Receptor de adenosina
Os receptores de adenosina são uma classe de GPCRs que respondem ao nucleosídeo endógeno adenosina. Esses receptores estão envolvidos na regulação de vários processos fisiológicos, incluindo função cardiovascular, ciclos de sono-vigília e respostas imunes. Moduladores de receptores de adenosina têm potencial terapêutico no tratamento de condições como arritmias cardíacas, inflamação e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de adenosina de alta qualidade para apoiar sua pesquisa em biologia cardiovascular, neurociência e imunologia.
Foram encontrados 249 produtos de "Receptor de adenosina"
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Theophylline-d6
CAS:Theophylline-d6, an internal standard for theophylline quantification in GC/LC-MS, relaxes bronchial muscles and treats asthma/COPD.Fórmula:C7H2D6N4O2Cor e Forma:SolidPeso molecular:186.2Norisoboldine
CAS:Norisoboldine, potential rheumatoid arthritis therapy, protects joints and modulates immunity by inhibiting MAPKs, not NF-κB.Fórmula:C18H19NO4Pureza:98.12% - 99.7%Cor e Forma:SolidPeso molecular:313.35SCH442416
CAS:SCH442416: selective A2A adenosine receptor antagonist; Ki: 0.048 nM (human), 0.5 nM (rat).Fórmula:C20H19N7O2Pureza:99.58%Cor e Forma:SolidPeso molecular:389.41Ref: TM-T23336
1mg46,00€5mg88,00€10mg132,00€25mg266,00€50mg409,00€100mg573,00€200mg807,00€1mL*10mM (DMSO)92,00€Derenofylline
CAS:Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM)Fórmula:C18H20N4OPureza:98.09%Cor e Forma:SolidPeso molecular:308.38ZM241385
CAS:ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor.
Fórmula:C16H15N7O2Pureza:97.02% - 99.69%Cor e Forma:SolidPeso molecular:337.34ABT-702 dihydrochloride
CAS:ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor.Fórmula:C22H21BrCl2N6OPureza:98.42% - 98.98%Cor e Forma:SolidPeso molecular:536.25Ref: TM-T4668
1mg58,00€2mg82,00€5mg113,00€10mg177,00€25mg333,00€50mg502,00€100mg710,00€500mg1.494,00€1mL*10mM (DMSO)133,00€Regadenoson hydrate
CAS:Regadenoson is an A2A adenosine receptor agonist, a coronary vasodilator commonly used in pharmacologic stress testing.Fórmula:C15H20N8O6Pureza:98%Cor e Forma:SolidPeso molecular:408.372-Chloroadenosine
CAS:2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectivelyFórmula:C10H12ClN5O4Pureza:99.23%Cor e Forma:White PowderPeso molecular:301.69Preladenant
CAS:Preladenant (SCH-420814) is an orally bioavailable antagonist of the adenosine A2A receptor (Ki: 1.1 nM) and has >1000-fold selectivity over all other adenosineFórmula:C25H29N9O3Pureza:98.02% - 99.68%Cor e Forma:SolidPeso molecular:503.56Xanthine amine congener hydrochloride
CAS:Xanthine amine congener (XAC) hydrochloride is a non-selective adenosine receptor antagonist that induces convulsions in mice.Fórmula:C21H29ClN6O4Cor e Forma:SolidPeso molecular:464.95Inosine
CAS:Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Low-Cost!Fórmula:C10H12N4O5Pureza:99.51% - 99.89%Cor e Forma:SolidPeso molecular:268.238-Cyclopentyl-1,3-dimethylxanthine
CAS:8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor.Fórmula:C12H16N4O2Pureza:98.58% - 99.9%Cor e Forma:SolidPeso molecular:248.28Nitrobenzylthioinosine
CAS:Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.
Fórmula:C17H17N5O6SPureza:99.69% - 99.74%Cor e Forma:Off-White SolidPeso molecular:419.41Tecadenoson
CAS:Tecadenoson (CVT-510) is a selective agonist of A1 adenosine receptor.
