Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 330 produtos para "Receptor opioide".
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Sec-O-Glucosylhamaudol
CAS:Sec-O-Glucosylhamaudol has anti-inflammatory and strong antinociceptive properties, acting on p38 MAPK and opioid receptors.Fórmula:C21H26O10Pureza:99.79%Cor e Forma:SolidPeso molecular:438.43Naloxegol (NKTR-118)
CAS:Naloxegol (NKTR-118; AZ-13337019) is an opioid-receptor antagonist[1].Fórmula:C34H53NO11Cor e Forma:SolidPeso molecular:651.78DAMGO TFA (78123-71-4(Free base))
DAMGO TFA (78123-71-4(Free base)) is a potent and selective agonist of the Mu-opioid receptor.Cost-effective and quality-assured.Fórmula:C28H36F3N5O8Pureza:98.67% - 99.76%Cor e Forma:SolidPeso molecular:627.6Endomorphin 2
CAS:EM-2 reduces sEPSC frequency/amplitude in lamina IX motoneurons; CTOP reverses this. EM-2-IR affects limb muscles via presynaptic/postsynaptic mechanisms.Fórmula:C32H37N5O5Pureza:99.64%Cor e Forma:SolidPeso molecular:571.67Orphanin FQ(1-11) acetate(178249-41-7 free base)
Nociceptin peptide fragment (1-11 aa), potent ORL1/KOR-3 agonist (Ki=55 nM), non-opioid, analgesic in mice.Fórmula:C51H79N15O16Pureza:99.94%Cor e Forma:SolidPeso molecular:1158.26EST73502 HCl
CAS:EST73502 is an agonist of μ-opioid receptor(Ki = 64 nM) agonist and an antagonist of σ1 receptor (Ki = 118 nM). EST73502 displays antinociceptive activity.Fórmula:C19H27ClF2N2O2Pureza:99.96%Cor e Forma:White SolidPeso molecular:388.88Ref: TM-T39284
1mg96,00€5mg172,00€1mL*10mM (DMSO)187,00€10mg244,00€25mg403,00€50mg567,00€100mg750,00€200mg1.018,00€JTC-801
CAS:JTC-801 is a selective opioid receptor-like1 (ORL1) receptor antagonist with IC50 of 94 nM, weakly inhibits receptors δ, κ, and μ.Fórmula:C26H25N3O2·HClPureza:99.27% - 99.59%Cor e Forma:SolidPeso molecular:447.96Alvimopan monohydrate
CAS:Alvimopan monohydrate is a mu-opioid receptor antagonist that intended for the treatment of constipation in patients who take opiates for pain.Fórmula:C25H34N2O5Pureza:98%Cor e Forma:SolidPeso molecular:442.55AR-M 1000390 hydrochloride
CAS:ARM-390 HCl is a δ-opioid receptor agonist, brain-penetrant, nonpeptidic, prevents hyperalgesia without desensitization. Derived from SNC 80.Fórmula:C23H29ClN2OPureza:98.66%Cor e Forma:SolidPeso molecular:384.94BMS-986122
CAS:BMS-986122 (BMS 986122) is a positive allosteric modulator of μ-opioid receptors that increases β-arrestin recruitment stimulated by endomorphin 1 in U2OS-OPRM1Fórmula:C16H15BrClNO3S2Pureza:98.42%Cor e Forma:SolidPeso molecular:448.78Ref: TM-T26869
1mg46,00€5mg90,00€1mL*10mM (DMSO)90,00€10mg152,00€25mg295,00€50mg447,00€100mg623,00€200mg880,00€Leuphasyl TFA
CAS:Leuphasyl TFA: a long-lasting, degradation-resistant peptide & δ-opioid receptor agonist for signaling research.Fórmula:C31H40F3N5O9Pureza:98.79%Cor e Forma:SolidPeso molecular:683.67Deltorphin I
CAS:Deltorphin I is an agonist of δ-opioid receptor.Fórmula:C37H52N8O10Pureza:>99.99%Cor e Forma:White SolidPeso molecular:768.86Nociceptin (1-7) acetate
