Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 330 produtos para "Receptor opioide".
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
(D-Ser2)-Leu-Enkephalin-Thr
(D-Ser2)-Leu-Enkephalin-Thr is a delta selective agent of opioid receptor and shows analgesic effects.Fórmula:C33H46N6O10Pureza:94.17%Cor e Forma:SolidPeso molecular:686.75GRT2932Q
CAS:GRT2932Q is a nonpeptidic agonist of the opioid receptor-like 1 (ORL1) [1].Fórmula:C25H26ClN3OCor e Forma:SolidPeso molecular:419.95AH 7959
CAS:AH 7959 is an orally active N-substituted cyclohexylmethylbenzamide compound that exhibits analgesic properties. In mice, the ED50 for oral and subcutaneous administration of AH 7959 exceeds 100 mg/kg.Fórmula:C19H26Cl2N2OCor e Forma:SolidPeso molecular:369.33Fluorphine
CAS:Fluorphine, an analog of Brorphine, binds to the μ-opioid receptor (MOR) with a Ki of 12.5 nM. It exhibits GTPγS binding activity with an EC50 of 75 nM and β-arrestin 2 recruitment activity with an EC50 of 377 nM, and it also has respiratory depressive effects.Fórmula:C20H22FN3OCor e Forma:SolidPeso molecular:339.41AH 8529
CAS:AH 8529 is an orally active opioid compound with analgesic properties.Fórmula:C16H23ClN2OCor e Forma:SolidPeso molecular:294.82U-48520
CAS:U-48520 is an agonist of the μ-opioid receptor (μ-opioid receptor) with an EC50 of 1561 nM.Fórmula:C16H23ClN2OCor e Forma:SolidPeso molecular:294.82Orphine
CAS:Orphine is an opioid compound that can amplify the antinociceptive effects reduced by naloxone in mice.Fórmula:C20H23N3OCor e Forma:SolidPeso molecular:321.42Piperidylthiambutene hydrochloride
CAS:Piperidylthiambutene hydrochloride is an opioid compound that exhibits analgesic effects in animal models.Fórmula:C17H22ClNS2Cor e Forma:SolidPeso molecular:339.95AH 7563
CAS:AH 7563 is structurally classified as an opioid compound with analgesic properties. In mice, its ED50 for pain relief was 15.3 mg/kg when administered orally in the Phenylquinone test, and 15.5 mg/kg when injected subcutaneously in the Hot plate test.Fórmula:C16H24N2OCor e Forma:SolidPeso molecular:260.38AH 8532
CAS:AH 8532 is an opioid compound with analgesic effects and is effective in inhibiting the quinone-induced writhing response in mice, with an oral ED50 of 16 mg/kg.Fórmula:C16H23ClN2OCor e Forma:SolidPeso molecular:294.82DIPPA hydrochloride
CAS:κ receptor antagonistFórmula:C22H24Cl3N3OSPureza:98%Cor e Forma:SolidPeso molecular:484.87TIPP
CAS:TIPP is an agent of delta opioid antagonist.Fórmula:C37H38N4O6Pureza:98%Cor e Forma:SolidPeso molecular:634.72BW 373U86
CAS:BW373U86 (SNC86), a δ-opioid receptor agonist, demonstrates potent activity with an IC50 value of 1.49 nM and has shown to exhibit antidepressant-like effects [Fórmula:C27H37N3O2Cor e Forma:SolidPeso molecular:435.6Endomorphin 1 acetate
CAS:Endomorphin 1 acetate is a μ-opioid receptor agonist with antinociceptive and analgesic effects and can be used to study neurological diseases.Fórmula:C36H42N6O7Pureza:99.74%Cor e Forma:White SolidPeso molecular:670.75CP-866087
CAS:CP-866087 is a novel, potent and selective mu-opioid receptor antagonist for the study of female sexual dysfunction.Fórmula:C24H28N2O2Pureza:99.56% - >99.99%Cor e Forma:White SolidPeso molecular:376.49LY 164929
