Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 297 produtos de "Receptor opioide"
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Leumorphin, human
CAS:<p>Leumorphin, human, is a potent agonist of the kappa opioid receptor (κ opioid receptor) and inhibits the contraction of the guinea pig ileum's myenteric plexus-</p>Fórmula:C150H224N42O46Pureza:98%Cor e Forma:SolidPeso molecular:3351.64Deltorphin acetate
<p>Deltorphin acetate is a substance obtained from the skin secretions of a frog, Phyllomedusa bicolor and shows high selectivity and affinity for δ-opioid</p>Fórmula:C46H66N10O12S2Pureza:98.93%Cor e Forma:SolidPeso molecular:1015.21CJ-15208
CAS:<p>CJ-15208: κ-opioid antagonist, IC50: 47 nM kappa, 260 nM mu, 2600 nM delta, reverses asimadoline effects in rabbits (ED50 1.3 µM).</p>Fórmula:C34H35N5O4Cor e Forma:SolidPeso molecular:577.67N-terminally acetylated Endomorphin-1
<p>N-terminally acetylated Endomorphin-1 is a modified Endomorphin-1.</p>Fórmula:C36H40N6O6Pureza:98%Cor e Forma:SolidPeso molecular:652.74N-Acetyl-α-Endorphin
CAS:N-Acetyl-α-Endorphin is a chemical compound consisting of α-Endorphin that has been acetylated at the N-terminal.Fórmula:C79H122N18O27SPureza:98%Cor e Forma:SolidPeso molecular:1787.98Opioid receptor agonist 1
<p>Opioid receptor agonist1 (Compound 2638-28) is an orally active opioid receptor agonist that shows strong affinity for MOR, DOR, and KOR, with Ki values of 5, 24, and 212 nM, respectively. It exhibits analgesic activity in both the mouse warm water tail-flick model and the acetic acid writhing model.</p>Fórmula:C32H45N5OCor e Forma:SolidPeso molecular:515.73Neuropeptide AF (human) acetate
<p>Neuropeptide AF (human) acetate (Neuropeptide AF (human) acetate (192387-38-5 Free base)) is an anti-opioid neuropeptide, a Neuropeptide AF (human) derivative,</p>Pureza:99.89%Cor e Forma:SoildCTOP acetate
<p>CTOP acetate is a somatostatin analogue and a μ-opioid receptor antagonist.</p>Fórmula:C52H71N11O13S2Pureza:99.87%Cor e Forma:SoildPeso molecular:1122.32UFP-101 acetate
<p>UFP-101 acetate is a selective and competitive antagonist of the NOP receptor (pKi = 10.24) with >3000-fold selectivity over δ, μ, and κ opioid receptors.</p>Fórmula:C84H142N32O23Pureza:95.92%Cor e Forma:SolidPeso molecular:1968.23difelikefalin acetate(1024828-77-0 Free base)
CAS:<p>is a ketone and a building block.</p>Fórmula:C38H57N7O8Pureza:96.94%Cor e Forma:SolidPeso molecular:739.9[(pF)Phe4]Nociceptin(1-13)NH2 acetate
<p>[(pF)Phe4]Nociceptin(1-13)NH2 acetate is a selective agonist of NOP receptor with a pKi of 10.68 and a pEC50 of 9.31.</p>Fórmula:C63H103FN22O17Pureza:98.03%Cor e Forma:SolidPeso molecular:1459.63[D-Ala2]leucine-enkephalin acetate
<p>[D-Ala2]leucine-enkephalin acetate ([D-Ala2]leucine-enkephalin acetate (64963-01-5 free base)) is a delta opioid agonist used to study the signaling pathway of</p>Fórmula:C31H43N5O9Pureza:98%Cor e Forma:SolidPeso molecular:629.65β-Endorphin (1-27) (human) acetate
<p>β-Endorphin (1-27) (human) acetate, existing in the hypophysis cerebri and hypothalamus, exhibits antinociception activity.</p>Fórmula:C141H221N33O42SPureza:96.52%Cor e Forma:SolidPeso molecular:3082.52β-Endorphin (6-31), human
CAS:<p>β-Endorphin is an endogenous opioid neuropeptide and opioid receptor agonist that preferentially binds to μ-opioid receptors.</p>Fórmula:C131H218N34O40Pureza:98%Cor e Forma:SolidPeso molecular:2909.38Deltorphin
CAS:<p>Deltorphin (Dermenkephalin) is Isolated from the skin of Phyllomedusa Sauvage. It also has an affinity to the opioid receptor.</p>Fórmula:C44H62N10O10S2Pureza:98.96%Cor e Forma:SolidPeso molecular:955.15Porcine dynorphin A(1-13)