Nociceptin (1-7) acetate is a potent agonist of opioid receptor-like 1 (ORL1) receptor.Fórmula:C31H41N7O9Pureza:98.92%Cor e Forma:White SolidPeso molecular:655.7Ref: TM-T23076L
1mg294,00€2mg439,00€5mg660,00€1mL*10mM (DMSO)897,00€10mg999,00€25mg1.468,00€50mg1.998,00€100mg2.692,00€[Leu5]-Enkephalin, amide acetate
[Leu5]-Enkephalin, amide acetate is a δ opioid receptor agonist.Fórmula:C30H42N6O8Pureza:99.95%Cor e Forma:White SolidPeso molecular:614.69Dynorphin A 1-10 acetate(79994-24-4 free base)
Dynorphin A (1-10) acetate is an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor.Fórmula:C59H95N19O14Pureza:97.17%Cor e Forma:White SolidPeso molecular:1294.53[Met5]-Enkephalin, amide TFA
[Met5]-Enkephalin, amide TFA (5-Methionine-enkephalin amide (TFA)) is a δ opioid receptors agonist as well as putative ζ (zeta) opioid receptors.Fórmula:C29H37F3N6O8SPureza:99.81%Cor e Forma:White SolidPeso molecular:686.7Ac-RYYRIK-NH2 acetate
Ac-RYYRIK-NH2 acetate is an agonist at nociceptin/orphanin FQ(noc/OFQ) receptors, affecting spontaneous locomotor activity.Fórmula:C46H74N14O11Pureza:99.76%Cor e Forma:SolidPeso molecular:999.17Hemorphin-7 acetate(152685-85-3 free base)
Hemorphin-7 acetate is a hemorphin peptide, an endogenous opioid peptide derived from the β-chain of hemoglobin.Fórmula:C51H68N12O13Pureza:99.75%Cor e Forma:SolidPeso molecular:1057.16Nociceptin (1-13) amide TFA
Nociceptin (1-13), amide: ORL1 receptor agonist, pEC50 7.9 (mouse vas deferens), Ki 0.75 nM (rat forebrain binding).Fórmula:C63H101F3N22O17Pureza:97.64%Cor e Forma:SolidPeso molecular:1495.61Sinomenine
CAS:Sinomenine (Kukoline) is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.Fórmula:C19H23NO4Pureza:99.02% - 99.73%Cor e Forma:White SolidPeso molecular:329.39Nociceptin
CAS:Nociceptin (Orphanin FQ) is a 17-amino-acid polypeptide that is structurally related to the opioid peptide dynorphin A.Fórmula:C79H129N27O22Pureza:99.35%Cor e Forma:SolidPeso molecular:1809.04Nalmefene hydrochloride
CAS:Nalmefene antagonizes the effects of opioids by competing for the opioid receptors in the CNS.Fórmula:C21H26ClNO3Pureza:98% - 99.85%Cor e Forma:SolidPeso molecular:375.89Aticaprant
CAS:Aticaprant (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).Cost-effective and quality-assured.Fórmula:C26H27FN2O2Pureza:99.80% - 99.97%Cor e Forma:SolidPeso molecular:418.5Ref: TM-TQ0082
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg119,00€25mg245,00€50mg385,00€100mg575,00€[D-Ala2]leucine-enkephalin
CAS:[D-Ala2]-Leucine enkephalin is a delta opioid agonist used to study the signaling pathway of delta opioid receptors.Fórmula:C29H39N5O7Pureza:98.06%Cor e Forma:White SolidPeso molecular:569.65Naloxegol oxalate
CAS:Naloxegol oxalate (NKTR-118) is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation.Fórmula:C36H55NO15Pureza:99.67% - >99.99%Cor e Forma:SolidPeso molecular:741.83Deltorphin 2