Fórmula:C14H19N5O5Pureza:98.83%Cor e Forma:SolidPeso molecular:337.33Binodenoson
CAS:Binodenoson (WRC 0470), a selective A2A adenosine receptor agonist, aids in coronary imaging.Fórmula:C17H25N7O4Pureza:99.74%Cor e Forma:SolidPeso molecular:391.42Ref: TM-T9516
1mg94,00€5mg222,00€10mg334,00€25mg557,00€50mg745,00€100mg1.044,00€1mL*10mM (DMSO)245,00€CHEMBL241987
CAS:CHEMBL241987 targets the Adenosine receptor A3 (human)Fórmula:C16H11N3OPureza:99.81%Cor e Forma:SolidPeso molecular:261.28CGS 21680 Hydrochloride
CAS:CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.Fórmula:C23H29N7O6·HClPureza:96.74% - 99.53%Cor e Forma:SolidPeso molecular:535.98Ref: TM-T6441
1mg38,00€2mg50,00€5mg81,00€10mg109,00€25mg215,00€50mg389,00€100mg575,00€1mL*10mM (DMSO)95,00€Enprofylline
CAS:Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.Fórmula:C8H10N4O2Pureza:98.37%Cor e Forma:SolidPeso molecular:194.19Ref: TM-T21389
2mg42,00€5mg62,00€10mg88,00€25mg141,00€50mg215,00€100mg318,00€200mg442,00€1mL*10mM (DMSO)59,00€Capadenoson
CAS:Capadenoson (BAY 68-4986) is a selective adenosine-A1 receptor agonist.Fórmula:C25H18ClN5O2S2Pureza:98.85% - 99.57%Cor e Forma:SolidPeso molecular:520.03SCH 58261
CAS:SCH 58261 is a potent and selective A2a adenosine receptor antagonist.The Ki =2.3 nM for rat A2a and 2 nM is for bovine A2a.Fórmula:C18H15N7OPureza:99.07% - 99.75%Cor e Forma:SolidPeso molecular:345.36Ref: TM-T6979
1mg40,00€2mg51,00€5mg85,00€10mg125,00€25mg225,00€50mg364,00€100mg582,00€1mL*10mM (DMSO)86,00€A2B receptor antagonist 2
CAS:A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).Fórmula:C12H15N5Pureza:100%Cor e Forma:SolidPeso molecular:229.28Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.
Fórmula:C23H26FN6O9PPureza:93.08% - 99.38%Cor e Forma:SolidPeso molecular:580.46Tozadenant
CAS:Tozadenant (SYN115) is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus,respectively)Fórmula:C19H26N4O4SPureza:98%Cor e Forma:SolidPeso molecular:406.5Alloxazine
CAS:Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.Fórmula:C10H6N4O2Pureza:99.75%Cor e Forma:SolidPeso molecular:214.18Taminadenant mesylate
CAS:Taminadenant (PBF-509/NIR-178) is an oral adenosine A2A receptor antagonist that activates T-cells to target tumor cells.Fórmula:C11H12BrN7O3SCor e Forma:SolidPeso molecular:402.227CPI-444
CAS:CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.Fórmula:C20H21N7O3Pureza:98.78%Cor e Forma:SolidPeso molecular:407.43Ref: TM-T7183
2mg34,00€5mg52,00€10mg73,00€25mg128,00€50mg197,00€100mg295,00€200mg442,00€1mL*10mM (DMSO)52,00€MIPS521
CAS:MIPS521 ({2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone) is a positive allosteric modulator of the A1R.Fórmula:C19H10ClF6NOSPureza:99.76%Cor e Forma:SolidPeso molecular:449.8Ref: TM-T9330
1mg35,00€2mg50,00€5mg74,00€10mg105,00€25mg178,00€50mg313,00€100mg485,00€1mL*10mM (DMSO)82,00€DPCPX
CAS:DPCPX (PD 116948) is an A1 adenosine receptor antagonistFórmula:C16H24N4O2Pureza:99.23% - 99.93%Cor e Forma:White SolidPeso molecular:304.39CCPA
CAS:CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptorFórmula:C15H20ClN5O4Pureza:99.1%Cor e Forma:Off-White To Light Yellow SolidPeso molecular:369.8Adenosine amine congener
CAS:Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.Fórmula:C28H32N8O6Pureza:97.86%Cor e Forma:SolidPeso molecular:576.6Vipadenant
CAS:Vipadenant (CEB-4520)(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69 nM).Fórmula:C16H15N7OPureza:97.25% - 97.36%Cor e Forma:SolidPeso molecular:321.34Ref: TM-T2373
2mg35,00€5mg51,00€10mg80,00€25mg131,00€50mg210,00€100mg313,00€200mg445,00€1mL*10mM (DMSO)215,00€PD 117519
CAS:PD 117519 (CI947) is an agonist of adenosine receptorFórmula:C19H21N5O4Pureza:99.98%Cor e Forma:SolidPeso molecular:383.4SDZ WAG 994
CAS:SDZ WAG 994 is an A1 adenosine receptor agonist.Fórmula:C17H25N5O4Pureza:99.82%Cor e Forma:SolidPeso molecular:363.41Ref: TM-T23347
1mg63,00€5mg114,00€10mg172,00€25mg299,00€50mg432,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)120,00€Namodenoson
CAS:Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.Fórmula:C18H18ClIN6O4Pureza:98.97%Cor e Forma:SolidPeso molecular:544.735-Iodotubercidin
CAS:5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM.