CAS:LY 164929 is a highly selective ligand for the lower affinity [3H]D-Ala2-D-Leu-5-enkephalin binding site.Fórmula:C28H41N5O4Cor e Forma:SolidPeso molecular:511.66SR8993
CAS:SR8993 is a highly selective, brain-penetrant agonist of the nociceptin receptor.Fórmula:C25H37FN4Pureza:98%Cor e Forma:SolidPeso molecular:412.59BMS-986124
CAS:BMS-986124 is an allosteric modulator of the μ-Opioid Receptor.Fórmula:C16H15BrClNO3S2Cor e Forma:SolidPeso molecular:448.78DDD028
CAS:DDD-028 is a potential non-opioid and non-cannabinoid analgesic. It was used for treating neuropathic and inflammatory pain.Fórmula:C20H20N2Pureza:98%Cor e Forma:SolidPeso molecular:288.39PF-4455242 HCl
CAS:PF-4455242 HCl is a selective and orally available κ-opioid receptor antagonist that exhibiting antidepressant effects.Fórmula:C21H29ClN2O2SPureza:99.59%Cor e Forma:SolidPeso molecular:408.99Ici 174865
CAS:Ici 174865 is a delta opioid receptor antagonist agent.Fórmula:C38H53N5O7Cor e Forma:SolidPeso molecular:691.86Axomadol
CAS:Axomadol (EN3324) is a centrally active analgesic compound. It has opioid agonistic properties and inhibitory effects on the reuptake of monoamines.Fórmula:C16H25NO3Pureza:98%Cor e Forma:SolidPeso molecular:279.37Diallyl G
CAS:Diallyl G is a delta-opioid receptor antagonist agent.Fórmula:C38H53N5O8Cor e Forma:SolidPeso molecular:707.86Loperamide oxide
CAS:Loperamide oxide (R 58425) is a secreted antidiarrheal agent that increases peristalsis and inhibits intestinal absorption of water and ions.Fórmula:C29H33ClN2O3Cor e Forma:Yellow SolidPeso molecular:493.04CR-665 Acetate
CAS:CR-665, a kappa-opioid agonist, is used potentially for the treatment of postoperative pain.Fórmula:C38H53N9O6Cor e Forma:SolidPeso molecular:731.899AZD7268
CAS:AZD7268 is a potent, selective, reversible, and orally bioavailable agonist of δ-opioid receptor with CNS penetration.Fórmula:C29H30N4O2SCor e Forma:SolidPeso molecular:498.64AT-076
CAS:AT-076: κ-opioid (Ki=1.14 nM) & nociceptin (Ki=1.75 nM) noncompetitive antagonist; μ-opioid (Ki=1.67 nM) & δ-opioid (Ki=19.6 nM) competitive antagonist.Fórmula:C26H35N3O3Cor e Forma:SolidPeso molecular:437.57LY2048978
CAS:LY2048978: orally-active kappa antagonist, shows promise for mood and addiction in animal studies.Fórmula:C19H24N2O2Pureza:98%Cor e Forma:SolidPeso molecular:312.41Dup 747
CAS:Dup 747 is an analgesic that binds with high affinity and selectivity to the kappa-opioid receptor.Fórmula:C24H28Cl2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:447.4SCH 221510
CAS:SCH 221510: oral NOP agonist, EC50=12 nM, Ki=0.3 nM, anxiolytic, for neurological research.Fórmula:C28H31NOPureza:99.74%Cor e Forma:SolidPeso molecular:397.55LY2444296
CAS:LY2444296 (FP3FBZ) is an orally active and selective antagonist of kappa opioid receptor(Ki = 1 nM).Fórmula:C24H22F2N2O2Pureza:99.18%Cor e Forma:SolidPeso molecular:408.44Enadoline (Free Base)
CAS:Enadoline is a K-opioid agonist with visual and dissociative effects, studied for pain but dropped due to dysphoria.Fórmula:C24H32N2O3Cor e Forma:SolidPeso molecular:396.52Azoenkephalin
CAS:Azoenkephalin is the azo bridge between tyrosine & phenylalanine of enkephalin molecule.Fórmula:C28H35N7O7Cor e Forma:SolidPeso molecular:581.62ORL1 antagonist 1
CAS:ORL1 antagonist 1 is an o antagonist of pioid receptor-like 1 (ORL1) (IC50 of 61 nM).Fórmula:C20H22ClN5Pureza:98.92%Cor e Forma:SolidPeso molecular:367.88Ref: TM-T12320