CAS:Deltorphin 2 ([D-Ala2]-Deltorphin II) is an agonist of δ opioid receptor with an IC50 of 1 nM.Fórmula:C38H54N8O10Pureza:>99.99%Cor e Forma:SolidPeso molecular:782.88Adrenorphin 3TFA(88377-68-8(free base))
Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) is an agonist of μ-opioid receptor(Ki :12 nM).Fórmula:C50H72N15O15SPureza:>99.99%Cor e Forma:SolidPeso molecular:1326.26Asimadoline hydrochloride
CAS:Asimadoline HCl (EMD-61753) is a kappa-opioid receptor agonist for pruritus and IBS treatment.Fórmula:C27H31ClN2O2Pureza:98.94% - 99.32%Cor e Forma:SolidPeso molecular:451.01Ref: TM-T4691
1mg34,00€5mg70,00€1mL*10mM (DMSO)77,00€10mg105,00€25mg215,00€50mg319,00€100mg474,00€500mg1.018,00€GR103545
CAS:GR103545 is a selective agonist of the κ-opioid receptor, which is a radiotracer that can be used as in vivo imaging.Fórmula:C23H29Cl2N3O7Pureza:99.75%Cor e Forma:SolidPeso molecular:530.4Ref: TM-T9459
1mg93,00€2mg136,00€5mg178,00€1mL*10mM (DMSO)236,00€10mg268,00€25mg482,00€50mg688,00€100mg964,00€ADL-5859
CAS:ADL-5859 HCl is a selective δ-opioid receptor agonist ( Ki: 0.8 nM), selectivity against opioid receptor κ, μ, and little inhibition for theFórmula:C24H28N2O3·HClPureza:98.78% - 99.11%Cor e Forma:White SolidPeso molecular:428.95Ref: TM-T6175
1mg49,00€2mg66,00€5mg90,00€1mL*10mM (DMSO)108,00€10mg166,00€25mg319,00€50mg492,00€100mg710,00€500mg1.468,00€Dynorphin A acetate(80448-90-4 free base)
Dynorphin A acetate is an Endogenous kappa receptor agonist.Fórmula:C101H159N31O25Pureza:99.94%Cor e Forma:SolidPeso molecular:2207.58Endomorphin 1
CAS:Endomorphin 1 is a high affinity and selective agonist of the μ-opioid receptor and displays reasonable affinities for kappa3 binding sites (Ki: 20~30 nM).Fórmula:C34H38N6O5Pureza:95.92%Cor e Forma:SolidPeso molecular:610.7b-Casomorphin (1-3) Acetate
b-Casomorphin (1-3) Acetate is a tri-peptide with an opioid effect.Fórmula:C25H31N3O7Pureza:98.99%Cor e Forma:SolidPeso molecular:485.53Ref: TM-T21660L
5mg42,00€1mL*10mM (DMSO)55,00€10mg57,00€25mg87,00€50mg131,00€100mg190,00€200mg285,00€MCOPPB
CAS:MCOPPB: potent, selective nociceptin receptor agonist, pKi 10.07, minor opioid activity, anxiolytic in animals, non-sedative.Fórmula:C26H40N4Cor e Forma:SolidPeso molecular:408.62MCOPPB triHydrochloride
CAS:MCOPPB triHydrochloride (MCOPPB 3HCl) is a nociceptin receptor agonist.Fórmula:C26H43Cl3N4Pureza:99.89% - 99.91%Cor e Forma:SolidPeso molecular:518.01Ref: TM-T2071
2mg33,00€5mg52,00€1mL*10mM (DMSO)55,00€10mg82,00€25mg155,00€50mg241,00€100mg355,00€200mg507,00€BAM 22P acetate
BAM 22P acetate is a potent opioid agonist.Fórmula:C132H188N38O33S2Pureza:99.83%Cor e Forma:White SolidPeso molecular:2899.27Ref: TM-TP1211L
1mg100,00€5mg376,00€10mg565,00€25mg1.009,00€50mg1.359,00€100mg1.845,00€200mg2.485,00€BRL 52537 hydrochloride
CAS:BRL 52537 hydrochloride: selective KOR agonist, may protect against ischemic brain injury, used in stroke and heart attack research.Fórmula:C18H25Cl3N2OPureza:99.61%Cor e Forma:SolidPeso molecular:391.76LY2940094 tartrate
