receptor antagonist 5
<p>Compound NAP: MOR antagonist, crosses blood-brain barrier, EC50: 1.14 nM, Ki: 0.37 nM, useful for OUD research.</p>Fórmula:C26H29N3O4Cor e Forma:SolidPeso molecular:447.53