1mg50,00€5mg105,00€1mL*10mM (DMSO)108,00€10mg155,00€25mg224,00€50mg315,00€100mg424,00€200mg560,00€GSK1521498 free base
CAS:GSK1521498 free base is an effective and selective μ-opioid receptor antagonist with potential applications in obesity, alcoholism, and drug addiction.Fórmula:C24H20F2N4Pureza:99.85%Cor e Forma:White SolidPeso molecular:402.44Ref: TM-T11478L
1mg109,00€5mg260,00€1mL*10mM (DMSO)286,00€10mg485,00€25mg945,00€50mg1.485,00€100mg2.250,00€Opioid receptor modulator 1
CAS:Opioid receptor modulator 1 is a modulator of opioid receptor.Fórmula:C18H23NO2Pureza:98%Cor e Forma:SolidPeso molecular:285.38GSK1521498
CAS:GSK1521498 is a selective antagonist of the μ-opioid receptor (MOR).Fórmula:C24H23F2N4O4PPureza:98%Cor e Forma:SolidPeso molecular:500.43ML 190
CAS:ML 190 is a potent and selective κ opioid receptor (KOR) antagonist (Ki=129 nM), exhibiting an IC50=150 nM in β-arrestin assays, drug addiction.Fórmula:C27H32N6O3Pureza:99.88%Cor e Forma:Yellow SolidPeso molecular:488.58Ref: TM-T22995
1mg63,00€5mg137,00€1mL*10mM (DMSO)147,00€10mg205,00€25mg447,00€50mg715,00€100mg964,00€Anrikefon
CAS:Anrikefon (HSK21542) is a kappa opioid receptor agonist with analgesic effect .Fórmula:C39H57N7O5Cor e Forma:SolidPeso molecular:703.91ADL-5859 HCl
CAS:ADL-5859 is a delta-opioid receptor agonist.Fórmula:C24H28N2O3Pureza:98%Cor e Forma:SolidPeso molecular:392.49GSK1521498 free base (hydrochloride)
CAS:GSK1521498 free base (hydrochloride) is a selective antagonist of the μ-opioid receptor (MOR).Fórmula:C24H21ClF2N4Pureza:98%Cor e Forma:SolidPeso molecular:438.9ICI 154,129
CAS:Selective δ opioid antagonistFórmula:C34H46N4O6SPureza:98%Cor e Forma:SolidPeso molecular:638.82JTC-801 free base
CAS:JTC-801 is a selective antagonist of the opioid receptor-like1 receptor (Ki: 8.2 nM).Fórmula:C26H25N3O2Pureza:98%Cor e Forma:SolidPeso molecular:411.5Viminol
CAS:Viminol is an opioid analgesic. Viminol is based on the α-pyrryl-2-aminoethanol structure, unlike any other class of opioids.Fórmula:C21H31ClN2OPureza:98%Cor e Forma:SolidPeso molecular:362.94LY 281217
CAS:LY 281217, an organic opioid agonist, can produce analgesic effects in mice.Fórmula:C32H42N4O6Pureza:98%Cor e Forma:SolidPeso molecular:578.7σ1 Receptor/μ Opioid receptor modulator 1
CAS:σ 1 Receptor/ μ Opioid receiver modulator 1 (Compound 44) is an effective σ 1 receptor antagonist (Ki=1.86 nM) and μ Opioid receptor agonists (Ki=2.1 nM).Fórmula:C24H31FN2O2Cor e Forma:SolidPeso molecular:398.51Norbinaltorphimine
CAS:nor-Binaltorphimine dihydrochloride is a long-acting potent and highly selective kappa opioid receptor antagonist.Fórmula:C40H43N3O6Cor e Forma:SolidPeso molecular:661.79ML138
CAS:ML138 is a probe for MLPCN, an agonist of the κ opioid receptor.Fórmula:C19H14Cl2N4OSCor e Forma:SolidPeso molecular:417.31μ opioid receptor agonist 2
CAS:μ opioid receptor agonist 2 （Compound H-3）is a MOR receptor agonist. μ opioid receptor agonist 2 can be used for the research of pain and pain related diseases.Fórmula:C25H34N4OCor e Forma:SolidPeso molecular:406.56ICI 204,448
CAS:ICI 204,448 is a potent κ-opioid agonist with potential analgesic activity for the study of neurological diseases.Fórmula:C23H27Cl3N2O4Pureza:>99.99%Cor e Forma:SolidPeso molecular:501.83