CAS:Porcine dynorphin A (1-13) is a potent κ opioid receptor agonist; it's antinociceptive and raises [Ca2+]i in neurons like NMDA.Fórmula:C75H126N24O15Pureza:98%Cor e Forma:SolidPeso molecular:1603.95Loperamide phenyl
CAS:<p>Loperamide phenyl, an impurity detected in Loperamide, is an opioid receptor agonist.</p>Fórmula:C35H37ClN2O2Cor e Forma:SolidPeso molecular:553.14Endomorphin 2 TFA
CAS:<p>Endomorphin 2 TFA, displays reasonable affinities for kappa3 binding sites, with Ki value between 20 and 30 nM.</p>Fórmula:C34H38F3N5O7Cor e Forma:SolidPeso molecular:685.69BMS-986121
CAS:<p>BMS-986121 is a selective positive allosteric modulator (PAM) of the μ opioid receptor with analgesic effects.</p>Fórmula:C15H9Cl2N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:366.22[Leu5]-Enkephalin
CAS:<p>[Leu5]-Enkephalin (Leu-enkephalin) is an endogenous neuropeptide involved in nociception and an agonist of δ-opioid and μ-opioid receptors (Kis = 4.0 and 3.4 nM</p>Fórmula:C28H37N5O7Pureza:99.87% - 99.88%Cor e Forma:SolidPeso molecular:555.62Alvimopan dihydrate (LY246736 dihydrate)
CAS:<p>Alvimopan dihydrate is a potent, oral μ-opioid receptor blocker (IC50 1.7 nM, Ki 0.47 nM) used in postoperative ileus research.</p>Fórmula:C25H36N2O6Cor e Forma:SolidPeso molecular:460.56Asimadoline
CAS:Asimadoline (EMD-61753) is a proprietary small molecule therapeutic, originally discovered by Merck KGaA of Darmstadt, Germany.Fórmula:C27H30N2O2Cor e Forma:SolidPeso molecular:414.54BAN ORL 24 dihydrochloride
CAS:<p>BAN ORL 24 dihydrochloride is a highly potent nociceptin/orphan FQ (N/OFQ) receptor (NOP) antagonist that can be used to study neurological diseases.</p>Fórmula:C27H37Cl2N3O2Pureza:95.03%Cor e Forma:SolidPeso molecular:506.51Dermorphin TFA
CAS:<p>Dermorphin TFA is a new class of opioids-like peptides</p>Fórmula:C42H51F3N8O12Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:916.89Deltorphin I
CAS:<p>Deltorphin I is an agonist of δ-opioid receptor.</p>Fórmula:C37H52N8O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:768.86Sec-O-Glucosylhamaudol
CAS:<p>Sec-O-Glucosylhamaudol has anti-inflammatory and strong antinociceptive properties, acting on p38 MAPK and opioid receptors.</p>Fórmula:C21H26O10Pureza:99.79%Cor e Forma:SolidPeso molecular:438.43BRL 52537 hydrochloride
CAS:<p>BRL 52537 hydrochloride: selective KOR agonist, may protect against ischemic brain injury, used in stroke and heart attack research.</p>Fórmula:C18H25Cl3N2OPureza:99.04%Cor e Forma:SolidPeso molecular:391.76DPDPE TFA (88373-73-3 free base)
CAS:<p>DPDPE TFA is selective δ-opioid receptor agonist peptide. DPDPE TFA has an analgesic effect and is antinociceptive in vivo.</p>Fórmula:C32H40F3N5O9S2Pureza:99.39%Cor e Forma:SolidPeso molecular:759.81Nociceptin (1-7) acetate
<p>Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor.</p>Fórmula:C31H41N7O9Pureza:98.92%Cor e Forma:SoildPeso molecular:655.7Aticaprant
CAS:<p>Aticaprant (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).Cost-effective and quality-assured.</p>Fórmula:C26H27FN2O2Pureza:99.53% - 99.93%Cor e Forma:SolidPeso molecular:418.5BMS986187
CAS:<p>BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.</p>Fórmula:C31H34O4Pureza:99.09%Cor e Forma:SolidPeso molecular:470.6Ac-RYYRIK-NH2 acetate
<p>Ac-RYYRIK-NH2 acetate is an agonist at nociceptin/orphanin FQ(noc/OFQ) receptors, affecting spontaneous locomotor activity.</p>Fórmula:C46H74N14O11Pureza:99.84%Cor e Forma:SolidPeso molecular:999.17[Met5]-Enkephalin, amide TFA
<p>[Met5]-Enkephalin, amide TFA (5-Methionine-enkephalin amide (TFA)) is a δ opioid receptors agonist as well as putative ζ (zeta) opioid receptors.</p>Fórmula:C29H37F3N6O8SPureza:99.81%Cor e Forma:SolidPeso molecular:686.7LY2940094 tartrate
