Receptor de adenosina
Os receptores de adenosina são uma classe de GPCRs que respondem ao nucleosídeo endógeno adenosina. Esses receptores estão envolvidos na regulação de vários processos fisiológicos, incluindo função cardiovascular, ciclos de sono-vigília e respostas imunes. Moduladores de receptores de adenosina têm potencial terapêutico no tratamento de condições como arritmias cardíacas, inflamação e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de adenosina de alta qualidade para apoiar sua pesquisa em biologia cardiovascular, neurociência e imunologia.
Foram encontrados 242 produtos de "Receptor de adenosina"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Xanthine amine congener hydrochloride
CAS:<p>Xanthine amine congener (XAC) hydrochloride is a non-selective adenosine receptor antagonist that induces convulsions in mice.</p>Fórmula:C21H29ClN6O4Cor e Forma:SolidPeso molecular:464.95Norisoboldine
CAS:<p>Norisoboldine, potential rheumatoid arthritis therapy, protects joints and modulates immunity by inhibiting MAPKs, not NF-κB.</p>Fórmula:C18H19NO4Pureza:98.12% - 99.7%Cor e Forma:SolidPeso molecular:313.35SCH442416
CAS:<p>SCH442416: selective A2A adenosine receptor antagonist; Ki: 0.048 nM (human), 0.5 nM (rat).</p>Fórmula:C20H19N7O2Pureza:99.58%Cor e Forma:SolidPeso molecular:389.41Derenofylline
CAS:<p>Derenofylline is a selective and potent adenosine A(1) antagonist in vitro (Ki=1 nM)</p>Fórmula:C18H20N4OPureza:98.09%Cor e Forma:SolidPeso molecular:308.38CGS 21680 Hydrochloride
CAS:<p>CGS 21680 Hydrochloride (CGS 21680 HCl)(IC50=22 nM), an adenosine receptor agonist, exhibits 140-fold potency in A2 receptor over A1 receptor.</p>Fórmula:C23H29N7O6·HClPureza:96.74% - 99.53%Cor e Forma:SolidPeso molecular:535.98Regadenoson hydrate
CAS:<p>Regadenoson is an A2A adenosine receptor agonist, a coronary vasodilator commonly used in pharmacologic stress testing.</p>Fórmula:C15H20N8O6Pureza:98%Cor e Forma:SolidPeso molecular:408.37Preladenant
CAS:<p>Preladenant (SCH-420814) is an orally bioavailable antagonist of the adenosine A2A receptor (Ki: 1.1 nM) and has >1000-fold selectivity over all other adenosine</p>Fórmula:C25H29N9O3Pureza:98.02% - 99.68%Cor e Forma:SolidPeso molecular:503.56ZM241385
CAS:<p>ZM-241385 is a high-affinity antagonist ligand selective for the adenosine A2A receptor.</p>Fórmula:C16H15N7O2Pureza:97.02% - 99.69%Cor e Forma:SolidPeso molecular:337.348-Cyclopentyl-1,3-dimethylxanthine
CAS:<p>8-Cyclopentyl-1,3-dimethylxanthine (CPT) is a potent antagonist of adenosine A1 receptor.</p>Fórmula:C12H16N4O2Pureza:98.58% - >99.99%Cor e Forma:SolidPeso molecular:248.28CHEMBL241987
CAS:<p>CHEMBL241987 targets the Adenosine receptor A3 (human)</p>Fórmula:C16H11N3OPureza:99.81%Cor e Forma:SolidPeso molecular:261.28Inosine
CAS:<p>Inosine (NSC-20262), an endogenous purine nucleoside produced by the catabolism of adenosine, is an agonist of adenosine receptors A1R and A2AR. Low-Cost!</p>Fórmula:C10H12N4O5Pureza:99.51% - 99.89%Cor e Forma:SolidPeso molecular:268.23Tecadenoson
CAS:<p>Tecadenoson (CVT-510) is a selective agonist of A1 adenosine receptor.</p>Fórmula:C14H19N5O5Pureza:98.83%Cor e Forma:SolidPeso molecular:337.332-Chloroadenosine
CAS:<p>2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively</p>Fórmula:C10H12ClN5O4Pureza:99.23%Cor e Forma:White PowderPeso molecular:301.69ABT-702 dihydrochloride
CAS:<p>ABT-702 dihydrochloride is a potent adenosine kinase (AK) inhibitor.</p>Fórmula:C22H21BrCl2N6OPureza:98.42% - 98.98%Cor e Forma:SolidPeso molecular:536.25Tozadenant
