Receptor de adenosina
Os receptores de adenosina são uma classe de GPCRs que respondem ao nucleosídeo endógeno adenosina. Esses receptores estão envolvidos na regulação de vários processos fisiológicos, incluindo função cardiovascular, ciclos de sono-vigília e respostas imunes. Moduladores de receptores de adenosina têm potencial terapêutico no tratamento de condições como arritmias cardíacas, inflamação e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de adenosina de alta qualidade para apoiar sua pesquisa em biologia cardiovascular, neurociência e imunologia.
Foram encontrados 249 produtos de "Receptor de adenosina"
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Inupadenant
CAS:Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity[1].Fórmula:C25H26F2N8O4S2Cor e Forma:SolidPeso molecular:604.65CAY10680
CAS:CAY10680 inhibits MAO-B (IC50=34.9 nM) & A2A receptors (Ki=39.5 nM), sparing other adenosine types & MAO-A, may treat Parkinson's.Fórmula:C18H16N2O2SCor e Forma:SolidPeso molecular:324.4FR-194921
CAS:FR-194921: potent oral adenosine A1 antagonist, improves cognition, reduces anxiety, similar efficacy in humans, rats, mice.Fórmula:C23H23N5OCor e Forma:SolidPeso molecular:385.46CVT-2759
CAS:CVT-2759, potential A(1)-ADOR partial agonist, could slow ventricular rate without severe cardiac side effects.Fórmula:C17H24N6O6Cor e Forma:SolidPeso molecular:408.41Adenosine receptor inhibitor 2
CAS:Compound 14b is a potent AR inhibitor with dual affinity, stronger for A1 (Ki = 52.2 nM) than A2A (Ki = 167 nM) ARs.Fórmula:C17H20BrN5O2Cor e Forma:SolidPeso molecular:406.28Acefylline piperazine
CAS:Acefylline piperazine, a less toxic theophylline derivative, treats asthma and bronchitis by bronchodilation, stimulating respiration and CNS.Fórmula:C9H10N4O4·xC4H10N2Cor e Forma:SolidPeso molecular:562.54JNJ-40255293
CAS:JNJ-40255293 is an antagonist of adenosine A2A/A1.Fórmula:C23H22N4O3Pureza:98%Cor e Forma:SolidPeso molecular:402.45AK-IN-1
CAS:AK-IN-1: competitive adenosine inhibitor, not ATP; inhibits AK 86-89% at 2-10 µM; promising for ischaemia, inflammation, seizure research.Fórmula:C22H21N3O4Cor e Forma:SolidPeso molecular:391.42ATL-801
CAS:ATL-801 is anselective antagonist of A2B receptor with herapeutic activity for colitis.Fórmula:C24H25N7O3Cor e Forma:SolidPeso molecular:459.5Kira8 Hydrochloride
CAS:Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.Fórmula:C31H30Cl2N6O3SPureza:98%Cor e Forma:SolidPeso molecular:637.58A2AAR/HDAC-IN-2
CAS:A2AAR/HDAC-IN-2: potent dual A2AAR/HDAC inhib., Ki 10.3 nM, IC50 18.5 nM, anti-tumor potential.Fórmula:C23H26N6O4Cor e Forma:SolidPeso molecular:450.49Theophylline sodium glycinate
CAS:Theophylline sodium glycinate inhibits PDE3, treats asthma/COPD, blocks adenosine receptors, activates HDAC, reduces inflammation and induces apoptosis.Fórmula:C9H12N5NaO4Cor e Forma:SolidPeso molecular:277.216hA2AAR antagonist 1
CAS:Compound 4a, also known as hA2AAR antagonist 1, is a highly selective hA2AAR antagonist with a Ki value of 5 nM. It is useful in the field of immuno-oncology research.Fórmula:C15H15N5OCor e Forma:SolidPeso molecular:281.31LUF5831
CAS:LUF5831 is an agonist of adenosine A1 receptor.Fórmula:C15H12N4O2SCor e Forma:SolidPeso molecular:312.35Draflazine
CAS:Draflazine: ENT1 inhibitor, reverses hypersensitivity in CFA and carrageenan-induced hyperalgesia.Fórmula:C30H33Cl2F2N5O2Pureza:98%Cor e Forma:SolidPeso molecular:604.52LUF5981
