Receptor de adenosina
Os receptores de adenosina são uma classe de GPCRs que respondem ao nucleosídeo endógeno adenosina. Esses receptores estão envolvidos na regulação de vários processos fisiológicos, incluindo função cardiovascular, ciclos de sono-vigília e respostas imunes. Moduladores de receptores de adenosina têm potencial terapêutico no tratamento de condições como arritmias cardíacas, inflamação e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de adenosina de alta qualidade para apoiar sua pesquisa em biologia cardiovascular, neurociência e imunologia.
Foram encontrados 249 produtos de "Receptor de adenosina"
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MRS 1754
CAS:MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor. It has a very low affinity for A1 and A3 receptors of both humans and rats.
Fórmula:C26H26N6O4Pureza:97.57% - 99.3%Cor e Forma:SolidPeso molecular:486.52ABT-702 hydrochloride
CAS:ABT-702 hydrochloride effectively inhibits adenosine kinase, exhibiting an IC50 value of 1.7 nM [1] [2].Fórmula:C22H20BrClN6OCor e Forma:SolidPeso molecular:499.79PSB-1115 potassium salt
CAS:PSB-1115 potassium salt, a selective A2B Adenosine Receptor antagonist, inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) [1].Fórmula:C14H13KN4O5SCor e Forma:SolidPeso molecular:388.44A2B receptor antagonist 1
CAS:A2B receptor antagonist 1 (EXAMPLE 9B) is a potent A2B adenosine receptor antagonist.Fórmula:C21H24N6O2Pureza:99.53%Cor e Forma:SolidPeso molecular:392.45Ref: TM-T10058
1mg349,00€5mg697,00€10mg888,00€25mg1.395,00€50mg1.783,00€100mg2.530,00€1mL*10mM (DMSO)800,00€PSB-603
CAS:PSB-603 is a selective antagonist of Adenosine A2B receptor(Ki = 0.553 nM) with anti-inflammatory effects.
Fórmula:C24H25ClN6O4SPureza:97.13%Cor e Forma:SolidPeso molecular:529.01PSB 1115
CAS:PSB 1115 is an A2B receptor antagonist and can counteract the inhibitory effect of NECA.Fórmula:C14H14N4O5SPureza:98.69% - >99.99%Cor e Forma:SolidPeso molecular:350.35LJ-4517
LJ-4517 is an effective A2AAR antagonist (Ki=18.3 nM). LJ-4517 can effectively replace the binding of [3H] ZM241385 at WT A2AAR.Fórmula:C19H21N5O3SCor e Forma:SolidPeso molecular:399.47Zaladenant
CAS:Zaladenant is an adenosine receptor antagonist with antitumor properties.Fórmula:C19H15F3N6OCor e Forma:SolidPeso molecular:400.357M1069
M1069 is an oral A2A/A2B receptor antagonist, 100x more selective over A1/A3, with antitumor properties by blocking adenosine's immunosuppressive effects.Fórmula:C25H30N4O8SCor e Forma:SolidPeso molecular:546.59CVT-5440
CAS:CVT-5440 is a selective, high-affinity (2B) adenosine receptor antagonist with good selectivity.Fórmula:C27H28N6O5Cor e Forma:SolidPeso molecular:516.55A1AR antagonist 1
Compound 18g, a potent A1AR blocker with Ki: 2.08 nM (hA1), 6.91 nM (hA2A), 31.2 nM (hA2B).Fórmula:C18H14N4OCor e Forma:SolidPeso molecular:302.33DMPX
CAS:DMPX (3,7-Dimethyl-1-propargylxanthine) is a caffeine-like compound capable of crossing the blood-brain barrier. It serves as an A2-selective adenosine receptor (AR) antagonist, effectively and selectively blocking the hypothermia and behavioral inhibition induced by A2 adenosine receptor agonists, such as NECA. DMPX is utilized in research on diseases like Parkinson's disease.Fórmula:C10H10N4O2Cor e Forma:SolidPeso molecular:218.212A3AR antagonist 5
CAS:A3AR antagonist 5 (Compound 16) acts as a selective antagonist for the human adenosine A3 receptor (human adenosine A3 receptor), with an affinity expressed as a pC value of 4.542 μM.Fórmula:C18H16N2O2SCor e Forma:SolidPeso molecular:324.40ADORA2A/PDE4D-IN-1
CAS:ADORA2A/PDE4D-IN-1 (Compound 9) is a dual inhibitor of the adenosine A2a receptor (ADORA2A) and phosphodiesterase 4D (PDE4D). This compound is applicable for research in bronchial asthma.Fórmula:C14H11N5Cor e Forma:SolidPeso molecular:249.271UK-432097
CAS:UK 432097 is an adenosine A2A agonist.Fórmula:C40H47N11O6Cor e Forma:SolidPeso molecular:777.87MSX-3
CAS:MSX-3 is an antagonist of the A2A adenosine receptor and a prodrug of MSX-2.Fórmula:C21H23N4Na2O7PPureza:98%Cor e Forma:SolidPeso molecular:520.389YGZ-331
CAS:YGZ-331, a sedative hypnotic, acts by elevating GABA levels as a derivative of the adenosine nucleoside NGBA. It functions through activating A1R and A2aR, and inhibiting the phosphorylation of CaMKII (pCaMKII), thereby exerting its calming effects. Additionally, YGZ-331 reduces spontaneous motor activity in mice.Fórmula:C19H23N5O4Cor e Forma:SolidPeso molecular:385.42CP-608039
CAS:CP-608039 is a selective adenosine A3 receptor agonist for both human A3 and human A1 receptors.Fórmula:C23H25ClN8O5Cor e Forma:SolidPeso molecular:528.95Tonapofylline
CAS:Tonapofylline, orally active, selectively blocks A1 adenosine receptor (Ki: 7.4 nM), used in heart failure research.Fórmula:C22H32N4O4Pureza:98.57%Cor e Forma:SolidPeso molecular:416.51MRS7799
CAS:MRS7799 is a selective A3 Adenosine Receptor antagonist with Kd values of 0.55 nM for humans, 3.74 nM for mice, and 2.80 nM for rats. MRS7799 can be utilized in research related to neurodegenerative diseases, cancer, cardiac and cerebral ischemia, and autoimmune inflammatory diseases.Fórmula:C22H18N4OSCor e Forma:SolidPeso molecular:386.47