Fórmula:C11H13IN4O4Pureza:99.98%Cor e Forma:Tan SolidPeso molecular:392.15Taminadenant
CAS:Taminadenant is an adenosine receptor antagonist.Fórmula:C10H8BrN7Pureza:99.11%Cor e Forma:SolidPeso molecular:306.12Ref: TM-T16980
2mg34,00€5mg49,00€10mg84,00€25mg114,00€50mg166,00€100mg236,00€200mg353,00€1mL*10mM (DMSO)54,00€N6,N6-Dimethyladenosine
CAS:N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.
Fórmula:C12H17N5O4Pureza:98.79%Cor e Forma:White PowderPeso molecular:295.29AZD4635
CAS:AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).Fórmula:C15H11ClFN5Pureza:99.15% - 99.90%Cor e Forma:SolidPeso molecular:315.73Ref: TM-T4265
1mg37,00€2mg52,00€5mg79,00€10mg116,00€25mg188,00€50mg296,00€100mg457,00€500mg1.008,00€1mL*10mM (DMSO)87,00€1-Ethyl-6-aminouracil
CAS:1-Ethyl-6-aminouracil (6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE) is an intermediate in the synthesis of a series of new substituted Xanthines which have highFórmula:C6H9N3O2Pureza:99.29%Cor e Forma:SolidPeso molecular:155.15BAY-545
CAS:BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).Fórmula:C18H22F3N3O4SPureza:98.05%Cor e Forma:SolidPeso molecular:433.45Ref: TM-T8512
1mg84,00€5mg161,00€10mg235,00€25mg420,00€50mg605,00€100mg842,00€200mg1.134,00€1mL*10mM (DMSO)172,00€Regadenoson
CAS:Regadenoson (CVT-3146) is a selective A2A receptor agonist that increases coronary blood flow with a longer half-life than adenosine.Fórmula:C15H18N8O5Pureza:99.57% - 99.81%Cor e Forma:Off-White SolidPeso molecular:390.35Ref: TM-T2671
2mg47,00€5mg65,00€10mg92,00€25mg173,00€50mg273,00€100mg416,00€500mg935,00€1mL*10mM (DMSO)72,00€Reversine
CAS:Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).Fórmula:C21H27N7OPureza:98% - 99.45%Cor e Forma:SolidPeso molecular:393.49Ref: TM-T1825
1mg35,00€2mg50,00€5mg66,00€10mg84,00€25mg156,00€50mg212,00€100mg371,00€1mL*10mM (DMSO)66,00€Swertisin
CAS:Swertisin: an herbal molecule with antihyperglycemic, antidiabetic, anti-inflammatory, and antioxidant properties; blocks adenosine A1 receptor.Fórmula:C22H22O10Pureza:99.74% - 99.89%Cor e Forma:SolidPeso molecular:446.40Adenosine receptor antagonist 4
CAS:Adenosine receptor antagonist 4 is an adenosine receptor antagonist.Fórmula:C10H13N3Pureza:99.63% - 99.65%Cor e Forma:Off-White PowderPeso molecular:175.23Istradefylline
CAS:Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails.Fórmula:C20H24N4O4Pureza:98.18% - 99.95%Cor e Forma:SolidPeso molecular:384.43VPC171
CAS:VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).Fórmula:C18H12F3NOSPureza:99.78%Cor e Forma:SolidPeso molecular:347.35Ref: TM-T29112
1mg49,00€5mg96,00€10mg124,00€25mg222,00€50mg309,00€100mg439,00€200mg592,00€1mL*10mM (DMSO)88,00€Piclidenoson
CAS:Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.Fórmula:C18H19IN6O4Pureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:510.29Ref: TM-T7188
2mg42,00€5mg62,00€10mg89,00€25mg183,00€50mg298,00€100mg464,00€200mg663,00€1mL*10mM (DMSO)70,00€5'-N-Ethylcarboxamidoadenosine
CAS:NECA, an adenosine receptor agonist, boosts brain extravasation of fluorescein and dextran without affecting the blood-brain barrier.Fórmula:C12H16N6O4Pureza:98.95% - ≥95%Cor e Forma:PowderPeso molecular:308.29Proxyphylline
CAS:Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor.Fórmula:C10H14N4O3Pureza:99.48%Cor e Forma:SolidPeso molecular:238.24Rolofylline
CAS:Rolofylline (KW-3902) is an adenosine A1 receptor antagonist used to study acute congestive heart failure and renal dysfunction.Fórmula:C20H28N4O2Pureza:99.53%Cor e Forma:SolidPeso molecular:356.46
