Receptor LPA
Os receptores de ácido lisofosfatídico (LPA) são um grupo de GPCRs que respondem ao LPA, um lipídeo bioativo envolvido na proliferação, migração e sobrevivência celular. A sinalização do LPA desempenha um papel crucial em vários processos fisiológicos, incluindo cicatrização de feridas, desenvolvimento vascular e metástase do câncer. A modulação da atividade dos receptores de LPA está sendo explorada para aplicações terapêuticas em câncer, fibrose e doenças inflamatórias. Na CymitQuimica, oferecemos uma gama de moduladores de receptores de LPA de alta qualidade para apoiar sua pesquisa em sinalização celular, oncologia e distúrbios inflamatórios.
Foram encontrados 21 produtos de "Receptor LPA"
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AM095 free acid
CAS:AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1).Fórmula:C27H24N2O5Pureza:99.88%Cor e Forma:SolidPeso molecular:456.49Ref: TM-T10293
1mg34,00€5mg63,00€10mg92,00€25mg170,00€50mg268,00€100mg416,00€200mg625,00€1mL*10mM (DMSO)70,00€Ki16198
CAS:Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).Fórmula:C24H25ClN2O5SPureza:98.09%Cor e Forma:SolidPeso molecular:488.98ACT-1016-0707
CAS:ACT-1016-0707 is a selective, insurmountable LPA1 antagonist with antifibrotic and anti-inflammatory activity in lung fibrosis modelsFórmula:C19H23ClN4O4SPureza:99.905%Cor e Forma:SolidPeso molecular:438.93TAK-615
CAS:TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.Fórmula:C25H22FNO4Pureza:99.73%Cor e Forma:SolidPeso molecular:419.44Ref: TM-T9699
1mg72,00€5mg160,00€10mg245,00€25mg405,00€50mg572,00€100mg772,00€500mg1.539,00€1mL*10mM (DMSO)172,00€Edg-2 receptor inhibitor 1
CAS:Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).Fórmula:C27H27NO5Pureza:99.47%Cor e Forma:SolidPeso molecular:445.51Ref: TM-T4521
1mg97,00€2mg170,00€5mg274,00€10mg426,00€25mg663,00€50mg947,00€100mg1.264,00€1mL*10mM (DMSO)288,00€BMS-986020 sodium
CAS:BMS-986020 sodium (AM152 sodium) is a high-affinity LPA1 antagonist for investigating idiopathic pulmonary fibrosis.Fórmula:C29H25N2NaO5Pureza:99.83%Cor e Forma:SolidPeso molecular:504.51H2L 5765834
CAS:H2L 5765834 is a lysophosphatidic acid receptors antagonistFórmula:C21H12N2O7Pureza:98.25% - 99.47%Cor e Forma:SolidPeso molecular:404.33Ref: TM-T22834
1mg58,00€5mg113,00€10mg177,00€25mg334,00€50mg497,00€100mg708,00€1mL*10mM (DMSO)124,00€ONO-7300243
CAS:ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).Fórmula:C28H31NO5Pureza:99.66%Cor e Forma:SolidPeso molecular:461.55Ki16425
CAS:Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.Fórmula:C23H23ClN2O5SPureza:97.6% - 97.78%Cor e Forma:SolidPeso molecular:474.96Tetradecyl Phosphonate
CAS:Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。Fórmula:C14H31O3PPureza:99.95%Cor e Forma:White To Off-White PowderPeso molecular:278.37AM095
CAS:AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.Fórmula:C27H23N2NaO5Pureza:98.87%Cor e Forma:SolidPeso molecular:478.47Ref: TM-T2000
1mg34,00€2mg44,00€5mg63,00€10mg92,00€25mg170,00€50mg268,00€100mg416,00€1mL*10mM (DMSO)66,00€AM966
CAS:AM966, a excellent affinity, specific, oral LPA1(IC50=17 nM) antagonist, suppresses LPA-stimulated intracellular calcium release.Fórmula:C27H23ClN2O5Pureza:98.06% - 99.79%Cor e Forma:SolidPeso molecular:490.93BMS-986020
CAS:BMS-986020 (AM152) is a selective antagonist of LPA1.Fórmula:C29H26N2O5Pureza:98.82% - >99.99%Cor e Forma:SolidPeso molecular:482.531-Oleoyl lysophosphatidic acid sodium
CAS:1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2Fórmula:C21H40O7P·NaPureza:98.75% - 99.24%Cor e Forma:SolidPeso molecular:458.51BMS-986278
CAS:BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1,
Fórmula:C22H31N5O5Pureza:99.86%Cor e Forma:SolidPeso molecular:445.51Radioprotectin-1
CAS:Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.Fórmula:C23H19ClN2O6SPureza:98.63% - 99.27%Cor e Forma:SolidPeso molecular:486.92Ref: TM-T12684
1mg81,00€5mg170,00€10mg259,00€25mg425,00€50mg562,00€100mg775,00€1mL*10mM (DMSO)187,00€LPA2 antagonist 2
CAS:LPA2 antagonist 2 is an and LPA2 antagonist (IC50: 28.3 nM) with potential anticancer activity, inhibits LPA3, and can be used for cancer research.Fórmula:C20H16N2O6Pureza:96.13%Cor e Forma:SolidPeso molecular:380.35LPA2 antagonist 1
CAS:LPA2 antagonist 1 is a potent LPA2 antagonist.Fórmula:C20H23Cl2N5O2S2Pureza:99.85%Cor e Forma:SolidPeso molecular:500.47TC LPA5 4
CAS:TC LPA5 4 is a LPA5 receptor antagonist.Fórmula:C23H23ClN2O3Pureza:99.93%Cor e Forma:SolidPeso molecular:410.89Ref: TM-T23438
1mg49,00€5mg98,00€10mg157,00€25mg324,00€50mg485,00€100mg713,00€200mg982,00€1mL*10mM (DMSO)107,00€LPA1 receptor antagonist 1
CAS:LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a lysophosphatidic acid receptor antagonist for the study of idiopathic pulmonary fibrosis.Fórmula:C28H26N4O4Pureza:99.46% - 99.56%Cor e Forma:SolidPeso molecular:482.53