CAS:LUF5981 is a selective agonist of human adenosine A1 receptor.Fórmula:C24H23N3Cor e Forma:SolidPeso molecular:353.46Cirazoline hydrochloride
CAS:Cirazoline hydrochloride is a synthetic competitive full agonist of α1A-AR (Ki 120 nM) and partial agonist at α1B-AR and α1D-AR.Fórmula:C13H17ClN2OPureza:99.863%Cor e Forma:SolidPeso molecular:252.74Bamifylline Hydrochloride
CAS:Bamifylline Hydrochloride, an adenosine A1 receptor antagonist, is uesd to treat bronchiectasis and chronic obstructive pulmonary disease.Fórmula:C20H28ClN5O3Cor e Forma:SolidPeso molecular:421.92MRS1067
CAS:MRS1067 is an antagonist of A3 adenosine receptor.Fórmula:C19H16Cl2O3Cor e Forma:SolidPeso molecular:363.23VUF8504
CAS:VUF8504 is a novel ligand of adenosine A3 receptor.Fórmula:C22H17N3O2Cor e Forma:SolidPeso molecular:355.39WRC-0571
CAS:WRC-0571 is a highly potent, selective antagonist of A1 adenosine receptors.Fórmula:C17H26N6OPureza:98%Cor e Forma:SolidPeso molecular:330.43Naxifylline
CAS:Naxifylline is an A1 adenosine receptor blocker that increases urine and protects kidneys during edema treatment in heart failure.Fórmula:C18H24N4O3Cor e Forma:SolidPeso molecular:344.41CP 66713
CAS:CP-66713 is an adenosine A2 receptor antagonist.Fórmula:C15H10ClN5Cor e Forma:SolidPeso molecular:295.73A2AAR antagonist 1
CAS:Compound 21a, A2AAR antagonist with 20 nM Ki, useful in neurodegenerative disease study.Fórmula:C12H8BrN3OCor e Forma:SolidPeso molecular:290.12MRE3008F20
CAS:MRE3008F20 is an AA3R antagonist that inhibits Cl-IB-MECA-induced cAMP production and can be used to study glaucoma and asthma.Fórmula:C21H20N8O3Pureza:97.29%Cor e Forma:SolidPeso molecular:432.44A2AR-antagonist-1
CAS:Oral A2AR-antagonist-1, IC50 29 nM; anti-tumor, stable in mice (t1/2 86.1 min), boosts T cells, impedes LAG-3/TIM-3.Fórmula:C27H25N5O2Pureza:98%Cor e Forma:SolidPeso molecular:451.52VUF 5574
CAS:VUF 5574 is a selective antagonist of adenosine A3 receptor with a Ki of 4.03 nM for the recombinant human receptor.Fórmula:C21H17N5O2Pureza:99.53%Cor e Forma:SolidPeso molecular:371.39ST3932
CAS:ST3932 is a ST1535 metabolite, is a adenosine A2A receptor antagonist(Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively).Fórmula:C12H16N8OPureza:98%Cor e Forma:SolidPeso molecular:288.31N6-Cyclopentyladenosine
CAS:N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's ofFórmula:C15H21N5O4Pureza:99.95%Cor e Forma:SolidPeso molecular:335.36N-[(4-Aminophenyl)methyl]adenosine
CAS:N-[(4-Aminophenyl)methyl]adenosine is an adenosine receptor inhibitor (Ki: 29 nM for Rat ecto-5′-Nucleotidase).Fórmula:C17H20N6O4Pureza:98.75%Cor e Forma:SolidPeso molecular:372.38Ref: TM-T16166
1mg52,00€5mg111,00€10mg166,00€25mg318,00€50mg504,00€100mg803,00€1mL*10mM (DMSO)141,00€Sonedenoson
CAS:Sonedenoson (MRE0094) is an adenosine A(2A) receptor agonist and potential inhibitor potentially targeting SARS-CoV-2 coronavirus 2;-O-ribose methyltransferase.Fórmula:C18H20ClN5O5Pureza:99.79%Cor e Forma:SolidPeso molecular:421.84KI-7
CAS:KI-7 is an adenosine A2B receptor positive allosteric modulator.Fórmula:C23H18N2O2Pureza:98.33%Cor e Forma:SolidPeso molecular:354.4Ref: TM-T9238
2mg35,00€5mg55,00€10mg95,00€25mg172,00€50mg264,00€100mg399,00€200mg560,00€1mL*10mM (DMSO)62,00€Adenosine antagonist-1
CAS:Adenosine antagonist-1 acts as an adenosine A3 receptor (AA3R) antagonist.