CAS:<p>LY-2940094, a nociceptin receptor antagonist, is used potentially for the treatment of major depressive disorder and alcoholism.</p>Fórmula:C26H29ClF2N4O8SCor e Forma:SolidPeso molecular:631.04MCOPPB triHydrochloride
CAS:<p>MCOPPB triHydrochloride (MCOPPB 3HCl) is a nociceptin receptor agonist.</p>Fórmula:C26H43Cl3N4Pureza:99.89% - 99.91%Cor e Forma:SolidPeso molecular:518.01Salvinorin A
CAS:<p>Salvinorin A is a non-nitrogenous κ-opioid selective agonist.</p>Fórmula:C23H28O8Pureza:99.06%Cor e Forma:SolidPeso molecular:432.46Naloxegol oxalate
CAS:<p>Naloxegol oxalate (NKTR-118) is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation.</p>Fórmula:C36H55NO15Pureza:99.67% - >99.99%Cor e Forma:SolidPeso molecular:741.83Ac-RYYRWK-NH2 acetate
<p>Ac-RYYRWK-NH2 acetate is a potent partial agonist of the nociceptin receptor(NOP), which is the endogenous ORL1 receptor agonist.</p>Fórmula:C51H73N15O11Pureza:98.59%Cor e Forma:SolidPeso molecular:1072.22Nalmefene hydrochloride
CAS:<p>Nalmefene antagonizes the effects of opioids by competing for the opioid receptors in the CNS.</p>Fórmula:C21H26ClNO3Pureza:98% - 99.85%Cor e Forma:SolidPeso molecular:375.89Difelikefalin acetate
CAS:<p>Difelikefalin acetate (CR 845 acetate) is a peripherally restricted kappa opioid receptor agonist.</p>Fórmula:C38H57N7O8Pureza:99.55%Cor e Forma:SolidPeso molecular:739.9AR-M 1000390 hydrochloride
CAS:<p>ARM-390 HCl is a δ-opioid receptor agonist, brain-penetrant, nonpeptidic, prevents hyperalgesia without desensitization. Derived from SNC 80.</p>Fórmula:C23H29ClN2OPureza:98.66%Cor e Forma:SolidPeso molecular:384.94Tyr-Gly-Gly-Phe-Met-OH
CAS:<p>Tyr-Gly-Gly-Phe-Met-OH (Met-Enkephalin), is a naturally occurring, endogenous opioid peptide that inhibits tumor growth via binding to the opioid receptor.</p>Fórmula:C27H35N5O7SPureza:≥95%Cor e Forma:White Lyophilised SolidPeso molecular:573.66b-Casomorphin (1-3) Acetate
<p>b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.</p>Fórmula:C25H31N3O7Pureza:98.99%Cor e Forma:SolidPeso molecular:485.53Endomorphin 2
CAS:<p>EM-2 reduces sEPSC frequency/amplitude in lamina IX motoneurons; CTOP reverses this. EM-2-IR affects limb muscles via presynaptic/postsynaptic mechanisms.</p>Fórmula:C32H37N5O5Pureza:99.64%Cor e Forma:SolidPeso molecular:571.67Methylnaltrexone bromide
CAS:Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists, acts to reverse the side effects of opioid drugs.Fórmula:C21H26BrNO4Pureza:99.02%Cor e Forma:SolidPeso molecular:436.35EST73502 HCl
CAS:<p>EST73502 is an agonist of μ-opioid receptor(Ki = 64 nM) agonist and an antagonist of σ1 receptor (Ki = 118 nM). EST73502 displays antinociceptive activity.</p>Fórmula:C19H27ClF2N2O2Pureza:99.96%Cor e Forma:SolidPeso molecular:388.88JTC-801
CAS:<p>JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.</p>Fórmula:C26H25N3O2·HClPureza:99.27% - 99.59%Cor e Forma:SolidPeso molecular:447.96BAM 22P acetate
<p>BAM 22P acetate is a potent opioid agonist.</p>Fórmula:C132H188N38O33S2Pureza:99.87%Cor e Forma:SoildPeso molecular:2899.27BMS-986122
CAS:<p>BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1</p>Fórmula:C16H15BrClNO3S2Pureza:98.42%Cor e Forma:SolidPeso molecular:448.78ADL-5859
CAS:<p>ADL-5859 (ADL5859 Hydrochloride) is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for the</p>Fórmula:C24H28N2O3·HClPureza:98.78% - 99.11%Cor e Forma:SolidPeso molecular:428.95
![[(pF)Phe4]Nociceptin(1-13)NH2 acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1885L1.webp&w=3840&q=75)
![[D-Ala2]leucine-enkephalin acetate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1367L.webp&w=3840&q=75)
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