Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 330 produtos para "Receptor opioide".
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BAM-22P
CAS:Bovine adrenal medulla docosapeptide (BAM-22P) is a potent opioid agonist, derived from the proenkephalin A gene, which is present in the adrenal medulla.Fórmula:C130H184N38O31S2Pureza:98%Cor e Forma:SolidPeso molecular:2839.22TAN67
CAS:TAN67 is the first effective selective non-peptide delta1 opioid receptor.Fórmula:C23H26Br2N2OCor e Forma:SolidPeso molecular:506.282N-Acetyl-α-Endorphin
CAS:N-Acetyl-α-Endorphin is a chemical compound consisting of α-Endorphin that has been acetylated at the N-terminal.Fórmula:C79H122N18O27SPureza:98%Cor e Forma:SolidPeso molecular:1787.98D-Ala-Gly-Phe-Met-NH2 monoacetate
CAS:D-Ala-Gly-Phe-Met-NH2 monoacetate, an opioid peptide, serves as a potent agonist for the opiate δ-receptor [1].Fórmula:C21H33N5O6SCor e Forma:SolidPeso molecular:483.58Ac-RYYRIK-NH2
CAS:NOP site high affinity ligand (Ki=1.5 nM); blocks nociceptin effects in rat brain/heart; agonist in vivo, reduces mouse movement.Fórmula:C44H70N14O9Pureza:98%Cor e Forma:SolidPeso molecular:939.12(Rac)-SNC80
CAS:(Rac)-SNC80, a racemic δ-opioid agonist (K i 1.78 nM), shows potential for treating various headache disorders.Fórmula:C28H39N3O2Cor e Forma:SolidPeso molecular:449.63Kentsin
CAS:Kentsin, as a contraceptive polypeptide, has central opiate properties on gastrointestinal motility.Fórmula:C21H40N8O6Cor e Forma:SolidPeso molecular:500.59(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
CAS:E-2078, known chemically as (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8), is a stable analog of Dynorphin A (1–8) and functions as a kappa opioidFórmula:C50H81N15O9Cor e Forma:SolidPeso molecular:1036.27Ac-RYYRWK-NH2
CAS:Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.Fórmula:C49H69N15O9Pureza:98%Cor e Forma:SolidPeso molecular:1012.17[Nphe1]Nociceptin(1-13)NH2 TFA
[Nphe1]Nociceptin(1-13)NH2 is a selective nociceptin receptor antagonist with potential analgesic properties, pKi=8.4, pA2=6.0.Fórmula:C63H101F3N22O17Cor e Forma:SolidPeso molecular:1495.61Nocistatin
CAS:Nocistatin, a neuropeptide, blocks Nociceptin effects and inhibits 5-HT release, acting on an opioid-related receptor.Fórmula:C32H56N10O12Cor e Forma:SolidPeso molecular:772.85Naldemedine
CAS:Naldemedine (S 297995), developed by Shionogi, is a drug for opioid side effects like constipation. It's well tolerated with minor GI issues.Fórmula:C32H34N4O6Cor e Forma:SolidPeso molecular:570.64PIPE-3297
PIPE-3297 (compound 25) is a selective kappa opioid receptor (KOR) agonist that activates the G protein signaling pathway with an EC50 of 1.1 nM and exhibits low β-arrestin-2 recruitment activity (10%). Additionally, PIPE-3297 promotes myelination and has anti-inflammatory properties.Fórmula:C23H30N2OCor e Forma:SolidPeso molecular:350.23581Dynorphin A (1-13) amide
CAS:Dynorphin A (1-13) amide, an endogenous opioid peptide, counteracts the analgesic effects of morphine [1].Fórmula:C75H127N25O14Cor e Forma:SolidPeso molecular:1602.97Axelopran
CAS:Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.Fórmula:C26H39N3O4Cor e Forma:SolidPeso molecular:457.61α-Neoendorphin (1-8)
CAS:α-Neoendorphin (1-8) is a 8-amino acid peptide derived from the N-terminal of α-Neoendorphin.Fórmula:C49H70N12O11Pureza:98%Cor e Forma:SolidPeso molecular:1003.15DAMGO (TFA)
CAS:DAMGO is a selective peptide agonist of the µ-opioid receptor .Fórmula:C28H36F3N5O8Pureza:98%Cor e Forma:SolidPeso molecular:627.61[Arg14,Lys15]Nociceptin
CAS:Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.Fórmula:C82H137N31O22Pureza:98%Cor e Forma:SolidPeso molecular:1909.18[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Fórmula:C65H107N21O15Pureza:99.59%Cor e Forma:SolidPeso molecular:1422.7β-Endorphin (1-27) (human)
CAS:β-Endorphin (1-27) (human) is an opioid antagonist that selectively binds to μ-, δ-, and κ-opioid receptors, with dissociation constants (Kis) of 5.31, 6.17,Fórmula:C139H217N33O40SPureza:98%Cor e Forma:SolidPeso molecular:3022.47
![[Arg14,Lys15]Nociceptin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1986.webp&w=3840&q=75)
![[DPro10] Dynorphin A (1-11)acetate,porcine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76341L.webp&w=3840&q=75)