CAS:LY-2940094, a nociceptin receptor antagonist, is used potentially for the treatment of major depressive disorder and alcoholism.Fórmula:C26H29ClF2N4O8SCor e Forma:SolidPeso molecular:631.04CTAP(TFA) (103429-32-9 free base)
CTAP(TFA) (103429-32-9 free base) is a potent, highly selective, and brain-penetrant antagonist of the μ-opioid receptor with IC50 of 3.5 nM.Fórmula:C53H70F3N13O13S2Pureza:99.62%Cor e Forma:SolidPeso molecular:1218.33ADL-5747 (HCl)
CAS:ADL-5747, an opioid delta receptor agonist, is used potentially for the treatment of pain.Fórmula:C24H29ClN2O3Cor e Forma:SolidPeso molecular:428.95PZM21
CAS:PZM21 is an effective and selective μ opioid receptor agonist (EC50: 1.8 nM).Fórmula:C19H27N3O2SPureza:99.93% - >99.99%Cor e Forma:White SolidPeso molecular:361.5Ref: TM-T4386
1mg44,00€2mg57,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg120,00€25mg193,00€50mg281,00€100mg447,00€Ac-RYYRWK-NH2 acetate
Ac-RYYRWK-NH2 acetate is a potent partial agonist of the nociceptin receptor(NOP), which is the endogenous ORL1 receptor agonist.Fórmula:C51H73N15O11Pureza:99.91%Cor e Forma:SolidPeso molecular:1072.22EST73502 hydrochloride
CAS:EST73502 HCl is an oral dual MOR agonist/σ1R antagonist, BBB-penetrant, Ki: 64 nM (MOR), 118 nM (σ1R), with antinociceptive properties.Fórmula:C19H27ClF2N2O2Cor e Forma:SolidPeso molecular:388.88Dynorphin B (1-13) acetate(83335-41-5 free base)
Dynorphin B (1-13) acetate acts as an agonist on opioid κ-receptor.Fórmula:C76H119N21O19Pureza:99.72%Cor e Forma:SolidPeso molecular:1630.89Methylnaltrexone bromide
CAS:Methylnaltrexone bromide (MOA-728) is one of the newer agents of peripherally-acting μ-opioid antagonists, acts to reverse the side effects of opioid drugs.Fórmula:C21H26BrNO4Pureza:99.02%Cor e Forma:SolidPeso molecular:436.35Porcine dynorphin A(1-13) acetate
Porcine dynorphin A(1-13) acetate is a potent κ-opioid agonist with antinociceptive properties, increasing [Ca2+]i like NMDA.Fórmula:C77H130N24O17Pureza:98.43%Cor e Forma:SolidPeso molecular:1664Corydaline
CAS:Corydaline: an isoquinoline alkaloid that aids digestion, has anti-inflammatory and pain relief properties, and inhibits CYP2C19 and CYP2C9.Fórmula:C22H27NO4Pureza:98.97% - 99.86%Cor e Forma:Yellow SolidPeso molecular:369.45BMS986187
CAS:BMS986187 is a novel Potent and Selective Positive Allosteric Modulators of the delta-Opioid Receptor.Fórmula:C31H34O4Pureza:99.09%Cor e Forma:SolidPeso molecular:470.6Bisacodyl
CAS:Bisacodyl (Fenilaxan) is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation.Fórmula:C22H19NO4Pureza:99.45% - 99.90%Cor e Forma:White SolidPeso molecular:361.39GR 89696 free base
CAS:GR 89696 free base is a potent κ2 opioid receptor agonist with a high selectivity, offering potential benefits in pruritus prevention.Fórmula:C19H25Cl2N3O3Cor e Forma:SolidPeso molecular:414.33
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