CAS:<p>Tozadenant (SYN115) is an adenosine A2A receptor antagonist(Ki of 11.5 nM and 6 nM on human and rhesus,respectively)</p>Fórmula:C19H26N4O4SPureza:98%Cor e Forma:SolidPeso molecular:406.5SCH 58261
CAS:<p>SCH 58261 is a potent and selective A2a adenosine receptor antagonist.The Ki =2.3 nM for rat A2a and 2 nM is for bovine A2a.</p>Fórmula:C18H15N7OPureza:99.07% - 99.75%Cor e Forma:SolidPeso molecular:345.36Alloxazine
CAS:<p>Alloxazine (Isoalloxazine) is an A2 receptor antagonist, which is approximately 10-fold more selective for the A2B receptor than for the A2A receptor.</p>Fórmula:C10H6N4O2Pureza:99.75%Cor e Forma:SolidPeso molecular:214.18Reversine
CAS:<p>Reversine, a small synthetic purine analogue (2, 6-disubstituted purine), is a potent inhibitior of Aurora A/B/C(IC50s=150-500 nM).</p>Fórmula:C21H27N7OPureza:98% - 98.42%Cor e Forma:SolidPeso molecular:393.49Fostamatinib
CAS:<p>Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.</p>Fórmula:C23H26FN6O9PPureza:93.08% - 99.38%Cor e Forma:SolidPeso molecular:580.46Capadenoson
CAS:<p>Capadenoson (BAY 68-4986) is a selective adenosine-A1 receptor agonist.</p>Fórmula:C25H18ClN5O2S2Pureza:98.85% - 99.57%Cor e Forma:SolidPeso molecular:520.03Adenosine amine congener
CAS:<p>Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.</p>Fórmula:C28H32N8O6Pureza:97.86%Cor e Forma:SolidPeso molecular:576.6CPI-444
CAS:<p>CPI-444 (V81444) is an antagonist of the adenosine A2A receptor.It reduces tumor area in mouse model of murine Her2/neu-expressing breast cancer.</p>Fórmula:C20H21N7O3Pureza:98.78%Cor e Forma:SolidPeso molecular:407.43A2B receptor antagonist 2
CAS:<p>A2B receptor antagonist 2 is an antagonist of adenosine receptor A2B (Ki = 2.30 μM for rA1, 6.8 μM for rA2A, 3.44 μM for hA2B).</p>Fórmula:C12H15N5Pureza:100%Cor e Forma:SolidPeso molecular:229.28Proxyphylline
CAS:<p>Proxyphylline (7-(2-Hydroxypropyl)theophylline) is a dual of adenosine A1/A2a receptor inhibitor and phosphodiesterase (PDE) inhibitor.</p>Fórmula:C10H14N4O3Pureza:99.48%Cor e Forma:SolidPeso molecular:238.24CCPA
CAS:<p>CCPA (2-chloro-N(6)cyclopentyladenosine) is a potent and selective agonist of adenosine A1 receptor</p>Fórmula:C15H20ClN5O4Pureza:99.1%Cor e Forma:Off-White To Light Yellow SolidPeso molecular:369.8DPCPX
CAS:<p>DPCPX (PD 116948) is an A1 adenosine receptor antagonist</p>Fórmula:C16H24N4O2Pureza:99.23% - 99.93%Cor e Forma:White SolidPeso molecular:304.39Nitrobenzylthioinosine
CAS:<p>Nitrobenzylthioinosine (NBMPR) is an inhibitor of ENT1 transporter that binds to ENT1 transporter with high affinity.</p>Fórmula:C17H17N5O6SPureza:99.69% - 99.74%Cor e Forma:Off-White SolidPeso molecular:419.41Vipadenant
CAS:<p>Vipadenant (CEB-4520)(BIIB-014) is an adenosine A2a antagonist with Ki of 1.3 nM; less potent for A1(Ki=69 nM).</p>Fórmula:C16H15N7OPureza:97.25% - 97.36%Cor e Forma:SolidPeso molecular:321.34PD 117519
CAS:<p>PD 117519 (CI947) is an agonist of adenosine receptor</p>Fórmula:C19H21N5O4Pureza:99.98%Cor e Forma:SolidPeso molecular:383.4SDZ WAG 994
CAS:<p>SDZ WAG 994 is an A1 adenosine receptor agonist.</p>Fórmula:C17H25N5O4Pureza:99.82%Cor e Forma:SolidPeso molecular:363.41MIPS521
CAS:<p>MIPS521 ({2-Amino-4-[3,5-bis(trifluoromethyl)phenyl]thiophen-3-yl}(4-chlorophenyl)methanone) is a positive allosteric modulator of the A1R.</p>Fórmula:C19H10ClF6NOSPureza:99.76%Cor e Forma:SolidPeso molecular:449.8Namodenoson
CAS:<p>Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.</p>Fórmula:C18H18ClIN6O4Pureza:98.97%Cor e Forma:SolidPeso molecular:544.73Regadenoson