Fórmula:C18H13N7SPureza:99.28% - 99.95%Cor e Forma:SolidPeso molecular:359.41BAY 60-6583
CAS:BAY 60-6583 is a potent, high-affinity adenosine A2B receptor agonist (EC50 = 3 nM) with affinity for A2B receptors that exceeds that for A1, A2A, and A3Fórmula:C19H17N5O2SPureza:98.46% - 99.8%Cor e Forma:SolidPeso molecular:379.44Ref: TM-T14506
1mg39,00€2mg50,00€5mg84,00€10mg116,00€25mg233,00€50mg376,00€100mg567,00€200mg797,00€1mL*10mM (DMSO)101,00€GW-493838
CAS:GW-493838 is a potent adenosine A1A receptor agonist for the treatment of dyslipidemia and neuropathic pain, with analgesic effects on post-herpetic neuralgiaFórmula:C21H21ClFN7O4Pureza:99.11% - 99.58%Cor e Forma:SolidPeso molecular:489.89Ref: TM-T27509
1mg143,00€5mg346,00€10mg492,00€25mg740,00€50mg999,00€100mg1.350,00€500mg2.647,00€1mL*10mM (DMSO)399,00€ST-1535
CAS:ST 1535: potent, oral A2A adenosine receptor antagonist with antiparkinsonian and antitremor effects, promising for Parkinson's research.Fórmula:C12H16N8Pureza:99.64% - 99.69%Cor e Forma:SolidPeso molecular:272.31N6-(2-Phenylethyl)adenosine
CAS:N6-(2-Phenylethyl)adenosine (N6-Phenethyladenosine) is an adenosine derivative and an agonist of adenosine receptors with Ki values of 11.8 nM and 30.1 nM forFórmula:C18H21N5O4Pureza:99.83%Cor e Forma:SolidPeso molecular:371.39A2A receptor antagonist 1
CAS:A2A receptor antagonist 1 (CPI-444 analog) is an antagonist of both adenosine A2A receptor and A1 receptor with Kis of 4 and 264 nM, respectively.Fórmula:C16H12FN5OPureza:99.52% - 99.93%Cor e Forma:SolidPeso molecular:309.3Ref: TM-T37792
2mgA consultar5mg62,00€10mg87,00€25mg183,00€50mg280,00€100mg416,00€200mgA consultar1mL*10mM (DMSO)47,00€N 0861
CAS:N 0861 is a selective adenosine A1 receptor antagonist that attenuates renal insufficiency during adenosine-controlled hypotension in rats.Fórmula:C13H17N5Pureza:98.78%Cor e Forma:SolidPeso molecular:243.31Ref: TM-T70722
1mg164,00€2mg234,00€5mg389,00€10mg532,00€25mg820,00€50mg1.063,00€100mg1.423,00€200mg1.945,00€ANR 94
CAS:ANR94 is a potent hAA2AR antagonist (Ki 46 nM) with potential for Parkinson's research.Fórmula:C9H13N5OPureza:98.9%Cor e Forma:SolidPeso molecular:207.23Ref: TM-T22031
5mg46,00€10mg71,00€25mg130,00€50mg219,00€100mg309,00€200mg434,00€1mL*10mM (DMSO)46,00€ISAM-140
CAS:ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.Fórmula:C19H19N3O3Pureza:99.51%Cor e Forma:SolidPeso molecular:337.37GS-9667
CAS:GS-9667, a selective and partial agonist of the A(1) adenosine receptor (AR), represents an effective therapy for Type 2 diabetes (T2DM) and dyslipidemia viaFórmula:C21H24FN5O4SPureza:99.77% - 99.96%Cor e Forma:SolidPeso molecular:461.51APNEA
CAS:APNEA ((2R,3R,4S,5R)-2-[6-[2-(4-aminophenyl)ethylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol) is a non-selective agonist of adenosine A3 receptor.Fórmula:C18H22N6O4Pureza:99.88%Cor e Forma:SolidPeso molecular:386.41LAS38096
CAS:LAS38096 is an A2B adenosine receptor antagonist (Ki : 17 nM) that is potent, selective and efficient .Fórmula:C17H12N6OPureza:99.18% - 99.95%Cor e Forma:SolidPeso molecular:316.32Evodenoson
CAS:Evodenoson (ATL313), a potent A2aR agonist, treats eye diseases, tumors, and immune disorders; potential for glaucoma and blood cancer studies.Fórmula:C23H29N7O6Pureza:99.75% - 99.83%Cor e Forma:SolidPeso molecular:499.52MRS1220
CAS:MRS1220, a selective and potent antagonist for the human A3 adenosine receptor (hA3AR) with a dissociation constant (Ki) of 0.59 nM, exhibits therapeuticFórmula:C21H14ClN5O2Pureza:98.43%Cor e Forma:SolidPeso molecular:403.822'-MeCCPA
CAS:2'-MeCCPA is an A1AR agonist that inhibits trichothecene-stimulated adenylate cyclase activity and has analgesic activity for the study of HCV.Fórmula:C16H22ClN5O4Pureza:99.93%Cor e Forma:SolidPeso molecular:383.83FK-453
CAS:FK-453 is a potent antagonist of non-xanthine adenosine A1 receptor with diuretic and renal vasodilatory activity.Fórmula:C23H25N3O2Pureza:99.44%Cor e Forma:SolidPeso molecular:375.46Selodenoson
CAS:Selodenoson (RG-14202) is a selective adenosine A1 receptor agonist used to slow the heart rate in patients with atrial fibrillation and to treat arrhythmias.Fórmula:C17H24N6O4Pureza:99.39%Cor e Forma:SolidPeso molecular:376.41Neladenoson dalanate
CAS:Neladenoson dalanate (BAY-1067197), an oral Adenosine A1 receptor partial agonist, is safe with good pharmacokinetics for chronic heart disease.Fórmula:C35H34ClN7O4S2Cor e Forma:SolidPeso molecular:716.27
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