CAS:<p>Regadenoson (CVT-3146) is a selective A2A receptor agonist that increases coronary blood flow with a longer half-life than adenosine.</p>Fórmula:C15H18N8O5Pureza:99.57% - 99.81%Cor e Forma:Off-White SolidPeso molecular:390.355'-N-Ethylcarboxamidoadenosine
CAS:<p>NECA, an adenosine receptor agonist, boosts brain extravasation of fluorescein and dextran without affecting the blood-brain barrier.</p>Fórmula:C12H16N6O4Pureza:98.95% - ≥95%Cor e Forma:PowderPeso molecular:308.295-Iodotubercidin
CAS:<p>5-Iodotubercidin (NSC-113939) is a potent adenosine kinase inhibitor with IC50 of 26 nM.</p>Fórmula:C11H13IN4O4Pureza:99.98%Cor e Forma:Tan SolidPeso molecular:392.15Taminadenant
CAS:<p>Taminadenant is an adenosine receptor antagonist.</p>Fórmula:C10H8BrN7Pureza:99.11%Cor e Forma:SolidPeso molecular:306.12AZD4635
CAS:<p>AZD4635 (HTL1071) is a new-type adenosine 2A receptor (A2AR) inhibitor(Ki=1.7 nM).</p>Fórmula:C15H11ClFN5Pureza:99.15% - 99.90%Cor e Forma:SolidPeso molecular:315.73VPC171
CAS:<p>VPC171 is a novel adenosine A1 receptor positive allosteric modulator (PAM).</p>Fórmula:C18H12F3NOSPureza:99.78%Cor e Forma:SolidPeso molecular:347.35BAY-545
CAS:<p>BAY-545 is an antagonist of A2B adenosine receptor(IC50 : 59 nM).</p>Fórmula:C18H22F3N3O4SPureza:98.05%Cor e Forma:SolidPeso molecular:433.45Piclidenoson
CAS:<p>Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.</p>Fórmula:C18H19IN6O4Pureza:99.83% - ≥95%Cor e Forma:SolidPeso molecular:510.29Istradefylline
CAS:<p>Istradefylline (KW-6002)(Ki of 2.2 nM) is a selective adenosine A2A receptor (A2AR) antagonist, which is under development in Phase 3 trails.</p>Fórmula:C20H24N4O4Pureza:98.18% - 99.95%Cor e Forma:SolidPeso molecular:384.43Enprofylline
CAS:<p>Enprofylline (Enprofilina), a bronchodilator, acts primarily as a competitive nonselective phosphodiesterase inhibitor.</p>Fórmula:C8H10N4O2Pureza:98.37%Cor e Forma:SolidPeso molecular:194.19Swertisin
CAS:<p>Swertisin: an herbal molecule with antihyperglycemic, antidiabetic, anti-inflammatory, and antioxidant properties; blocks adenosine A1 receptor.</p>Fórmula:C22H22O10Pureza:99.74% - 99.89%Cor e Forma:SolidPeso molecular:446.4Adenosine receptor antagonist 4
CAS:<p>Adenosine receptor antagonist 4 is an adenosine receptor antagonist.</p>Fórmula:C10H13N3Pureza:99.63% - 99.65%Cor e Forma:Off-White PowderPeso molecular:175.231-Ethyl-6-aminouracil
CAS:<p>1-Ethyl-6-aminouracil (6-AMINO-1-ETHYL-1H-PYRIMIDINE-2,4-DIONE) is an intermediate in the synthesis of a series of new substituted Xanthines which have high</p>Fórmula:C6H9N3O2Pureza:99.29%Cor e Forma:SolidPeso molecular:155.15N6,N6-Dimethyladenosine
CAS:<p>N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.</p>Fórmula:C12H17N5O4Pureza:98.79%Cor e Forma:White PowderPeso molecular:295.29Binodenoson
CAS:<p>Binodenoson (WRC 0470), a selective A2A adenosine receptor agonist, aids in coronary imaging.</p>Fórmula:C17H25N7O4Pureza:99.74%Cor e Forma:SolidPeso molecular:391.42Rolofylline
CAS:<p>Rolofylline (KW-3902) is an adenosine A1 receptor antagonist used to study acute congestive heart failure and renal dysfunction.</p>Fórmula:C20H28N4O2Pureza:99.53%Cor e Forma:SolidPeso molecular:356.46Trabodenoson
CAS:<p>Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma.</p>Fórmula:C15H20N6O6Pureza:99.94%Cor e Forma:SolidPeso molecular:380.365'-Amino-5'-deoxyadenosine
CAS:<p>5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer</p>Fórmula:C10H14N6O3Pureza:95.55%Cor e Forma:SolidPeso molecular:266.26
